Mr. Olsi Rama Profile

Olsi Rama

Project Manager at Karmanos Cancer Institute

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Publications (11)

Proceedings Article | 25 February 2012 Paper

Breast ultrasound tomography: bridging the gap to clinical practice

Neb Duric, Peter Littrup, Cuiping Li, Olivier Roy, Steven Schmidt, Roman Janer, Xiaoyang Cheng, Jeffrey Goll, Olsi Rama, Lisa Bey-Knight, William Greenway

Proceedings Volume 8320, 83200O (2012) https://doi.org/10.1117/12.910988

KEYWORDS: Breast, Prototyping, Scanners, Breast cancer, Magnetic resonance imaging, Transducers, Cancer, Ultrasound tomography, Mammography, Data acquisition

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Conventional sonography, which performs well in dense breast tissue and is comfortable and radiation-free, is not practical for screening because of its operator dependence and the time needed to scan the whole breast. While magnetic resonance imaging (MRI) can significantly improve on these limitations, it is also not practical because it has long been prohibitively expensive for routine use. There is therefore a need for an alternative breast imaging method that obviates the constraints of these standard imaging modalities. The lack of such an alternative is a barrier to dramatically impacting mortality (about 45,000 women in the US per year) and morbidity from breast cancer because, currently, there is a trade-off between the cost effectiveness of mammography and sonography on the one hand and the imaging accuracy of MRI on the other. This paper presents a progress report on our long term goal to eliminate this trade-off and thereby improve breast cancer survival rates and decrease unnecessary biopsies through the introduction of safe, cost-effective, operatorindependent sonography that can rival MRI in accuracy. The objective of the study described in this paper was to design and build an improved ultrasound tomography (UST) scanner in support of our goals. To that end, we report on a design that builds on our current research prototype. The design of the new scanner is based on a comparison of the capabilities of our existing prototype and the performance needed for clinical efficacy. The performance gap was quantified by using clinical studies to establish the baseline performance of the research prototype, and using known MRI capabilities to establish the required performance. Simulation software was used to determine the basic operating characteristics of an improved scanner that would provide the necessary performance. Design elements focused on transducer geometry, which in turn drove the data acquisition system and the image reconstruction engine specifications. The feasibility of UST established by our earlier work and that of other groups, forms the rationale for developing a UST system that has the potential to become a practical, low-cost device for breast cancer screening and diagnosis.

Proceedings Article | 26 March 2011 Paper

Breast imaging with ultrasound tomography: update on a comparative study with MR

Bryan Ranger, Peter Littrup, Neb Duric, Cuiping Li, Steven Schmidt, Olsi Rama, Lisa Bey-Knight

Proceedings Volume 7968, 79680M (2011) https://doi.org/10.1117/12.878922

KEYWORDS: Breast, Magnetic resonance imaging, Tissues, Signal attenuation, Image fusion, Visualization, Ultrasound tomography, Cancer, Image processing, Prototyping

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Proceedings Article | 25 March 2011 Paper

Double difference tomography for breast ultrasound sound speed imaging

Cuiping Li, Neb Duric, Olsi Rama, Angelika Burger, Lisa Polin, Nicole Nechiporchik

Proceedings Volume 7968, 796802 (2011) https://doi.org/10.1117/12.877559

KEYWORDS: Tomography, Breast, Ultrasonography, Mammary gland, Data acquisition, X-rays, Ultrasound tomography, Breast cancer, Inverse problems, Cancer

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Proceedings Article | 12 March 2010 Paper

Breast imaging with ultrasound tomography: a comparative study with MRI

Bryan Ranger, Peter Littrup, Neb Duric, Cuiping Li, Steven Schmidt, Jessica Lupinacci, Lukasz Myc, Amy Szczepanski, Olsi Rama, Lisa Bey-Knight

Proceedings Volume 7629, 762906 (2010) https://doi.org/10.1117/12.845650

KEYWORDS: Magnetic resonance imaging, Ultrasound tomography, Tissues, Prototyping, Breast, Tumors, Visualization, Breast imaging, Magnetism, Mammography

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Proceedings Article | 12 March 2010 Paper

Volumetric breast density evaluation by ultrasound tomography and magnetic resonance imaging: a preliminary comparative study

Lukasz Myc, Neb Duric, Peter Littrup, Cuiping Li, Bryan Ranger, Jessica Lupinacci, Steven Schmidt, Olsi Rama, Lisa Bey-Knight

Proceedings Volume 7629, 76290N (2010) https://doi.org/10.1117/12.845648

KEYWORDS: Breast, Magnetic resonance imaging, Breast cancer, Tissues, Ultrasound tomography, Mammography, Chest, Cancer, Ultrasonography, Analytical research

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Proceedings Article | 12 March 2010 Paper

In-vivo imaging results with ultrasound tomography: report on an ongoing study at the Karmanos Cancer Institute

Nebojsa Duric, Peter Littrup, Priti Chandiwala-Mody, Cuiping Li, Steven Schmidt, Lukasz Myc, Olsi Rama, Lisa Bey-Knight, Jessica Lupinacci, Bryan Ranger, Amy Szczepanski, Erik West

Proceedings Volume 7629, 76290M (2010) https://doi.org/10.1117/12.845646

KEYWORDS: Breast, Image fusion, Signal attenuation, Prototyping, Cancer, Ultrasonography, Tissues, Magnetic resonance imaging, Acoustics, Ultrasound tomography

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Proceedings Article | 12 March 2010 Paper

Monitoring breast masses with ultrasound tomography in patients undergoing neoadjuvant chemotherapy

Jessica Lupinacci, Neb Duric, Peter Littrup, Ding Wang, Cuiping Li, Steven Schmidt, Bryan Ranger, Erik West, Amy Szczepanski, Olsi Rama, Lisa Bey-Knight, Lukasz Myc

Proceedings Volume 7629, 76291C (2010) https://doi.org/10.1117/12.845647

KEYWORDS: Tumors, Breast, Breast cancer, Prototyping, Ultrasound tomography, Surgery, Magnetic resonance imaging, Cancer, Image fusion, Signal attenuation

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Proceedings Article | 21 March 2009 Paper

Detection and characterization of breast masses with ultrasound tomography: clinical results

Neb Duric, Peter Littrup, Cuiping Li, Olsi Rama, Lisa Bey-Knight, Steven Schmidt, Jessica Lupinacci

Proceedings Volume 7265, 72651G (2009) https://doi.org/10.1117/12.812994

KEYWORDS: Breast, Signal attenuation, Ultrasonography, Image fusion, Cancer, Tissues, Prototyping, Acoustics, Mammography, Magnetic resonance imaging

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Proceedings Article | 21 March 2009 Paper

Breast imaging with acoustic tomography: a comparative study with MRI

Bryan Ranger, Peter Littrup, Neb Duric, Cuiping Li, Jessica Lupinacci, Lukasz Myc, Olsi Rama, Lisa Bey-Knight

Proceedings Volume 7265, 726510 (2009) https://doi.org/10.1117/12.813350

KEYWORDS: Magnetic resonance imaging, Breast, Tissues, Acoustics, Tomography, Mammography, Prototyping, Signal attenuation, Image fusion, Cancer

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Proceedings Article | 14 March 2009 Paper

Monitoring breast masses with ultrasound tomography in patients undergoing neoadjuvant chemotherapy

Jessica Lupinacci, Neb Duric, Peter Littrup, Ding Wang, Cuiping Li, Steven Schmidt, Olsi Rama, Lisa Bey-Knight, Lukasz Myc

Proceedings Volume 7265, 726517 (2009) https://doi.org/10.1117/12.812975

KEYWORDS: Tumors, Breast, Magnetic resonance imaging, Prototyping, Breast cancer, Image fusion, Ultrasound tomography, Acoustics, Signal attenuation, Tissues

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Proceedings Article | 13 March 2009 Paper

Temperature monitoring during tissue freezing using ultrasound speed measurements

I. Jovanovic, A. Hormati, P. Littrup, N. Duric, O. Rama, M. Vetterli

Proceedings Volume 7265, 72650Q (2009) https://doi.org/10.1117/12.813682

KEYWORDS: Tissues, Reconstruction algorithms, Temperature metrology, Breast, Ultrasonography, Therapeutics, Wavelets, Tomography, Ultrasound tomography, Signal attenuation

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Showing 5 of 11 publications

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