Conformal radiotherapy is a cancer treatment technique, that targets high-energy X-rays to tumors with minimal
exposure to surrounding healthy tissues. Irradiation ballistics is calculated based on an initial 3D Computerized
Tomography (CT) scan. At every treatment session, the random positioning of the patient, compared
to the reference position defined by the initial 3D CT scan, can generate treatment inaccuracies. Positioning
errors potentially predispose to dangerous exposure to healthy tissues as well as insufficient irradiation to the
tumor. A proposed solution would be the use of portal images generated by Electronic Portal Imaging Devices
(EPID). Portal images (PI) allow a comparison with reference images retained by physicians, namely Digitally
Reconstructed Radiographs (DRRs). At present, physicians must estimate patient positional errors by visual
inspection. However, this may be inaccurate and consumes time. The automation of this task has been the
subject of many researches. Unfortunately, the intensive use of DRRs and the high computing time required
have prevented real time implementation. We are currently investigating a new method for DRR generation that
calculates intermediate DRRs by 2D deformation of previously computed DRRs. We approach this investigation
with the use of a morphing-based technique named mesh warping.
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