Dr. Marie-Christine A. Zdora Profile

Dr. Marie-Christine A. Zdora

at Paul Scherrer Institut

SPIE Involvement:

Conference Program Committee | Author

Proceedings Article | 14 October 2022 Open Access

Practical implementations of speckle-based phase-retrieval methods in Python and GPU for tomography

Michael Drakopoulos, Nghia Vo, Hongchang Wang, Lingfei Hu, Tunhe Zhou, Marie-Christine Zdora, Hans Deyhle, Robert Atwood

Proceedings Volume 12242, 122420E (2022) https://doi.org/10.1117/12.2636834

KEYWORDS: Speckle analysis, Phase contrast, Open source software, Tomography, X-ray imaging, Image processing

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Proceedings Article | 9 September 2021 Presentation + Paper

State of the art and recent advances in x-ray speckle-based phase-contrast imaging

Marie-Christine Zdora, Pierre Thibault, Irene Zanette

Proceedings Volume 11840, 118400S (2021) https://doi.org/10.1117/12.2595576

KEYWORDS: X-rays, X-ray imaging, Diffusers, Biomedical optics, Speckle imaging, X-ray sources, Synchrotrons, Microcomputed tomography, Phase contrast, Phase retrieval, Multimodal imaging

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Proceedings Article | 1 October 2019 Open Access

Fast Multi-scale imaging using the Beamline I13L at the Diamond Light Source

S. M. L. Schroeder, M. Loveridge, R. Ziesche, B. Connolly, C. Rau, M. Storm, S. Marathe, A. Bodey, M. Zdora, S. Cipiccia, D. Batey, X. Shi, G. Das

Proceedings Volume 11113, 111130P (2019) https://doi.org/10.1117/12.2543405

KEYWORDS: Crystals, Microscopes, X-rays, Monochromators, Mirrors, Diamond, Phase contrast, Tomography, Optical filters, Interferometry

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Proceedings Article | 1 October 2019 Open Access

New imaging opportunities at the DIAMOND beamline I13L

C. Rau, D. Batey, S. Cipiccia, X. Shi, S. Marathe, M. Storm, M. Zdora, A. Bodey

Proceedings Volume 11112, 111120L (2019) https://doi.org/10.1117/12.2543799

KEYWORDS: Sensors, Diamond, Phase contrast, Spatial resolution, Control systems, Interferometry, Mirrors, Monochromators, Image resolution, Coherence (optics)

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Proceedings Article | 11 October 2017 Open Access

Micro- and nano-tomography at the DIAMOND beamline I13L imaging and coherence

C. Rau, A. Bodey, S. Marathe, S. Cipiccia, M.-C. Zdora, I. Zanette, U. Wagner, X. Shi, D. Batey, M. Storm

Proceedings Volume 10391, 103910T (2017) https://doi.org/10.1117/12.2274514

KEYWORDS: Sensors, Diamond, Coherence imaging, Phase contrast, Coherence (optics), Spatial resolution, Microscopes, Image resolution, Tomography, CMOS sensors

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Proceedings Article | 11 October 2017 Open Access

Comparison of data processing techniques for single-grating x-ray Talbot interferometer data

Shashidhara Marathe, Marie-Christine Zdora, Irene Zanette, Silvia Cipiccia, Christoph Rau

Proceedings Volume 10391, 103910S (2017) https://doi.org/10.1117/12.2274021

KEYWORDS: Picosecond phenomena, X-rays, Spatial resolution, Interferometers, Sensors, Data processing, X-ray imaging, Image processing, Fourier transforms

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Proceedings Article | 3 October 2017 Presentation

The imaging and coherence beamline I13L at DIAMOND (Conference Presentation)

Christoph Rau, Ulrich Wagner, Malte Ogurreck, Xiaowen Shi, Darren Batey, Silvia Cipiccia, Shashidhara Marathe, Andrew Bodey, Marie-Christine Zdora, Irene Zanette, Mirna Saliba, Venkata S. Kuppili, Simone Sala, Stefanos Chalkidis, Pierre Thibault

Proceedings Volume 10389, 1038905 (2017) https://doi.org/10.1117/12.2274501

KEYWORDS: Coherence imaging, Coherence (optics), Diamond, X-rays, Spatial resolution, Microscopy, Sensors, Diffraction, Synchrotrons, Tomography

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Proceedings Article | 4 October 2016 Paper

Hierarchical imaging of the human knee

Georg Schulz, Magdalena Müller-Gerbl, Alexander Rack, Christian Götz, Hans Deyhle, Irene Zanette, Marie-Christine Zdora, Peter Thalmann, Anna Khimchenko, Bert Müller

Proceedings Volume 9967, 99670R (2016) https://doi.org/10.1117/12.2238089

KEYWORDS: Visualization, Cartilage, X-ray computed tomography, Bone, X-rays, Computed tomography, Spatial resolution, Tissues, Diamond, Light sources

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Proceedings Article | 4 October 2016 Presentation + Paper

X-ray micro-tomography for investigations of brain tissues on cellular level

Simone Hieber, Bert Müller, Peter Thalmann, Marie-Christine Zdora, Gabriel Schweighauser, Jürgen Hench, Anna Khimchenko, Georg Schulz, Hans Deyhle, Irene Zanette, Christos Bikis, Alexander Hipp

Proceedings Volume 9967, 996703 (2016) https://doi.org/10.1117/12.2237554

KEYWORDS: Tissues, Phase contrast, Visualization, X-rays, Brain, Interferometry, Absorption, Tomography, Synchrotron radiation, Cerebellum

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X-ray imaging in absorption contrast mode is well established for hard tissue visualization. However, performance for lower density materials is limited due to a reduced contrast. Our aim is three-dimensional (3D) characterization of micro-morphology of human brain tissues down to (sub-)cellular resolution within a laboratory environment. Using the laboratory-based microtomography (μCT) system nanotom m (GE Sensing and Inspection Technologies GmbH, Wunstorf, Germany) and synchrotron radiation at the Diamond-Manchester Imaging Branchline I13-2 (Diamond Light Source, Didcot, UK), we have acquired 3D data with a resolution down to 0.45 μm for visualization of a human cerebellum specimen down to cellular level. We have shown that all selected modalities, namely laboratory-based absorption contrast micro-tomography (LBμCT), synchrotron radiation based in-line single distance phase contrast tomography (SDPR) and synchrotron radiation based single-grating interferometry (GI), can reach cellular resolution for tissue samples with a size in the mm-range. The results are discussed qualitatively in comparison to optical microscopy of haematoxylin and eosin (HE) stained sections. As phase contrast yields to a better data quality for soft tissues and in order to overcome restrictions of limited beamline access for phase contrast measurements, we have equipped the μCT system nanotom m with a double-grating phase contrast set-up. Preliminary experimental results of a knee sample consisting of a bony part and a cartilage demonstrate that phase contrast data exhibits better quality compared to absorption contrast. Currently, the set-up is under adjustment. It is expected that cellular resolution would also be achieved. The questions arise (1) what would be the quality gain of laboratory-based phase contrast in comparison to laboratory-based absorption contrast tomography and (2) could laboratory-based phase contrast data provide comparable results to synchrotron radiation based phase contrast data.

Proceedings Article | 3 October 2016 Paper

Computational cell quantification in the human brain tissues based on hard x-ray phase-contrast tomograms

Georg Schulz, Hans Deyhle, Natalia Chicherova, Alexander Rack, Marie-Christine Zdora, Irene Zanette, Gabriel Schweighauser, Simone Hieber, Christos Bikis, Jürgen Hench, Bert Müller, Anna Khimchenko, Peter Thalmann

Proceedings Volume 9967, 99670K (2016) https://doi.org/10.1117/12.2237012

KEYWORDS: Tissues, Visualization, Cerebellum, Tomography, 3D image processing, Brain, Image segmentation, Edge detection, Neuroimaging, Light sources

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Showing 5 of 10 publications

Conference Committee Involvement (1)

Developments in X-Ray Tomography XV

19 August 2024 | San Diego, California, United States

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