Dr. Michael J. Daly Profile

Dr. Michael J. Daly

at Univ Health Network

SPIE Involvement:

Author

Publications (19)

SPIE Journal Paper | 11 January 2025 Open Access

Photosensitizer spatial heterogeneity and its impact on personalized interstitial photodynamic therapy treatment planning

Tina Saeidi, Shuran Wang, Hector Contreras, Michael Daly, Vaughn Betz, Lothar Lilge

JBO, Vol. 30, Issue 01, 018001, (January 2025) https://doi.org/10.1117/12.10.1117/1.JBO.30.1.018001

KEYWORDS: Picosecond phenomena, Tumors, Photodynamic therapy, Tissues, Spatial resolution, Animals, Brain, Animal model studies, Spherical lenses, Statistical analysis

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SPIE Journal Paper | 18 September 2024 Open Access

Deep learning–enabled fluorescence imaging for surgical guidance: in silico training for oral cancer depth quantification

Natalie Won, Mandolin Bartling, Josephine La Macchia, Stefanie Markevich, Scott Holtshousen, Arjun Jagota, Christina Negus, Esmat Najjar, Brian Wilson, Jonathan Irish, Michael Daly

JBO, Vol. 30, Issue S1, S13706, (September 2024) https://doi.org/10.1117/12.10.1117/1.JBO.30.S1.S13706

KEYWORDS: Tumors, Fluorescence, Education and training, Data modeling, Cancer, Fluorescence imaging, Spherical harmonics, Tissues, Optical properties, Natural surfaces

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Proceedings Article | 13 March 2024 Poster + Paper

Deep learning architectures for spatial-frequency 3D fluorescence in oral cancer surgery models

Natalie Won, Anjolaluawa Adewale, Jerry Wan, Mandolin Bartling, Jason Townson, Harley Chan, Esmat Najjar, Alon Pener-Tessler, Brian Wilson, Jonathan Irish, Michael Daly

Proceedings Volume 12825, 128250D (2024) https://doi.org/10.1117/12.3002880

KEYWORDS: Fluorescence, 3D modeling, Surgery, Cancer, Deep learning, Optical properties, Spatial frequencies

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Proceedings Article | 17 March 2023 Presentation

Deep learning-enabled fluorescence tomography in the spatial frequency domain: pre-clinical oral cancer surgery studies

Michael Daly, Scott Holtshousen, Stefanie Markevich, Arjun Jagota, Mandolin Bartling, Brian Wilson, Jonathan Irish

Proceedings Volume PC12361, PC123610A (2023) https://doi.org/10.1117/12.2650541

KEYWORDS: Fluorescence tomography, Cancer, Surgery, Luminescence, Spatial frequencies, Monte Carlo methods, Imaging systems, Animal model studies, Tumors, Data modeling

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Proceedings Article | 15 March 2023 Presentation + Paper

Proceduralist criteria for evaluating interface utility of novel imaging modalities in early phase clinical trials: evaluating the need for standardized criteria

Eric Henderson, Jonathan Elliott, Shudong Jiang, I. Leah Gitajn, John Lee, Summer Gibbs, Michael Bouvet, Anita Mahadevan-Jansen, Michael Daly, Samuel Streeter, Keith Paulsen, Brian Pogue, Kimberley Samkoe, Sunil Singhal

Proceedings Volume 12361, 123610F (2023) https://doi.org/10.1117/12.2650756

KEYWORDS: Surgery, Tissues, Target recognition, Standards development, Visualization, Medical imaging, Imaging technologies, Clinical trials, Interfaces, Fluorophores

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Proceedings Article | 15 March 2021 Presentation + Paper

Fluorescence depth estimation in pre-clinical oral cancer models using spatial frequency domain imaging

Michael Daly, Ashley Gilbank, Jacqueline Fleisig, Murtuza Rajkotwala, Shaurya Gupta, Axel Sahovaler, Donovan Eu, Marco Ferrari, Brian Wilson, Jonathan Irish

Proceedings Volume 11625, 116250C (2021) https://doi.org/10.1117/12.2577832

KEYWORDS: Luminescence, Cancer, Tumor growth modeling, 3D modeling, Tumors, Natural surfaces, Systems modeling, Monte Carlo methods, In vivo imaging

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Proceedings Article | 6 March 2020 Presentation + Paper

Image-guided fluorescence tomography in tissue phantom models of oral cancer

Michael Daly, Jacqueline Fleisig, Harley Chan, Marco Ferrari, Catriona Douglas, Brian Wilson, David Jaffray, Jonathan Irish

Proceedings Volume 11222, 112220E (2020) https://doi.org/10.1117/12.2547348

KEYWORDS: Tumors, Fluorescence tomography, Tissues, Luminescence, Natural surfaces, 3D modeling, Cancer, Visualization, Surgery, Tumor growth modeling

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Proceedings Article | 7 March 2019 Presentation + Paper

Non-contact fluorescence tomography using a cone-beam CT surgical guidance system

Michael Daly, Harley H. Chan, Nidal Muhanna, Margarete Akens, Brian Wilson, Jonathan Irish, David Jaffray

Proceedings Volume 10862, 1086206 (2019) https://doi.org/10.1117/12.2509068

KEYWORDS: Fluorescence tomography, 3D modeling, Tissue optics

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Proceedings Article | 19 February 2014 Paper

A surgical navigation system for non-contact diffuse optical tomography and intraoperative cone-beam CT

Michael Daly, Nidal Muhanna, Harley Chan, Brian Wilson, Jonathan Irish, David Jaffray

Proceedings Volume 8937, 893703 (2014) https://doi.org/10.1117/12.2040176

KEYWORDS: Imaging systems, Navigation systems, Cameras, Luminescence, Calibration, Optical tracking, Tissue optics, Liquids, Cancer, 3D image processing

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Proceedings Article | 2 March 2011 Paper

Clinical implementation of intraoperative cone-beam CT in head and neck surgery

M. Daly, H. Chan, S. Nithiananthan, J. Qiu, E. Barker, G. Bachar, B. J. Dixon, J. Irish, J. H. Siewerdsen

Proceedings Volume 7964, 796426 (2011) https://doi.org/10.1117/12.878976

KEYWORDS: Head, Surgery, Neck, 3D visualizations, Clinical trials, Endoscopy, Imaging systems, Skull, Bone, Visualization

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Proceedings Article | 3 March 2010 Paper

Fusion of intraoperative cone-beam CT and endoscopic video for image-guided procedures

M. Daly, H. Chan, E. Prisman, A. Vescan, S. Nithiananthan, J. Qiu, R. Weersink, J. Irish, J. Siewerdsen

Proceedings Volume 7625, 762503 (2010) https://doi.org/10.1117/12.844212

KEYWORDS: Endoscopy, Image registration, Endoscopes, Video, Calibration, Head, Optical tracking, Neck, Cameras, Imaging systems

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Proceedings Article | 3 March 2010 Paper

A new method of morphological comparison for bony reconstructive surgery: maxillary reconstruction using scapular tip bone

Harley Chan, Ralph Gilbert, Nitin Pagedar, Michael Daly, Jonathan Irish, Jeffrey Siewerdsen

Proceedings Volume 7625, 76253B (2010) https://doi.org/10.1117/12.845603

KEYWORDS: Bone, Surgery, 3D modeling, Computed tomography, Image segmentation, Head, Neck, Computer simulations, Image registration, Tissues

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Proceedings Article | 27 February 2010 Paper

Demons deformable registration for cone-beam CT guidance: registration of pre- and intra-operative images

S. Nithiananthan, K. Brock, M. Daly, H. Chan, J. Irish, J. Siewerdsen

Proceedings Volume 7625, 76250L (2010) https://doi.org/10.1117/12.845499

KEYWORDS: Image registration, X-ray computed tomography, Imaging systems, Head, Neck, Distortion, Computed tomography, Tissues, Reconstruction algorithms, Detection and tracking algorithms

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Proceedings Article | 13 March 2009 Paper

High-performance intraoperative cone-beam CT on a mobile C-arm: an integrated system for guidance of head and neck surgery

J. Siewerdsen, M. Daly, H. Chan, S. Nithiananthan, N. Hamming, K. Brock, J. Irish

Proceedings Volume 7261, 72610J (2009) https://doi.org/10.1117/12.813747

KEYWORDS: Surgery, Image registration, 3D image processing, Head, Neck, Imaging systems, Endoscopy, Image visualization, 3D acquisition, Video

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Proceedings Article | 13 March 2009 Paper

C-arm cone beam CT guidance of sinus and skull base surgery: quantitative surgical performance evaluation and development of a novel high-fidelity phantom

A. Vescan, H. Chan, M. Daly, I. Witterick, J. Irish, J. Siewerdsen

Proceedings Volume 7261, 72610L (2009) https://doi.org/10.1117/12.813759

KEYWORDS: Tissues, Surgery, 3D modeling, Skull, Computed tomography, 3D printing, Bone, Rapid manufacturing, Prototyping, Printing

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Proceedings Article | 21 March 2007 Paper

Multimode C-arm fluoroscopy, tomosynthesis, and cone-beam CT for image-guided interventions: from proof of principle to patient protocols

J. Siewerdsen, M. Daly, G. Bachar, D. Moseley, G. Bootsma, K. Brock, S. Ansell, G. Wilson, S. Chhabra, D. Jaffray, J. Irish

Proceedings Volume 6510, 65101A (2007) https://doi.org/10.1117/12.713642

KEYWORDS: Surgery, Image-guided intervention, Image quality, Visualization, Imaging systems, Computed tomography, X-ray computed tomography, Head, Sensors, Stereoscopy

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Proceedings Article | 2 March 2006 Paper

High-performance dual-energy imaging with a flat-panel detector: imaging physics from blackboard to benchtop to bedside

J. Siewerdsen, N. Shkumat, A. Dhanantwari, D. Williams, S. Richard, M. Daly, N. Paul, D. Moseley, D. Jaffray, J. Yorkston, R. Van Metter

Proceedings Volume 6142, 61421E (2006) https://doi.org/10.1117/12.658080

KEYWORDS: Imaging systems, Sensors, Image acquisition, Oximeters, Dual energy imaging, Lung, Radiography, Diagnostics, Silver, X-rays

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The application of high-performance flat-panel detectors (FPDs) to dual-energy (DE) imaging offers the potential for dramatically improved detection and characterization of subtle lesions through reduction of "anatomical noise," with applications ranging from thoracic imaging to image-guided interventions. In this work, we investigate DE imaging performance from first principles of image science to preclinical implementation, including: 1.) generalized task-based formulation of NEQ and detectability as a guide to system optimization; 2.) measurements of imaging performance on a DE imaging benchtop; and 3.) a preclinical system developed in our laboratory for cardiac-gated DE chest imaging in a research cohort of 160 patients. Theoretical and benchtop studies directly guide clinical implementation, including the advantages of double-shot versus single-shot DE imaging, the value of differential added filtration between low- and high-kVp projections, and optimal selection of kVp pairs, filtration, and dose allocation. Evaluation of task-based NEQ indicates that the detectability of subtle lung nodules in double-shot DE imaging can exceed that of single-shot DE imaging by a factor of 4 or greater. Filter materials are investigated that not only harden the high-kVp beam (e.g., Cu or Ag) but also soften the low-kVp beam (e.g., Ce or Gd), leading to significantly increased contrast in DE images. A preclinical imaging system suitable for human studies has been constructed based upon insights gained from these theoretical and experimental studies. An important component of the system is a simple and robust means of cardiac-gated DE image acquisition, implemented here using a fingertip pulse oximeter. Timing schemes that provide cardiac-gated image acquisition on the same or successive heartbeats is described. Preclinical DE images to be acquired under research protocol will afford valuable testing of optimal deployment, facilitate the development of DE CAD, and support comparison of DE diagnostic imaging performance to low-dose CT and radiography.

Proceedings Article | 1 September 2004 Paper

LAPS: the development of a scanning lidar system with GNC for autonomous hazard avoidance and precision landing

Jean de Lafontaine, Arkady Ulitsky, Jeffrey Tripp, Robert Richards, Michael Daly, Christian Sallaberger

Proceedings Volume 5418, (2004) https://doi.org/10.1117/12.555421

KEYWORDS: LIDAR, Mars, Safety, Sensors, Radar, Data processing, Detection and tracking algorithms, Planetary systems, Cameras, Software development

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Proceedings Article | 30 December 1999 Paper

Physico-chemical survival pattern for the radiophile D. radiodurans: a polyextremophile model for life on Mars

Robert Richmond, Raj Sridhar, Y. Zhou, Michael Daly

Proceedings Volume 3755, (1999) https://doi.org/10.1117/12.375078

KEYWORDS: Mars, Resistance, Microorganisms, Ionizing radiation, Solar radiation, Ultraviolet radiation, Hydrogen, Animal model studies, Genetic engineering, Earth's atmosphere

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Showing 5 of 19 publications

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