Metamaterials are presented as a suitable platform to implement controllable constructive and destructive quantum interference. We investigate general lossy asymmetric and unbalanced 2x2 networks to realize nonclassical multiphoton interference effects. A design roadmap for achieving maximum programmability while setting a limit on the minimum value of quantum interference baseline counts is also reported. Specifically, we explore the capabilities of metasurfaces (2D alternates for metamaterials), by engineering the local interaction of light and matter at the subwavelength scale for realizing quantum interference, and conclude that metamaterials are a versatile platform for experiments on the foundations of quantum mechanics such as quantum coalescence effects.
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