High-speed tracking of nano-objects is a gateway to understanding processes at the nanoscale. Here we will present our results on tracking single or ensembles of nano-objects inside optofluidic fibers and on-chip waveguides via elastic light scattering. The nano-objects diffuse inside a channel of a microstructured waveguide and the light scattered by the nano-object is detected transversely via a microscope. We will present the fundamentals of this approach and focus on selected results including 3D tracking in dual-core microstructured fibers and revealing the limits of the approach. We will also present first results on tracking inside nanoprinted on-chip waveguides.
High-speed tracking of nano-objects is a gateway to understanding biological processes at the nanoscale. Here we will present our results on tracking single or ensembles of nano-objects inside optofluidic fibers via elastic light scattering. The nano-objects diffuse inside a channel of a microstructured fiber and the light scattered by the nano-object is detected transversely via a microscope. We will present the fundamentals of this approach and focus on selected results including retrieval of the full 3D trajectory of a diffusing nano-sphere, the simultaneous detection of hundreds of nano-objects in hollow core anti-resonant fibers and first results on inactivated SARS-CoV-2.
High-speed tracking of nano-objects is a gateway to understanding biological processes at the nanoscale. Here we will present our results on tracking single or ensembles of nano-objects inside optofluidic fibers via elastic light scattering. The nano-objects diffuse inside a channel of a microstructured fiber and the light scattered by the nano-object is detected transversely via a microscope. We will present the fundamentals of this approach and focus on selected results including retrieval of the full 3D trajectory of a diffusing nano-sphere, the simultaneous detection of hundreds of nano-objects in hollow core anti-resonant fibers and first results on inactivated SARS-CoV-2.
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