Prof. Kang Kim Profile

Prof. Kang Kim

Assistant Professor of Medicine at UPMC Presbyterian

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Author

Publications (12)

SPIE Journal Paper | 28 June 2012 Open Access

Volumetric quantification of in vitro sonothrombolysis with microbubbles using high-resolution optical coherence tomography

Jong Kim, Jonathan Leeman, Francois Yu, Xucai Chen, John Pacella, Flordeliza Villanueva, Kang Kim, Larry Kagemann, Joel Schuman

JBO, Vol. 17, Issue 7, 070502, (June 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.070502

KEYWORDS: Optical coherence tomography, Transducers, Ultrasonography, 3D image processing, In vitro testing, Cavitation, Image segmentation, In vivo imaging, Tissues, Blood

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Proceedings Article | 25 February 2012 Paper

Evaluation of finite-element-based simulation model of photoacoustics in biological tissues

Zhaohui Wang, Seunghan Ha, Kang Kim

Proceedings Volume 8320, 83201L (2012) https://doi.org/10.1117/12.912152

KEYWORDS: Tissues, Monte Carlo methods, Photoacoustic spectroscopy, Diffusion, Optical simulations, Acoustics, Signal generators, Interfaces, Signal detection, Chemical elements

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Proceedings Article | 23 February 2012 Paper

Photoacoustic design parameter optimization for deep tissue imaging by numerical simulation

Zhaohui Wang, Seunghan Ha, Kang Kim

Proceedings Volume 8223, 822346 (2012) https://doi.org/10.1117/12.912973

KEYWORDS: Tissues, Light, Tissue optics, Natural surfaces, Photoacoustic spectroscopy, Light sources, Acoustics, Laser tissue interaction, Skin, Deep tissue imaging

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Proceedings Article | 23 February 2012 Paper

Photoacoustic molecular imaging of ferritin as a reporter gene

S. Ha, A. Carson, K. Kim

Proceedings Volume 8223, 82232N (2012) https://doi.org/10.1117/12.906802

KEYWORDS: Melanoma, Molecular imaging, Luminescence, Photoacoustic spectroscopy, Iron, In vitro testing, Proteins, Transducers, Microscopy, In vivo imaging

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Proceedings Article | 18 February 2011 Paper

Multi-target photoacoustic molecular imaging of cardiovascular inflammatory biomarkers using bioconjugated gold nanorods

S. Ha, S. Tripathy, A. Carson, L. Lavery, H. Zhang, A. Agarwal, N. Kotov, F. Villanueva, K. Kim

Proceedings Volume 7899, 78991M (2011) https://doi.org/10.1117/12.875459

KEYWORDS: Ultrasonography, Injuries, Photoacoustic spectroscopy, In vivo imaging, Inflammation, Molecular imaging, Blood, Gold, Veins, Nanorods

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Proceedings Article | 28 February 2008 Paper

In vivo imaging of inflammatory responses by photoacoustics using cell-targeted gold nanorods (GNR) as contrast agent

K. Kim, A. Agarwal, A. Mcdonald, R. Moore, D. Myers, R. Witte, S.-W. Huang, S. Ashkenazi, M. Kaplan, T. Wakefield, M. O'Donnell, N. Kotov

Proceedings Volume 6856, 68560H (2008) https://doi.org/10.1117/12.763498

KEYWORDS: Injuries, Photoacoustic spectroscopy, Ultrasonography, Inflammation, Gold, Veins, Blood, Absorption, In vivo imaging, Nanorods

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Proceedings Article | 28 February 2008 Paper

Enhanced photoacoustic neuroimaging with gold nanorods and PEBBLEs

Russell Witte, K. Kim, A. Agarwal, W. Fan, R. Kopelman, N. Kotov, D. Kipke, M. O'Donnell

Proceedings Volume 6856, 685614 (2008) https://doi.org/10.1117/12.764337

KEYWORDS: Nerve, Photoacoustic spectroscopy, Tissue optics, Absorption, Gold, Neuroimaging, Brain, Tissues, In vivo imaging, Nanorods

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Proceedings Article | 13 February 2007 Paper

Contrast-enhanced photoacoustic imaging of live lobster nerve cord

Russell Witte, S. Huang, S. Ashkenazi, K. Kim, M. O'Donnell

Proceedings Volume 6437, 64370J (2007) https://doi.org/10.1117/12.701570

KEYWORDS: Photoacoustic spectroscopy, Nerve, Photoacoustic imaging, Ultrasonography, Imaging systems, Spatial resolution, Absorbance, Optical imaging, Image segmentation, Absorption

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Proceedings Article | 16 March 2006 Paper

Electric current mapping using the acousto-electric effect

Ragnar Olafsson, Russell Witte, Kang Kim, Shai Ashkenazi, Matthew O'Donnell

Proceedings Volume 6147, 61470O (2006) https://doi.org/10.1117/12.655755

KEYWORDS: Electrodes, Ultrasonography, Heart, Signal generators, Electrocardiography, Transducers, Spatial resolution, Modulation, Field programmable gate arrays, Solids

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Proceedings Article | 6 March 2006 Paper

Early detection of dental caries using photoacoustics

K. Kim, R. Witte, I. Koh, S. Ashkenazi, M. O'Donnell

Proceedings Volume 6086, 60860G (2006) https://doi.org/10.1117/12.646455

KEYWORDS: Dental caries, Photoacoustic spectroscopy, Teeth, X-rays, Radiography, Visualization, Transducers, Absorption, Photography, Pulsed laser operation

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For decades, visual, tactile and radiographic examinations have been the standard for diagnosing caries. Nonetheless, the extent of variation in the diagnosis of dental caries is substantial among dental practitioners using these traditional techniques. Therefore, a more reliable standard for detecting incipient caries would be desirable. Using photoacoustics, near-infrared (NIR) optical contrast between sound and carious dental tissues can be relatively easily and accurately detected at ultrasound resolution. In this paper, a pulsed laser (Nd:YAG, Quanta-Ray) was used to probe extracted human molars at different disease stages determined from periapical radiographs. Both fundamental (1064nm) and first harmonic (532nm) pulses (15ns pulse length, 100mJ at fundamental and 9mJ at first harmonic , 10Hz pulse repetition rate) were used to illuminate the occlusal surface of tooth samples placed in a water tank. The photoacoustic signal was recorded with an unfocused wideband single-element piezoelectric transducer (centered at 12 MHz, bandwidth 15 MHz) positioned at small angle (less than 30 degrees) to the laser beam close to the occlusal surface. At the fundamental wavelength, total photoacoustic energy increases from normal to incipient stage disease by as much as a factor of 10. Differences between photoacoustic energy at the fundamental and first harmonic wavelength further indicate spectral absorption changes of the underlying structure with disease progression. Using a focused laser beam, an extracted molar with suspected incipient caries was scanned along the occulusal surface to help localize the caries inside enamel and dentin. The significantly increasing photoacoustic signal at a specific scan line both at fundamental and first harmonic indicates the local development of the incipient caries. The photoacoustic results compare well with visual inspection after layer by layer dissection. Preliminary results demonstrate the feasibility of detecting incipient occlusal and proximal caries. This technique may ultimately allow for continuous monitoring of caries before and during treatment.

Proceedings Article | 6 March 2006 Paper

2D optoacoustic array for high resolution imaging

S. Ashkenazi, R. Witte, K. Kim, S.-W. Huang, Y. Hou, M. O'Donnell

Proceedings Volume 6086, 60861H (2006) https://doi.org/10.1117/12.645543

KEYWORDS: Fabry–Perot interferometers, Acoustics, Sensors, Ultrasonography, Signal detection, Image resolution, Polymers, Arteries, Laser beam diagnostics, Reflection

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Proceedings Article | 28 April 2004 Paper

Young's modulus reconstruction for elasticity imaging of deep venous thrombosis: animal studies

Salavat Aglyamov, Hua Xie, Kang Kim, Jonathan Rubin, Matthew O'Donnell, T. Wakefield, D. Myers, Stanislav Emelianov

Proceedings Volume 5373, (2004) https://doi.org/10.1117/12.539454

KEYWORDS: Ultrasonography, Tissues, Veins, Blood, Model-based design, Animal model studies, Arteries, Inverse problems, Surgery, Speckle

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Showing 5 of 12 publications

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