In an effort to develop a novel electronic paper image display technology based on the electrowetting principle, a 3-D electrowetting cell is designed and fabricated, which consists of two 3-D bent electrodes, each having a horizontal surface made of gold and a vertical surface made of indium tin oxide (ITO) glass as a color display window, a layer of dielectric material on the 3-D electrodes, and a highly fluorinated hydrophobic layer on the surface of the dielectric layer. Results of this work show that an electrowetting-induced motion of an aqueous droplet in immiscible oils can be achieved reversibly across the boundary of the horizontal and vertical surfaces of the 3-D electrode surface. It is also shown that the droplet can maintain its wetting state on a vertical sidewall electrode free of a power supplier when the voltage is removed. This phenomenon may form the basis for color contrast modulation applications, where a power-free image display is required, such as electronic paper display technology in the future.
This paper presents the design and experimental evaluation of a miniaturized fluorescence imaging instrument for genetic diagnostics on a biochip. It further demonstrates the capability of the instrument to perform multiple quantitative PCR in microscale.
In this paper, we present an integrated and automated prototype system which has been developed for real-time polymerase chain reaction (PCR) analysis based on microfluidic PCR array chips. The system integrates the PCR thermal cycling and optical detection capabilities to enable real-time fluorescence imaging and image processing for data analysis. The main advantage of the system is that it provides a solution that can rapidly perform and evaluate PCR experiment simultaneously on microfluidic PCR array chips. The system has demonstrated fast and efficient on-chip real-time PCR analysis using human genomic DNA samples. The implementation of the system integration is a multi-thread Windows software with component structure which is written in Visual C++.
A methodology for the simulation of a reciprocating displacement micro-pump is presented. First a check valve model was analyzed using coupled FEM to obtain the characteristics relationship between flow rate and the pressure as well as the minimum valve opening pressure. Then a model for the micro-pump actuator driven by PZT disks is proposed and simulated. The pump model takes into account the effects of chamber pressure and geometrical parameters. The maximum downward deflection of the actuating membrane is taken as the target parameter to analyze. It was found that the maximum membrane deflection could reach over 10micrometers microns, much larger than the radial displacement. This 'displacement amplification' is the underlying working principle of this kind of micro-pump. Quantitative analyses of the effects of various factors on the deflection are conducted. It is found that the thickness of the membrane has the biggest influence on the deflection. For each membrane thickness, there exists an op[t9kum PZT disk thickness that gives the maximum deflection at a particular electric field. Other factors with less influence on the deflection are also investigated. An optimum set of design parameters for the micro-pump is obtained form the analyses.
A novel micro-machined valveless diffuser-nozzle micropump is presented in the present paper. The micropump is designed by thermally bubble driven actuation method. This pumping mechanism requires no mechanical moving parts for actuation and control of inlet and outlet. As a result, it requires substantially simplified fabrication process in two wafers, which is compatible with IC fabrication processes. The proposed micropump will provide high actuation stroke than existing micropumps.
A novel micro-machined valve-less micro-injector has been demonstrated in the present paper. The micro-injector is designed by thermally bubble driven actuation method that requires no mechanical moving parts for actuation and control of droplets. The use of thermal bubble for actuation provides virtual chamber neck and virtual valves as well. Furthermore it offers simplified fabrication in a single wafer that is compatible with IC fabrication processes.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.