Although diffuse reflectance measurement has convenience in obtaining spectra from skin, it has extremely low light efficiency compared with other configurations as the skin has forward scattering characteristics. To increase the amount of photon illumination and enhance SNR, we suggest a honeycombed optical skin interface with multi-fibers based probe for the diffuse reflectance measurement of skin. Experimental results with human and swine skin measurements show the spectral noise of the skin spectra in the range of 13~16 µAU and the effective water path length in the range of 1.8~2.2 mm. With this honeycombed skin interface, 5~6 times enhanced spectral SNR can be obtained.
A novel miniaturized near-infrared spectrometer readily mountable to wearable devices for continuous monitoring of individual’s key bio-markers was proposed. Spectrum is measured by sequential illuminations with LED’s, having independent spectrum profiles and a continuous detection of light radiations from the skin tissue with a single cell PD. Based on Tikhonov regularization with singular value decomposition, a spectrum resolution less than 10nm was reconstructed based on experimentally measured LED profiles. A prototype covering first overtone band (1500-1800nm) where bio-markers have pronounced absorption peaks was fabricated and verified of its performance. Reconstructed spectrum shows that the novel concept of miniaturized spectrometer is valid.
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