Dr. Igor L. Medintz Profile

Dr. Igor L. Medintz

Research Biologist at U S Naval Reserach Lab

SPIE Involvement:

Conference Program Committee | Author

Publications (54)

Proceedings Article | 18 March 2023 Presentation + Paper

Factors limiting the sensitivity of DNA-conjugated quantum dot molecular beacons

Christopher Green, Joseph Spangler, Kimihiro Susumu, David Stenger, Igor Medintz, Sebastián Díaz

Proceedings Volume 12395, 1239505 (2023) https://doi.org/10.1117/12.2649233

KEYWORDS: Quantum dot emission, Temperature metrology, Quantum DNA, Nucleic acids, Fluorescence resonance energy transfer, Fluorescence, Quantum dots, Zinc sulfide, DNA nanotechnology, Fluorescence spectroscopy

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Proceedings Article | 21 February 2020 Presentation + Paper

Considering variables in ultra-short laser pulses to release nucleic acids from the surface of gold nanoparticles

David Hastman, Igor Medintz, Sebastián Diaz

Proceedings Volume 11255, 112550C (2020) https://doi.org/10.1117/12.2544951

KEYWORDS: Gold, Pulsed laser operation, Nanoparticles, Femtosecond phenomena, Continuous wave operation, Laser systems engineering, Laser therapeutics, Optical properties, Molecules, Absorption

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Proceedings Article | 21 February 2020 Paper

Competitive binding of gold nanospheres and nanorods on DNA origami substrates

Divita Mathur, William Klein, Hieu Bui, Eunkeu Oh, Jawad Naciri, Jake Fontana, Sebastián Díaz, Igor Medintz

Proceedings Volume 11255, 1125509 (2020) https://doi.org/10.1117/12.2545953

KEYWORDS: Nanoparticles, Gold, Nanostructures, Nanorods, Nanolithography, Atomic force microscopy, Surface plasmons, Analytical research

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Proceedings Article | 13 March 2019 Presentation

Temporal multiplexing FRET: using single Tb-to-quantum dot pair distance-tuning (Conference Presentation)

Jiajia Guo, Xue Qiu, Carlos Mingoes, Jeffrey Deschamps, Igor Medintz, Niko Hildebrandt

Proceedings Volume 10892, 108920O (2019) https://doi.org/10.1117/12.2512220

KEYWORDS: Fluorescence resonance energy transfer, Multiplexing, Terbium, Biosensors

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Proceedings Article | 7 March 2019 Presentation + Paper

DNA based molecular logic devices: a review of some ongoing work with multifluorophore FRET systems

David Hastman, Sebastián Díaz, Igor Medintz

Proceedings Volume 10894, 1089416 (2019) https://doi.org/10.1117/12.2508054

KEYWORDS: Fluorescence resonance energy transfer, Logic, Logic devices, Switches, Sensors, Molecules, Nanostructures, Molecular energy transfer, Modulation, Target detection

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Proceedings Article | 7 March 2019 Presentation + Paper

Time-gated FRET from terbium labeled antibodies to quantum dot acceptors for broad ADP sensing

Sebastián Díaz, Guillermo Lasarte-Aragonés, Robert Lowery, James Vranish, William Klein, Kimihiro Susumu, Igor Medintz

Proceedings Volume 10892, 108920P (2019) https://doi.org/10.1117/12.2508626

KEYWORDS: Fluorescence resonance energy transfer, Terbium, Luminescence, Sensors, Quantum dots, Signal detection

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Proceedings Article | 15 March 2018 Presentation

Probing kinetic enhancement of β-galactosidase-nanoparticle complexes (Conference Presentation)

Joyce Breger, Anthony Malanoski, Carl Brown, Jeffery Deschamps, Kimhiro Susumu, Eunkeu Oh, George Anderson, Scott Walper, Igor Medintz

Proceedings Volume 10507, 1050709 (2018) https://doi.org/10.1117/12.2289988

KEYWORDS: Nanoparticles, Quantum dots, Systems modeling, Diffusion, Nanotechnology, Catalysis, Cell biology, Biology

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Proceedings Article | 23 February 2018 Presentation + Paper

Nanoparticle bioconjugate for controlled cellular delivery of doxorubicin

Ajmeeta Sangtani, Eleonora Petryayeva, Miao Wu, Kimihiro Susumu, Eunkeu Oh, Alan Huston, Guillermo Lasarte-Aragones, Igor Medintz, W. Russ Algar, James Delehanty

Proceedings Volume 10507, 105070M (2018) https://doi.org/10.1117/12.2290031

KEYWORDS: Toxicity, Nanoparticles, Modulation, Chemistry, Control systems, Quantum dots

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Proceedings Article | 29 August 2017 Presentation + Paper

DNA scaffold nanostructures for efficient and directional propagation of light harvesting cascades

Carl Brown, Anirban Samanta, Susan Buckhout-White, Sebastián Díaz, Scott Walper, Ellen Goldman, Igor Medintz

Proceedings Volume 10355, 1035503 (2017) https://doi.org/10.1117/12.2274639

KEYWORDS: Light harvesting, Fluorescence resonance energy transfer, Nanostructures, DNA nanotechnology, DNA photonics, Bionanoengineering, Biophotonic applications

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Proceedings Article | 22 February 2017 Presentation + Paper

Semiconductor quantum dots as Förster resonance energy transfer donors for intracellularly-based biosensors

Lauren Field, Scott Walper, Kimihiro Susumu, Eunkeu Oh, Igor Medintz, James Delehanty

Proceedings Volume 10078, 100780N (2017) https://doi.org/10.1117/12.2250899

KEYWORDS: Sensors, Quantum dots, Fluorescence resonance energy transfer, Semiconductors, Resonance energy transfer, Nanostructures, Fluorescent proteins, Biosensors, Live cell imaging, Proteins, Molecules, Optical properties

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Proceedings Article | 9 December 2016 Paper

Using DNA nanostructures to harvest light and create energy transfer and harvesting systems

Sebastián Díaz, Susan Buckhout-White, Carl Brown, Anirban Samanta, William Klein, Mario Ancona, Chris Dwyer, Ellen Goldman, Joseph Melinger, Paul Cunningham, Chris Spillmann, Igor Medintz

Proceedings Volume 10013, 1001317 (2016) https://doi.org/10.1117/12.2242727

KEYWORDS: Fluorescence resonance energy transfer, Light harvesting, Nanostructures, Energy transfer, Resonance energy transfer, Molecular photonics, Luminescence, Energy harvesting, Dendrimers, Molecules

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Proceedings Article | 28 April 2016 Presentation

Energy transfer sensitization of luminescent gold nanoclusters: more than just the classical Forster mechanism (Conference Presentation)

Eunkeu Oh, Alan Huston, Andrew Shabaev, Alexander Efros, Marc Currie, Kimihiro Susumu, Konrad Bussmann, Ramasis Goswami, Fredrik Fatemi, Igor Medintz

Proceedings Volume 9722, 97220F (2016) https://doi.org/10.1117/12.2212733

KEYWORDS: Energy transfer, Gold, Data modeling, Energy efficiency, Fluorescence resonance energy transfer, Nanocrystals, Metals, Semiconductors, Quantum dots, Nanolithography

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Proceedings Article | 22 April 2016 Presentation + Paper

The influence of cell penetrating peptide branching on cellular uptake of QDs

Joyce Breger, James Delehanty, Kimihiro Susumu, George Anderson, Markus Muttenhaler, Philip Dawson, Igor Medintz

Proceedings Volume 9722, 97220R (2016) https://doi.org/10.1117/12.2207311

KEYWORDS: Nanoparticles, Quantum dots, Semiconductors, Dendrimers, Sensors, Neptunium, Carbon dioxide, Analytical research, Luminescence, Toxicity, Tissues, Biosensing

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Proceedings Article | 22 April 2016 Presentation + Paper

Quantum dot based enzyme activity sensors present deviations from Michaelis-Menten kinetic model

Sebastián Díaz, Carl Brown, Anthony Malanoski, Eunkeu Oh, Kimihiro Susumu, Igor Medintz

Proceedings Volume 9722, 97220K (2016) https://doi.org/10.1117/12.2214235

KEYWORDS: Sensors, Quantum dots, Fluorescence resonance energy transfer, Nanosensors, Luminescence, Resonance energy transfer, Nanoparticles, Systems modeling, Calibration, Signal detection

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Proceedings Article | 12 October 2015 Presentation

Utilizing homogenous FRET to extend molecular photonic wires beyond 30 nm (Presentation Recording)

Sebastian Diaz, Susan Buckhout-White, Mario Ancona, Joseph Melinger, Igor Medintz

Proceedings Volume 9545, 95450L (2015) https://doi.org/10.1117/12.2188169

KEYWORDS: Molecular photonics, Energy transfer, Fluorescence resonance energy transfer, Energy efficiency, Luminescence, Energy harvesting, Photosynthesis, Resonance energy transfer, Nanostructures, Anisotropy

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Proceedings Article | 21 August 2015 Paper

Semiconductor quantum dots as delivery and imaging platforms for intracellular assembly

Lauren Field, James Delehanty, Scott Walper, Kimihiro Susumu, Igor Medintz

Proceedings Volume 9550, 955002 (2015) https://doi.org/10.1117/12.2188392

KEYWORDS: Fluorescence resonance energy transfer, Quantum dots, Proteins, Semiconductors, Nanolithography, Molecules, Neodymium, Visualization, Optical properties, Ions

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Proceedings Article | 21 August 2015 Presentation + Paper

Modified kinetics of enzymes interacting with nanoparticles

Sebastián Díaz, Joyce Breger, Anthony Malanoski, Jonathan Claussen, Scott Walper, Mario Ancona, Carl Brown, Michael Stewart, Eunkeu Oh, Kimihiro Susumu, Igor Medintz

Proceedings Volume 9550, 95500K (2015) https://doi.org/10.1117/12.2188212

KEYWORDS: Sensors, Fluorescence resonance energy transfer, Neptunium, Luminescence, Nanoparticles, Molecules, Catalysis, Calibration, Molecular energy transfer, Absorbance

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Proceedings Article | 13 May 2015 Paper

Enhancing enzymatic efficiency by attachment to semiconductor nanoparticles for biosensor applications

Joyce Breger, Scott Walper, Eunkeu Oh, Kimihiro Susumu, Michael Stewart, Jeffrey Deschamps, Mario Ancona, Igor Medintz

Proceedings Volume 9487, 94870S (2015) https://doi.org/10.1117/12.2180645

KEYWORDS: Nanoparticles, Biosensors, Neodymium, Metals, Absorbance, Proteins, Semiconductors, Quantum dots, Ions, Analytical research

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Proceedings Article | 12 March 2015 Paper

Membrane-targeting peptides for nanoparticle-facilitated cellular imaging and analysis

Joyce Breger, James Delehanty, Kelly Boeneman Gemmill, Lauren Field, Juan Blanco-Canosa, Philip Dawson, Alan Huston, Igor Medintz

Proceedings Volume 9338, 93381P (2015) https://doi.org/10.1117/12.2077026

KEYWORDS: Plasma, Nanoparticles, Luminescence, Analytical research, Quantum dots, Nanomaterials, Metals, Zinc, Biological research, Physiology

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Proceedings Article | 10 March 2015 Paper

Visualization and neuronal cell targeting during electrophysiological recordings facilitated by quantum dots

Lauren Field, Bertalan Andrásfalvy, Gregorio Galiñanes, Daniel Huber, Mladen Barbic, John Macklin, Kimihiro Susumu, James Delehanty, Alan Huston, Judit Makara, Igor Medintz

Proceedings Volume 9305, 93050Y (2015) https://doi.org/10.1117/12.2076934

KEYWORDS: Neurons, Visualization, Quantum dots, Plasma, Tissues, Brain, In vivo imaging, Coating, Thin film coatings, Physiology

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Proceedings Article | 27 August 2014 Paper

Controlling the intracellular fate of nano-bioconjugates: pathways for realizing nanoparticle-mediated theranostics

James Delehanty, Juan Blanco-Canosa, Christopher Bradburne, Kimihiro Susumu, Michael Stewart, Duane Prasuhn, Philip Dawson, Igor Medintz

Proceedings Volume 9166, 91660A (2014) https://doi.org/10.1117/12.2064372

KEYWORDS: Neptunium, Plasma, Nanomaterials, Proteins, Quantum dots, Gold, Nanoparticles, Imaging systems, Toxicity, Analytical research

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Proceedings Article | 28 May 2014 Paper

FRET based characterization of DNA-based assemblies

Susan Buckhout-White, Rochester Gray, Mario Ancona, Ellen Goldman, Igor Medintz

Proceedings Volume 9107, 91070Y (2014) https://doi.org/10.1117/12.2050923

KEYWORDS: Fluorescence resonance energy transfer, Anisotropy, Spectroscopy, Nanostructures, Distance measurement, Atomic force microscopy, Mica, Luminescence, Fluorescence spectroscopy, Chromophores

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Proceedings Article | 22 May 2014 Paper

Monitoring enzyme kinetic behavior of enzyme-quantum dot bioconjugates

Jonathan Claussen, Scott Walper, Kimihiro Susumu, Mario Ancona, Igor Medintz

Proceedings Volume 9107, 910710 (2014) https://doi.org/10.1117/12.2050791

KEYWORDS: Quantum dots, Nanocrystals, Metals, Semiconductors, Resistance, Quantum efficiency, Nanoparticles, In vivo imaging, Biosensing, Molecular photonics

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Proceedings Article | 1 October 2013 Paper

Enhancing molecular logic through modulation of temporal and spatial constraints with quantum dot-based systems that use fluorescent (Förster) resonance energy transfer

Jonathan Claussen, W. Russ Algar, Niko Hildebrandt, Kimihiro Susumu, Mario Ancona, Igor Medintz

Proceedings Volume 8817, 88170O (2013) https://doi.org/10.1117/12.2024287

KEYWORDS: Terbium, Logic, Fluorescence resonance energy transfer, Ultraviolet radiation, Resonance energy transfer, Modulation, Quantum dots, Luminescence, Resonance enhancement, Molecular energy transfer

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Proceedings Article | 1 October 2013 Paper

Improving energy transfer in QD-DNA photonic networks

Susan Buckhout-White, Christopher Spillmann, Mario Ancona, W. Russ Algar, Michael Stewart, Kimihiro Susumu, Alan Huston, Ellen Goldman, Igor Medintz

Proceedings Volume 8817, 88170J (2013) https://doi.org/10.1117/12.2024574

KEYWORDS: Fluorescence resonance energy transfer, Energy transfer, Chromophores, Excitons, Quantum dots, Resonance energy transfer, Thulium, Analytical research, Chemistry, Nanostructures

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Proceedings Article | 29 May 2013 Paper

Peptide-mediated cellular delivery of semiconductor quantum dots

Kelly Boeneman Gemmill, Markus Muttenthaler, James Delehanty, Jeff Deschamps, Kimihiro Susumu, Michael Stewart, Philip Dawson, Alan Huston, Igor Medintz

Proceedings Volume 8723, 872311 (2013) https://doi.org/10.1117/12.2015446

KEYWORDS: Quantum dots, Nanoparticles, Biosensing, Semiconductors, Proteins, Image analysis, Mirrors, Toxicity, Fluorescent proteins, In vitro testing

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Proceedings Article | 22 February 2013 Paper

Recent development of dihydrolipoic acid appended ligands for robust and biocompatible quantum dots

Kimihiro Susumu, Eunkeu Oh, Michael Stewart, James Delehanty, Kelly Gemmill, Vaibhav Jain, Alan Huston, Igor Medintz

Proceedings Volume 8595, 859515 (2013) https://doi.org/10.1117/12.2004952

KEYWORDS: Luminescence, Quantum dots, Proteins, Nanoparticles, Quantum efficiency, Zinc, Semiconductors, Coating, Adsorption, Biosensing

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Proceedings Article | 22 February 2013 Paper

Fluorescent nanocolloids for differential labeling of the endocytic pathway and drug delivery applications

James Delehanty, Christopher Spillmann, Jawad Naciri, W. Russ Algar, Banahalli Ratna, Igor Medintz

Proceedings Volume 8595, 85951E (2013) https://doi.org/10.1117/12.2007749

KEYWORDS: Proteins, Tissues, Nanoparticles, Iron, Biomedical optics, Quantum dots, Target recognition, Liquid crystals, Control systems, Nanomaterials

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Proceedings Article | 2 February 2012 Paper

Further progress in cytosolic cellular delivery of quantum dots

Kelly Boeneman Gemmill, James Delehanty, Michael Stewart, Kimihiro Susumu, Juan Blanco-Canosa, Philip Dawson, Alan Huston, Igor Medintz

Proceedings Volume 8232, 82320B (2012) https://doi.org/10.1117/12.906801

KEYWORDS: Quantum dots, Nanoparticles, Proteins, Biosensing, Toxicity, Luminescence, Polymers, Manufacturing, Zinc, In vivo imaging

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Proceedings Article | 12 February 2011 Paper

Quantum dots as a FRET donor and nanoscaffold for multivalent DNA photonic wires

Kelly Boeneman, Duane Prasuhn, Juan Blanco-Canosa, Philip Dawson, Joseph Melinger, Mario Ancona, Michael Stewart, Kimihiro Susumu, Alan Huston, Igor Medintz

Proceedings Volume 7909, 79090R (2011) https://doi.org/10.1117/12.879272

KEYWORDS: Fluorescence resonance energy transfer, Energy transfer, Quantum efficiency, DNA photonics, Quantum dots, Energy efficiency, Quenching (fluorescence), Composites, Chromophores, Absorption

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Proceedings Article | 5 May 2010 Paper

Quantum dots in life sciences: applications, benefits, and safety issues

James Delehanty, Christopher Bradburne, Kelly Boeneman, Kimihiro Susumu, Bing Mei, Juan Blanco-Canosa, Phillip Dawson, Hedi Mattoussi, Alan Huston, Igor Medintz

Proceedings Volume 7666, 766619 (2010) https://doi.org/10.1117/12.853121

KEYWORDS: Quantum dots, Life sciences, Safety, Semiconductors, Spectroscopy, Quantum efficiency, Polymers, Analytical research, Biology, Optical spectroscopy

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Proceedings Article | 18 February 2010 Paper

Optical size determination of quantum dots using FRET with terbium complexes as donors

D. Geißler, H.-G. Löhmannsröben, L. Charbonnière, R. Ziessel, N. Butlin, I. Medintz, H. Mattoussi, N. Hildebrandt

Proceedings Volume 7575, 75750E (2010) https://doi.org/10.1117/12.842750

KEYWORDS: Fluorescence resonance energy transfer, Luminescence, Terbium, Quantum dots, Spectroscopy, Absorption, Multiplexing, Signal detection, Semiconductors, Single molecule spectroscopy

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Proceedings Article | 18 February 2010 Paper

Delivery of quantum dot bioconjugates to the cellular cytosol: release from the endolysosomal system

James Delehanty, Christopher Bradburne, Kelly Boeneman, Igor Medintz, Dorothy Farrell, Thomas Pons, Bing Mei, Juan Blanco-Canosa, Philip Dawson, Hedi Mattoussi

Proceedings Volume 7575, 75750S (2010) https://doi.org/10.1117/12.842434

KEYWORDS: Polymers, Quantum dots, Proteins, Semiconductors, Plasma, Analytical research, Toxicity, Tissues, Sodium, Cell biology

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To realize their full potential as intracellular imaging and sensing reagents, robust and efficient methods for the targeted cellular delivery of luminescent semiconductor quantum dots (QDs) must be developed. We have previously shown that QDs decorated with histidine-terminated polyarginine cell-penetrating peptides (CPP) are rapidly and specifically internalized via endocytosis by several mammalian cell lines with no cytotoxicity. Here we demonstrate the long-term intracellular stability and fate of these QD-peptide conjugates. We found that the QD-peptide conjugates remain sequestered within endolysosomal vesicles for up to three days after delivery. However, the CPP appeared to remain stably associated with the QD within these acidic vesicles over this time period. Hence, we explored a number of techniques to either actively deliver QDs directly to the cytosol or to facilitate the endosomal release of endocytosed QDs to the cytosol. Active methods (e.g., electroporation) delivered only modest amounts of QDs to the cytosol that appeared to form aggregates. Delivery of QDs using polymer-based transfection reagents resulted primarily in the endosomal sequestration of the QDs, although one commercial polymer tested delivered QDs to the cytosol but only after several days in culture and with a considerable degree of polymer-induced toxicity. Finally, a modular, amphiphilic peptide containing functionalities designed for cell penetration and vesicular membrane interaction demonstrated the ability to deliver QDs in a well-dispersed manner to the cytosol. This peptide mediated rapid QD uptake followed by a slower efficient endosomal release of the QDs to the cytosol that peaked at 48 hours post-delivery. Importantly, this QD-peptide conjugate elicited minimal cytotoxicity in two cell lines tested. A more detailed understanding of the mechanism of the peptide's uptake and endosomal escape attributes will lead to the design of further QD conjugates for targeted imaging and sensing applications.

Proceedings Article | 3 March 2009 Paper

Intracellular delivery of and sensing with quantum dot bioconjugates

James Delehanty, Christopher Bradburne, Igor Medintz, Dorothy Farrell, Thomas Pons, Jeffrey Deschamps, Florence Brunel, Philip Dawson, Hedi Mattoussi

Proceedings Volume 7189, 71890W (2009) https://doi.org/10.1117/12.809286

KEYWORDS: Polymers, Quantum dots, Toxicity, Luminescence, Analytical research, Semiconductors, Quantum efficiency, Absorption, Multiplexing, Receptors

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Proceedings Article | 3 March 2009 Paper

Using metal complex-labeled peptides for charge transfer-based biosensing with semiconductor quantum dots

Igor Medintz, Thomas Pons, Scott Trammell, Juan Blanco-Canosa, Philip Dawson, Hedi Mattoussi

Proceedings Volume 7189, 71890M (2009) https://doi.org/10.1117/12.808537

KEYWORDS: Metals, Absorption, Ruthenium, Quantum dots, Biosensing, Semiconductors, Nanocrystals, Luminescence, Environmental sensing, Oxidation

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Proceedings Article | 3 March 2009 Paper

Multivalent display of DNA conjugates on semiconductor quantum dots utilizing a novel conjugation method

Duane Prasuhn, Juan Blanco-Canosa, Gary Vora, Hedi Mattoussi, Philip Dawson, Igor Medintz

Proceedings Volume 7189, 71890I (2009) https://doi.org/10.1117/12.808541

KEYWORDS: Quantum dots, Chemistry, Semiconductors, Atmospheric particles, Nanoparticles, Particles, Biomedical optics, Sensors, In vivo imaging, Nanocrystals

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Proceedings Article | 3 March 2009 Paper

Peptide linkers for the assembly of semiconductor quantum dot bioconjugates

Kelly Boeneman, Bing Mei, Jeffrey Deschamps, James Delehanty, Hedi Mattoussi, Igor Medintz

Proceedings Volume 7189, 71890G (2009) https://doi.org/10.1117/12.808540

KEYWORDS: Proteins, Fluorescence resonance energy transfer, Quantum dots, Semiconductors, In vitro testing, Gold, Nanolithography, Quantum efficiency, Distance measurement, Fluorescent proteins

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Proceedings Article | 19 February 2009 Paper

Energy transfer-based biosensing of protease activity measured using an electroluminescent platform

Kim Sapsford, Steven Sun, Jesse Francis, Yordan Kostov, Avraham Rasooly, Dorothy Farrell, Hedi Mattoussi, Igor Medintz

Proceedings Volume 7167, 71670X (2009) https://doi.org/10.1117/12.809301

KEYWORDS: Fluorescence resonance energy transfer, Sensors, Luminescence, Biosensing, Electroluminescence, Charge-coupled devices, Quantum dots, Semiconductors, Medicine, Bandpass filters

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Proceedings Article | 15 April 2008 Paper

Self-assembled quantum dot-bioconjugates: characterization and use for sensing proteolytic activity

Igor Medintz, Thomas Pons, Kim Sapsford, Philip Dawson, Hedi Mattoussi

Proceedings Volume 6945, 69450Q (2008) https://doi.org/10.1117/12.782174

KEYWORDS: Proteins, Luminescence, Fluorescence resonance energy transfer, Quantum dots, Semiconductors, Nanocrystals, Chemistry, Biology, Energy transfer, Biosensing

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Proceedings Article | 13 March 2008 Paper

Assembly and intracellular delivery of quantum dot-fluorescent protein bioconjugates

Igor Medintz, Thomas Pons, James Delehanty, Kimihiro Susumu, Philip Dawson, Hedi Mattoussi

Proceedings Volume 6866, 68660B (2008) https://doi.org/10.1117/12.763702

KEYWORDS: Proteins, Fluorescence resonance energy transfer, Luminescence, Quantum dots, Sensors, Nanocrystals, Fluorescent proteins, Nanolithography, Nanoparticles, Digital image correlation

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Proceedings Article | 26 February 2008 Paper

Specific cellular delivery and intracellular fate of quantum dot-peptide and quantum dot-polymer nanoassemblies

James Delehanty, Christopher Bradburne, Igor Medintz, Dorothy Farrell, Thomas Pons, Florence Brunel, Philip Dawson, Hedi Mattoussi

Proceedings Volume 6866, 68660K (2008) https://doi.org/10.1117/12.763760

KEYWORDS: Polymers, Quantum dots, Luminescence, Toxicity, Ions, Biology, Semiconductors, Biomedical optics, Spectroscopy, Metals

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Proceedings Article | 22 February 2008 Paper

New ligand design to promote water compatibility of luminescent quantum dots and gold nanoparticles

Bing Mei, Kimihiro Susumu, Igor Medintz, James Delehanty, Hedi Mattoussi

Proceedings Volume 6866, 686606 (2008) https://doi.org/10.1117/12.764267

KEYWORDS: Nanoparticles, Gold, Quantum dots, Nanocrystals, Absorption, Luminescence, Nitrogen, Sodium, Optical properties, Silica

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Proceedings Article | 27 February 2007 Paper

Quantum dot-DNA bioconjugates for fluorescence-resonance-energy-transfer-based biosensing

Igor Medintz, Lorenzo Berti, Thomas Pons, Hedi Mattoussi

Proceedings Volume 6448, 64480G (2007) https://doi.org/10.1117/12.699384

KEYWORDS: Fluorescence resonance energy transfer, Biosensing, Quantum dots, Semiconductors, Proteins, Absorption, Resonance energy transfer, Quantum efficiency, Luminescence, Analytical research

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Proceedings Article | 27 February 2007 Paper

Selective cellular delivery of self-assembled quantum dot-peptide bioconjugates

James Delehanty, Igor Medintz, Thomas Pons, Philip Dawson, Florence Brunel, Hedi Mattoussi

Proceedings Volume 6448, 64480U (2007) https://doi.org/10.1117/12.700768

KEYWORDS: Luminescence, Toxicity, Quantum dots, Control systems, Quantum efficiency, Semiconductors, Absorption, Sodium, Signal detection, Analytical research

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Proceedings Article | 27 February 2007 Paper

Single quantum dot fluorescence resonant energy transfer: probing the heterogeneity in macroscopic samples

Thomas Pons, Igor Medintz, Xiang Wang, Douglas English, Hedi Mattoussi

Proceedings Volume 6448, 64480I (2007) https://doi.org/10.1117/12.717539

KEYWORDS: Fluorescence resonance energy transfer, Proteins, Luminescence, Quantum dots, Particles, Energy transfer, Molecules, Energy efficiency, Resonance energy transfer, Absorption

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Proceedings Article | 27 March 2006 Paper

Hydrodynamic sizes of functional hydrophilic QDs

Thomas Pons, Igor Medintz, Hedi Mattoussi

Proceedings Volume 6096, 60961H (2006) https://doi.org/10.1117/12.641767

KEYWORDS: Particles, Polymers, Proteins, Diffusion, Coating, Signal detection, Quantum dots, Nanoparticles, Nanocrystals, Dynamic light scattering

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Proceedings Article | 27 March 2006 Paper

Probing the effects of spectral overlap on quantum-dot-based FRET: Ensemble and single molecule studies

Thomas Pons, Igor Medintz, Hedi Mattoussi

Proceedings Volume 6096, 60960L (2006) https://doi.org/10.1117/12.663321

KEYWORDS: Fluorescence resonance energy transfer, Absorption, Molecules, Luminescence, Nanocrystals, Proteins, Energy transfer, Semiconductors, Quantum dots, Resonance energy transfer

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Proceedings Article | 27 March 2006 Paper

Quantum-dot-based nanosensors designed for proteolytic monitoring

Igor Medintz, Aaron Clapp, Florence Brunel, Ellen Goldman, Eddie Chang, Phillip Dawson, Hedi Mattoussi

Proceedings Volume 6096, 60960K (2006) https://doi.org/10.1117/12.646199

KEYWORDS: Fluorescence resonance energy transfer, Proteins, Sensors, Nanosensors, Luminescence, Quantum dots, Absorption, Biological research, Explosives, Nanocrystals

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Proceedings Article | 27 March 2006 Paper

Quantum dot-based fluorescence resonance energy transfer multiplexing: applications for biosensing

Aaron Clapp, Igor Medintz, Hedi Mattoussi

Proceedings Volume 6096, 60960I (2006) https://doi.org/10.1117/12.647194

KEYWORDS: Fluorescence resonance energy transfer, Multiplexing, Luminescence, Proteins, Biosensing, Quantum dots, Nanosensors, Absorption, Deconvolution, Composites

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Proceedings Article | 28 April 2005 Paper

Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots

H. Uyeda, Igor Medintz, Hedi Mattoussi

Proceedings Volume 5705, (2005) https://doi.org/10.1117/12.590494

KEYWORDS: Nanocrystals, Nanoparticles, Quantum dots, Bioalcohols, Magnesium, Luminescence, Molecules, Natural surfaces, Oxides, Resistance

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Proceedings Article | 28 April 2005 Paper

A fluorescence resonance energy transfer quantum dot explosive nanosensor

Igor Medintz, Ellen Goldman, Aaron Clapp, H. Uyeda, Michael Lassman, Andrew Hayhurst, Hedi Mattoussi

Proceedings Volume 5705, (2005) https://doi.org/10.1117/12.589644

KEYWORDS: Fluorescence resonance energy transfer, Proteins, Nanosensors, Sensors, Biosensors, Analog electronics, Quantum dots, Explosives, Chemical elements, Luminescence

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Proceedings Article | 28 April 2005 Paper

Are luminescent quantum dots efficient energy acceptors?

Aaron Clapp, Igor Medintz, Brent Fisher, Hedi Mattoussi

Proceedings Volume 5705, (2005) https://doi.org/10.1117/12.590989

KEYWORDS: Fluorescence resonance energy transfer, Proteins, Luminescence, Excitons, Absorption, Time resolved spectroscopy, Quantum dots, Quantum efficiency, Energy transfer, Molecules

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Proceedings Article | 4 April 2005 Paper

Quantum-dot-based multiplexed fluorescence resonance energy transfer

Aaron Clapp, Igor Medintz, Harry Uyeda, Ellen Goldman, Hedi Mattoussi

Proceedings Volume 5704, (2005) https://doi.org/10.1117/12.591181

KEYWORDS: Fluorescence resonance energy transfer, Multiplexing, Luminescence, Proteins, Composites, Deconvolution, Absorption, Biosensors, Signal detection, Quantum dots

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Proceedings Article | 29 December 2004 Paper

Modulation of quantum dot photoemission based on fluorescence resonance energy transfer to a photochromic dye acceptor

Igor Medintz, Aaron Clapp, Scott Trammel, Hedi Mattoussi

Proceedings Volume 5593, (2004) https://doi.org/10.1117/12.570681

KEYWORDS: Fluorescence resonance energy transfer, Proteins, Ultraviolet radiation, Modulation, Surface plasmons, Quantum dots, Luminescence, Absorption, Switching, Molecules

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Showing 5 of 54 publications

Proceedings Volume Editor (1)

SPIE Conference Volume | 10 February 2006

Nanobiophotonics and Biomedical Applications III

Conference Committee Involvement (27)

Colloidal Nanoparticles for Biomedical Applications XX

25 January 2025 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XIX

27 January 2024 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XVIII

28 January 2023 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XVII

22 January 2022 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XVI

6 March 2021 | Online Only, California, United States

Colloidal Nanoparticles for Biomedical Applications XV

1 February 2020 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XIV

2 February 2019 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XIII

27 January 2018 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XII

28 January 2017 | San Francisco, California, United States

Colloidal Nanoparticles for Biomedical Applications XI

13 February 2016 | San Francisco, California, United States

Advances in Global Health through Sensing Technologies 2015

20 April 2015 | Baltimore, MD, United States

Colloidal Nanoparticles for Biomedical Applications X

7 February 2015 | San Francisco, California, United States

Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV

5 May 2014 | Baltimore, MD, United States

Colloidal Nanoparticles for Biomedical Applications IX

1 February 2014 | San Francisco, California, United States

Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring III

29 April 2013 | Baltimore, Maryland, United States

Colloidal Nanoparticles for Biomedical Applications VIII

2 February 2013 | San Francisco, California, United States

Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring II

23 April 2012 | Baltimore, Maryland, United States

Colloidal Nanocrystals for Biomedical Applications VII

21 January 2012 | San Francisco, California, United States

Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring

25 April 2011 | Orlando, Florida, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII

26 January 2011 | San Francisco, California, United States

Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense IX

5 April 2010 | Orlando, Florida, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VII

25 January 2010 | San Francisco, California, United States

Optics and Photonics in Global Homeland Security V

14 April 2009 | Orlando, Florida, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI

27 January 2009 | San Jose, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V

21 January 2008 | San Jose, California, United States

Nanoscale Imaging, Spectroscopy, Sensing and Actuation for Biomedical Applications IV

23 January 2007 | San Jose, California, United States

Nano/Biophotonics and Biomedical Applications III

23 January 2006 | San Jose, California, United States

Showing 5 of 27 Conference Committees

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