For photovoltaic biointerfaces AgBiS2 quantum dots (QDs) offer favorable properties such as two-orders of magnitude higher absorption coefficient at near-infrared (NIR) in comparison with silicon for ultra-thin and flexible device formation and non-toxic material content. We demonstrate AgBiS2 QD based photovoltaic biointerface that stimulates cells within the spectral tissue transparency window by using NIR light (λ = 780 nm). The biointerface converts light energy below the ocular safety limit of light exposure to safe capacitive photocurrents that leads to reproducible action potentials on primary hippocampal neurons with high success rates.
In this work, we developed a wearable, head-mounted device that automatically calculates the precise Relative Afferent Pupillary Defect (RAPD) value of a patient. The device consists of two RGB LEDs, two infrared cameras, and one microcontroller. In the RAPD test, the parameters like LED on-off durations, brightness level, and color of the light can be controlled by the user. Upon data acquisition, a computational unit processes the data, calculates the RAPD score and visualizes the test results with a user-friendly interface. Multiprocessing methods used on GUI to optimize the processing pipeline. We have shown that our head-worn instrument is easy to use, fast, and suitable for early-diagnostics and screening purposes for various neurological conditions such as RAPD, glaucoma, asymmetric glaucoma, and anisocoria.
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