Dr. Igor R. Efimov Profile

Dr. Igor R. Efimov

The Lucy and Stanley Lopata Distinguished Prof at George Washington Univ

SPIE Involvement:

Author

Publications (8)

Proceedings Article | 14 March 2018 Presentation

Volumetric imaging of whole isolated beating heart with four-dimensional optoacoustic tomography (Conference Presentation)

Hasiao-Chun Amy Lin, Xosé Luís Deán-Ben, Igor Efimov, Daniel Razansky

Proceedings Volume 10471, 104710J (2018) https://doi.org/10.1117/12.2290820

KEYWORDS: Image resolution, Imaging systems, Luminescence, In vitro testing, Heart, Tomography, 3D image processing, Optical imaging, Tissue optics, Tissues

Read Abstract +

SPIE Journal Paper | 18 May 2012 Open Access

Quantification of fiber orientation in the canine atrial pacemaker complex using optical coherence tomography

Christina Ambrosi, Vadim Fedorov, Igor Efimov, Richard Schuessler, Andrew Rollins

JBO, Vol. 17, Issue 7, 071309, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.071309

KEYWORDS: Optical coherence tomography, Tissues, Heart, Tissue optics, Natural surfaces, Visualization, Computed tomography, Structured optical fibers, Imaging systems, Spatial resolution

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 September 2009 Open Access

Virtual histology of the human heart using optical coherence tomography

Christina Ambrosi, Nader Moazami, Andrew Rollins, Igor Efimov

JBO, Vol. 14, Issue 05, 054002, (September 2009) https://doi.org/10.1117/12.10.1117/1.3213604

KEYWORDS: Optical coherence tomography, Tissues, Heart, Natural surfaces, Optical fibers, Visualization, Imaging systems, Spatial resolution, Arteries, Computed tomography

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 September 2008 Open Access

Bimodal biophotonic imaging of the structure-function relationship in cardiac tissue

William Hucker, Crystal Ripplinger, Christine Fleming, Vadim Fedorov, Andrew Rollins, Igor Efimov

JBO, Vol. 13, Issue 05, 054012, (September 2008) https://doi.org/10.1117/12.10.1117/1.2975826

KEYWORDS: Optical coherence tomography, Tissue optics, Tissues, Natural surfaces, Biomedical optics, Associative arrays, Heart, 3D image processing, Photodiodes, Biomedical engineering

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 May 2008 Open Access

Quantification of cardiac fiber orientation using optical coherence tomography

Christine Fleming, Crystal Ripplinger, Bryan Webb, Igor Efimov, Andrew Rollins

JBO, Vol. 13, Issue 03, 030505, (May 2008) https://doi.org/10.1117/12.10.1117/1.2937470

KEYWORDS: Optical coherence tomography, 3D image processing, Heart, Algorithm development, Structured optical fibers, Image filtering, Tissues, Image processing, Solids, Image analysis

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 July 2007 Open Access

Three-dimensional panoramic imaging of cardiac arrhythmias in rabbit heart

Fujian Qu, Crystal Ripplinger, Vladimir Nikolski, Cindy Grimm, Igor Efimov

JBO, Vol. 12, Issue 04, 044019, (July 2007) https://doi.org/10.1117/12.10.1117/1.2753748

KEYWORDS: Heart, Personal digital assistants, Signal to noise ratio, Panoramic photography, Imaging systems, Action potentials, CCD cameras, Luminescence, 3D image processing, Light emitting diodes

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 13 April 2005 Paper

4D optical coherence tomography of the embryonic heart using gated imaging

Michael Jenkins, Florence Rothenberg, Debashish Roy, Vladimir Nikolski, David Wilson, Igor Efimov, Andrew Rollins

Proceedings Volume 5690, (2005) https://doi.org/10.1117/12.592385

KEYWORDS: Heart, Optical coherence tomography, 3D image processing, Gated imaging, 3D acquisition, 3D image reconstruction, Visualization, 3D metrology, Computed tomography, Ultrasonography

Read Abstract +

Computed tomography (CT), ultrasound, and magnetic resonance imaging have been used to image and diagnose diseases of the human heart. By gating the acquisition of the images to the heart cycle (gated imaging), these modalities enable one to produce 3D images of the heart without significant motion artifact and to more accurately calculate various parameters such as ejection fractions [1-3]. Unfortunately, these imaging modalities give inadequate resolution when investigating embryonic development in animal models. Defects in developmental mechanisms during embryogenesis have long been thought to result in congenital cardiac anomalies. Our understanding of normal mechanisms of heart development and how abnormalities can lead to defects has been hampered by our inability to detect anatomic and physiologic changes in these small (<2mm) organs. Optical coherence tomography (OCT) has made it possible to visualize internal structures of the living embryonic heart with high-resolution in two- and threedimensions. OCT offers higher resolution than ultrasound (30 um axial, 90 um lateral) and magnetic resonance microscopy (25 um axial, 31 um lateral) [4, 5], with greater depth penetration over confocal microscopy (200 um). Optical coherence tomography (OCT) uses back reflected light from a sample to create an image with axial resolutions ranging from 2-15 um, while penetrating 1-2 mm in depth [6]. In the past, OCT groups estimated ejection fractions using 2D images in a Xenopus laevis [7], created 3D renderings of chick embryo hearts [8], and used a gated reconstruction technique to produce 2D Doppler OCT image of an in vivo Xenopus laevis heart [9]. In this paper we present a gated imaging system that allowed us to produce a 16-frame 3D movie of a beating chick embryo heart. The heart was excised from a day two (stage 13) chicken embryo and electrically paced at 1 Hz. We acquired 2D images (B-scans) in 62.5 ms, which provides enough temporal resolution to distinguish end-contraction from end-relaxation. After acquiring the image set, we were able to measure the ejection fraction.

Proceedings Article | 1 July 2004 Paper

OCT imaging of cardiac architecture

Michael Jenkins, Florence Rothenberg, Ryan Wade, Vladimir Nikolski, Igor Efimov, Andrew Rollins, C. Pederson

Proceedings Volume 5316, (2004) https://doi.org/10.1117/12.531355

KEYWORDS: Optical coherence tomography, Heart, 3D image processing, Control systems, Tissues, In vivo imaging, Image resolution, Photography, Visualization, Frame grabbers

Read Abstract +

Showing 5 of 8 publications

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years