Ms. Nakisa Samadi Profile

Nakisa Samadi

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Publications (5)

Proceedings Article | 13 March 2024 Presentation

Low-cost end-user photo-thermal device for sensitive detection and quantification of analytes in fluidic samples

Derek Hayden, Baseer Yousufzai, Raha Golsorkhi, Nakisa Samadi, Nima Tabatabaei

Proceedings Volume PC12850, PC1285004 (2024) https://doi.org/10.1117/12.3001793

KEYWORDS: Statistical analysis, Gold nanoparticles, Modeling, Data modeling, COVID 19, Surface plasmons, Diseases and disorders, Design and modelling, Demodulation, Control systems

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Proceedings Article | 12 May 2022 Presentation

Handheld Point-of-Care Device for the Quantification of Anti-SARS-CoV-2 Antibodies

Damber Thapa, Nakisa Samadi, Nima Tabatabaei

Proceedings Volume PC11968, PC1196803 (2022) https://doi.org/10.1117/12.2607778

KEYWORDS: Point-of-care devices, Standards development, Thermography, Thermal sensing, Therapeutic antibodies, Plasma, Nanoparticles, Infrared sensors, Infrared radiation, Infrared imaging

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Proceedings Article | 5 March 2021 Presentation

Portable thermo-photonic device for highly sensitive detection and quantification of target analytes in lateral flow immunoassay

Damber Thapa, Nakisa Samadi, Nima Tabatabaei

Proceedings Volume 11651, 1165107 (2021) https://doi.org/10.1117/12.2580660

KEYWORDS: Target detection, Signal detection, Laser applications, Thermography, Point-of-care devices, Plasma, Particles, Nanoparticles, Infrared radiation, Gold

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Proceedings Article | 23 April 2020 Paper

Comparison of low cost and research grade active thermography platforms for detection of early dental caries

D. Thapa, N. Samadi, A. Parkhimchyk, N. Tabatabaei

Proceedings Volume 11354, 1135409 (2020) https://doi.org/10.1117/12.2555279

KEYWORDS: Dental caries, Cameras, Imaging systems, Teeth, Thermography, Infrared cameras, Image enhancement, Modulation, Phase shift keying, Optical coherence tomography

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Lock-in thermography (LIT) is a non-destructive testing technique with a broad spectrum of applications, spanning from detection of manufacturing defects in industrial samples to early diagnosis of diseases in hard and soft tissues. Nevertheless, commercialization and wide-spread adaption of LIT has long been impeded by the cost (usually $10k-$100k) and size of infrared cameras. In this paper, we demonstrate that this cost and size limitation can be overcome using cell-phone attachment infrared cameras/sensors. Developed low-cost and portable LIT systems use an intensity-modulated near infrared light for illumination while detecting thermal signatures by the low-cost cellphone attachment infrared camera (Seek thermal compact; Android). While the nominal frame rate of camera is less than 9fps, we have deciphered the communication protocol and frame information structure of the camera and set up packets of information and send them to the camera’s default endpoint address and, subsequently, acquire frame data from camera through a corresponding pipe. As such, the developed platform can control camera attributes through a simple USB interface while achieving a stable high frame rate of 33fps. To demonstrate performance of developed low-cost and portable system, two types of LIT experiments were conducted: (i) in response to the recent legalizations of marijuana in Canada, we interrogated photothermal responses of commercially available oral fluid latral flow immunoassays (LFAs), demonstrating reliable detection of THC (the psychoactive substance of cannabis) at concentrations as low as 2 ng/ml. (ii) To demonstrate ability of the system in early detection of dental caries, artificially induced early caries were created on healthy enamel surfaces and imaged with the low cost and portable system at different stages of formation. Results, suggest ability of the system in detection of caries at very early stages when neither x-ray nor visual-tactile inspection can detect them. Both sets of experiments clearly demonstrate the promise of the developed low-cost and portable LIT system in producing reliable LIT images, paving the way for translation of this technology to industry.

Proceedings Article | 13 April 2020 Presentation + Paper

Enhancement of sensitivity and detection limit of lateral flow immunoassays using lock-in thermography

D. Thapa, N. Samadi, N. Patel, N. Tabatabaei

Proceedings Volume 11361, 113610M (2020) https://doi.org/10.1117/12.2555274

KEYWORDS: Imaging systems, Thermography, Cameras, Modulation, Statistical analysis, Medicine, Image processing, Point-of-care devices, Infrared thermal wave imaging, Radiometry, Infrared imaging

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