Dr. Pablo Loza-Alvarez Profile

Dr. Pablo Loza-Alvarez

Staff researcher at ICFO - Institut de Ciències Fotòniques

SPIE Involvement:

Conference Program Committee | Author

Area of Expertise:

microscopy , light sheet microscopy , wavefront engineering , nonlinear microscopy , super resolution

Websites:

Company Website

Publications (38)

Proceedings Article | 20 June 2024 Presentation

Near infrared laser provoques focus variation in a confocal microscope

Remy Avila, Melissa Matrecitos-Avila, Reinher Pimentel-Domínguez, Elisa Tamariz, Pablo Loza-Alvarez, Edén Parra-Fuentes

Proceedings Volume PC13006, PC130060B (2024) https://doi.org/10.1117/12.3022743

KEYWORDS: Confocal microscopy, Microscopes, Near infrared, Radio optics, Integrated optics, Fluorescence intensity, Continuous wave operation, Beam path

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Proceedings Article | 3 October 2022 Presentation + Paper

Deep learning enhanced bioluminescence microscopy

Luis Felipe Morales-Curiel, Gustavo Castro-Olvera, Adriana Gonzalez, Lynn Lin, Montserrat Porta-de-la-Riva, Diego Ramallo, Pablo Loza-Alvarez, Michael Krieg

Proceedings Volume 12204, 122040B (2022) https://doi.org/10.1117/12.2632717

KEYWORDS: Microscopy, Bioluminescence, Neural networks, Luminescence, Denoising, Reconstruction algorithms, Image processing

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Proceedings Article | 1 August 2021 Presentation

ZEUS: Zernike based nEUral network for light Sheet microscopy

Laura Pérez-García, Benjamin Midtvedt, Daniel Midtvedt, Gustavo Castro-Olvera, Jordi Andilla, Pablo Loza-Alvarez, Giovanni Volpe

Proceedings Volume 11804, 118040Y (2021) https://doi.org/10.1117/12.2594022

KEYWORDS: Microscopy, Neural networks, Optical components, Photonics, Optical scanning systems, Microscopes, Luminescence, Image restoration, Image quality, High speed imaging

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Proceedings Article | 1 August 2021 Presentation

Light sheet fluorescence microscopy for 3D imaging of Ca2+ dynamics in neuronal cultures

Pablo Loza-Alvarez, Gustavo Castro-Olvera, Jorge Madrid-Wolff, Omar Olarte, Emilio Gualda, Jordi Soriano, Estefanía Estévez-Priego, Adriaan Ludl

Proceedings Volume 11804, 118040L (2021) https://doi.org/10.1117/12.2593900

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Proceedings Article | 5 March 2021 Presentation + Paper

Few-cycle all-fiber temporally coherent supercontinuum sources

Azahara Almagro-Ruiz, Salvador Torres-Peiró, Héctor Muñoz-Marco, Romain Dauliat, Raphael Jamier, Rosa Romero, Paulo Guerreiro, Marina Cunquero, Gustavo Castro, Pablo Loza-Álvarez, Helder Crespo, Philippe Roy, Pere Pérez-Millán

Proceedings Volume 11676, 116760M (2021) https://doi.org/10.1117/12.2577641

KEYWORDS: Supercontinuum sources, Dispersion, Ytterbium, Temporal coherence, Second-harmonic generation, Photonic crystal fibers, Modulation, Mode locking, Microscopy, Luminescence

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Proceedings Article | 5 March 2021 Presentation

Versatile and flexible TAOSLO device for retinal imaging

Jordi Andilla, Claudia Valdes, Nicolas Lefaudeux, Oumaima Sliti, David Merino, Xavier Levecq, Pablo Loza-Alvarez

Proceedings Volume 11633, 116330M (2021) https://doi.org/10.1117/12.2578510

KEYWORDS: Imaging devices, Retinal scanning, Visualization, Imaging systems, Image resolution, Eye, Adaptive optics, Scanning laser ophthalmoscopy, Reflectivity, Image quality

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Proceedings Article | 20 August 2020 Presentation

Light sheet microscopy for fast functional imaging of 3D neuronal cultures in hydrogels

Gustavo Castro-Olvera, Jorge Madrid-Wolff, Omar Olarte, Estefanía Estévez-Priego, Adriaan Ludl, Emilio Gualda, Laurent Ladepeche, Jordi Soriano, Pablo Loza-Alvarez

Proceedings Volume 11469, 114690C (2020) https://doi.org/10.1117/12.2567263

KEYWORDS: Microscopy, 3D image processing, Functional imaging, Luminescence, Microscopes, Neurons, Signal generators, Stereoscopy, 3D scanning, Data processing

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Proceedings Article | 1 March 2019 Presentation + Paper

Cell membrane molecular dynamics under a NIR focused laser

Remy Avila, Elisa Tamariz, Norma Medina-Villalobos, Jordi Andilla, Maria Marsal, Pablo Loza-Alvarez

Proceedings Volume 10876, 108760L (2019) https://doi.org/10.1117/12.2507904

KEYWORDS: Near infrared, Molecules, Microscopes, Confocal microscopy, Confocal fluorescent microscopy, Cell biology

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Proceedings Article | 24 April 2017 Presentation

Wavefront coding for fast, high-resolution light-sheet microscopy (Conference Presentation)

Omar Olarte, Jacob Licea-Rodriguez, Pablo Loza-Alvarez

Proceedings Volume 10073, 1007307 (2017) https://doi.org/10.1117/12.2252574

KEYWORDS: Control systems, Adaptive optics, Current controlled current source, Microscopy, Wavefronts, Stereoscopy, Microscopes, Hybrid optics, Image resolution, Photonics

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Proceedings Article | 3 March 2015 Paper

Non-linear fluorescence excitation of Rhodamine 6G and TRITC labeled IgG in whispering gallery mode microresonators

Carme Pastells, M. Pilar Marco, David Merino-Arranz, Pablo Loza-Alvarez, Laura Pasquardini, Cecilia Pederzolli, Daniele Farnesi, Simone Berneschi, Giancarlo Righini, Gualtiero Nunzi Conti, Silvia Soria Huguet

Proceedings Volume 9343, 93430K (2015) https://doi.org/10.1117/12.2079112

KEYWORDS: Luminescence, Rhodamine, Microscopes, Microresonators, Resonators, Light scattering, Absorption, Capillaries, Sensors, Confocal microscopy

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Proceedings Article | 7 March 2014 Paper

Imaging deep and clear in thick inhomogeneous samples

Jordi Andilla, Omar Olarte, Rodrigo Aviles-Espinosa, Pablo Loza-Alvarez

Proceedings Volume 8978, 89780B (2014) https://doi.org/10.1117/12.2041448

KEYWORDS: Microscopy, Optical aberrations, Monochromatic aberrations, Adaptive optics, Luminescence, Scattering, Objectives, Biology, Stereoscopy, Imaging systems

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Proceedings Article | 15 February 2012 Paper

Multiphoton imaging with compact semiconductor disk lasers

Pablo Loza-Alvarez, Rodrigo Aviles-Espinosa, David Artigas-García, Craig Hamilton, Graeme Malcolm

Proceedings Volume 8242, 82420O (2012) https://doi.org/10.1117/12.907456

KEYWORDS: Second-harmonic generation, Green fluorescent protein, Microscopes, Prototyping, Semiconductor lasers, Microscopy, Semiconductors, Image quality, Disk lasers, Photons

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Proceedings Article | 9 February 2012 Paper

Probing live samples in second-harmonic generation microscopy using specific markers and fluorescent proteins

E. De Meulenaere, R. Paesen, S. Psilodimitrakopoulos, M. Ameloot, P. Loza-Alvarez, J. Vanderleyden, K. Clays

Proceedings Volume 8226, 82263C (2012) https://doi.org/10.1117/12.907498

KEYWORDS: Second-harmonic generation, Proteins, Fluorescent proteins, Microscopy, Luminescence, Chromophores, Microscopes, Molecules, Polarization, Imaging systems

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Proceedings Article | 3 February 2012 Paper

Depth aberrations characterization in linear and nonlinear microscopy schemes using a Shack-Hartmann wavefront sensor

Rodrigo Aviles-Espinosa, Jordi Andilla, Rafael Porcar-Guezenec, Xavier Levecq, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 8227, 82271D (2012) https://doi.org/10.1117/12.907476

KEYWORDS: Microscopes, Microscopy, Adaptive optics, Monochromatic aberrations, Luminescence, Wavefront sensors, Objectives, Glasses, Interfaces, Refractive index

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Proceedings Article | 9 June 2011 Paper

Open-loop wavefront sensing scheme for specimen aberrations correction in two-photon excited fluorescence microscopy

Rodrigo Aviles-Espinosa, Jordi Andilla, Rafael Porcar-Guezenec, Xavier Levecq, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 8086, 808603 (2011) https://doi.org/10.1117/12.889397

KEYWORDS: Luminescence, Microscopes, Microscopy, Objectives, Wavefront sensors, Adaptive optics, Astronomy, Aberration correction, Calibration, Optical components

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Proceedings Article | 9 June 2011 Paper

Imaging amylopectin's order in starch using 3-dimensional polarization SHG

Sotiris Psilodimitrakopoulos, Ivan Amat-Roldan, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 8086, 80860M (2011) https://doi.org/10.1117/12.889562

KEYWORDS: Second-harmonic generation, Molecules, Polarization, 3D modeling, Crystals, Biomedical optics, Image resolution, Microscopy, Collagen, Microscopes

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Proceedings Article | 9 June 2011 Paper

Simultaneous SHG and 2PEF imaging using a new type of selective markers

E. De Meulenaere, S. Van Cleuvenbergen, S. Psilodimitrakopoulos, J. Vanderleyden, P. Loza-Alvarez, K. Clays

Proceedings Volume 8086, 80861B (2011) https://doi.org/10.1117/12.889612

KEYWORDS: Second-harmonic generation, Microscopy, Luminescence, Microscopes, Photons, Plasma, Nonlinear optics, Absorption, Optical filters, Toxicity

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Proceedings Article | 2 June 2011 Paper

Portable semiconductor disk laser for in vivo tissue monitoring: a platform for the development of clinical applications

Rodrigo Aviles-Espinosa, George Filippidis, Craig Hamilton, Graeme Malcolm, Kurt Weingarten, Thomas Südmeyer, Yohan Barbarin, Ursula Keller, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 8092, 80920R (2011) https://doi.org/10.1117/12.889400

KEYWORDS: Semiconductor lasers, Green fluorescent protein, Second-harmonic generation, Semiconductors, In vivo imaging, Laser systems engineering, Microscopy, Disk lasers, Laser applications, Laser tissue interaction

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Proceedings Article | 11 February 2011 Paper

In-vivo third-harmonic generation microscopy at 1550nm three-dimensional long-term time-lapse studies in living C. elegans embryos

Rodrigo Aviles-Espinosa, Susana I. C. Santos, Andreas Brodschelm, Wilhelm Kaenders, Cesar Alonso-Ortega, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 7904, 79041G (2011) https://doi.org/10.1117/12.874931

KEYWORDS: Tissues, Microscopy, Image processing, In vivo imaging, Fiber lasers, Time lapse microscopy, Microscopes, Signal generators, Luminescence, Third-harmonic generation

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Proceedings Article | 11 February 2011 Paper

Compact ultrafast semiconductor disk laser for nonlinear imaging in living organisms

Rodrigo Aviles-Espinosa, G. Filippidis, Craig Hamilton, Graeme Malcolm, Kurt Weingarten, Thomas Südmeyer, Yohan Barbarin, Ursula Keller, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 7903, 79032T (2011) https://doi.org/10.1117/12.874865

KEYWORDS: Green fluorescent protein, Second-harmonic generation, Semiconductor lasers, Semiconductors, Disk lasers, Laser applications, Laser systems engineering, Mirrors, Pulsed laser operation, Microscopes

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Proceedings Article | 11 February 2011 Paper

Three-dimensional polarization second harmonic generation (3D-PSHG) imaging: the effect of the tilted-off the plane SHG active structures

Sotiris Psilodimitrakopoulos, Ivan Amat-Roldan, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 7903, 79030H (2011) https://doi.org/10.1117/12.875254

KEYWORDS: Second-harmonic generation, 3D modeling, Polarization, Molecules, Harmonic generation, Collagen, 3D image processing, Objectives, Statistical modeling, 3D acquisition

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Proceedings Article | 17 January 2011 Paper

High-sensitive nonlinear detection of steroids by resonant double grating waveguide structures-based immunosensors

Alejandro Muriano, J.-Pablo Salvador, Roger Galve, M.-Pilar Marco, Anisha Thayil K.N., Pablo Loza-Alvarez, Silvia Soria

Proceedings Volume 7941, 794114 (2011) https://doi.org/10.1117/12.876456

KEYWORDS: Waveguides, Tantalum, Signal detection, Luminescence, Polarization, Diffraction gratings, Silica, Receptors, Fluorescence spectroscopy, Sensors

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Proceedings Article | 14 October 2010 Paper

Designing supercontinuum spectra using Grid technology

A. Ferrando, C. Milián, N. González, G. Moltó, P. Loza, M. Arevalillo-Herráez, M. Zacarés, I. Torres-Gómez, V. Hernández

Proceedings Volume 7839, 78390W (2010) https://doi.org/10.1117/12.867203

KEYWORDS: Genetic algorithms, Optimization (mathematics), Computer simulations, Dispersion, Terahertz radiation, Photonic devices, Photonic crystal fibers, Standards development, Distributed computing, Microscopy

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SPIE Journal Paper | 1 July 2010 Open Access

Third-harmonic generation for the study of Caenorhabditis elegans embryogenesis

Rodrigo Aviles-Espinosa, Susana Santos, Andreas Brodschelm, Wilhelm Kaenders, Cesar Alonso-Ortega, David Artigas-García, Pablo Loza-Alvarez

JBO, Vol. 15, Issue 04, 046020, (July 2010) https://doi.org/10.1117/12.10.1117/1.3477535

KEYWORDS: Microscopy, Third-harmonic generation, Tissues, 3D image processing, In vivo imaging, Image processing, Fiber lasers, Interfaces, Signal processing, Video

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Proceedings Article | 18 May 2010 Paper

Assessing structural characteristics of axons in cortical neurons using polarization sensitive SHG

Sotiris Psilodimitrakopoulos, Valerie Petegnief, Guadalupe Soria, Nuria de Vera, Ivan Amat-Roldan, David Artigas, Anna Planas, Pablo Loza-Alvarez

Proceedings Volume 7715, 77152A (2010) https://doi.org/10.1117/12.854642

KEYWORDS: Second-harmonic generation, Polarization, Neurons, Axons, Collagen, Objectives, Linear filtering, Molecules, Microscopes, Optical filters

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Proceedings Article | 18 May 2010 Paper

Optical extraction of the helical pitch angle of amylopectin in starch

Sotiris Psilodimitrakopoulos, Ivan Amat-Roldan, Pablo Loza-Alvarez, David Artigas

Proceedings Volume 7715, 771529 (2010) https://doi.org/10.1117/12.854629

KEYWORDS: Second-harmonic generation, Molecules, Polarization, Collagen, Microscopes, Objectives, Harmonic generation, Image resolution, Scattering, Crystals

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Proceedings Article | 26 February 2010 Paper

Polarization second harmonic generation (PSHG) imaging of neurons: estimating the effective orientation of the SHG source in axons

Sotiris Psilodimitrakopoulos, Valerie Petegnief, Guadalupe Soria, Ivan Amat-Roldan, David Artigas, Anna Planas, Pablo Loza-Alvarez

Proceedings Volume 7569, 75692W (2010) https://doi.org/10.1117/12.841313

KEYWORDS: Second-harmonic generation, Polarization, Neurons, Axons, Collagen, Harmonic generation, Microscopy, Signal processing, In vitro testing, Objectives

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Proceedings Article | 24 February 2010 Paper

Practical optical quality assessment and correction of a nonlinear microscope

Rodrigo Aviles-Espinosa, Jordi Andilla, Rafael Porcar-Guezenec, Omar Olarte, Susana I.C. Santos, Xavier Levecq, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 7570, 75700W (2010) https://doi.org/10.1117/12.840978

KEYWORDS: Microscopes, Objectives, Adaptive optics, Nonlinear optics, Microscopy, Calibration, Wavefront sensors, Luminescence, Wavefronts, Optical components

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Proceedings Article | 1 July 2009 Paper

Myosin helical pitch angle as a quantitative imaging biomarker for characterization of cardiac programming in fetal growth restriction measured by polarization second harmonic microscopy

I. Amat-Roldan, S, Psilodimitrakopoulos, E, Eixarch, I. Torre, B. Wotjas, F. Crispi, F. Figueras, D, Artigas, P. Loza-Alvarez, E, Gratacos

Proceedings Volume 7367, 73670O (2009) https://doi.org/10.1117/12.831481

KEYWORDS: Computer programming, Polarization, Microscopy, Statistical analysis, Tissues, Microscopes, Heart, Diagnostics, Second-harmonic generation, Fetus

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Proceedings Article | 1 July 2009 Paper

Contrast enhancement in second harmonic imaging: discriminating between muscle and collagen

Sotiris Psilodimitrakopoulos, David Artigas, Guadalupe Soria, Ivan Amat-Roldan, Iratxe Torre, Eduard Gratacos, Anna Planas, Pablo Loza-Alvarez

Proceedings Volume 7367, 73670S (2009) https://doi.org/10.1117/12.831487

KEYWORDS: Collagen, Second-harmonic generation, Polarization, Tissues, Microscopy, Luminescence, Harmonic generation, Pixel resolution, Tongue, Image filtering

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SPIE Journal Paper | 1 January 2009 Open Access

In vivo, pixel-resolution mapping of thick filaments' orientation in nonfibrilar muscle using polarization-sensitive second harmonic generation microscopy

Sotiris Psilodimitrakopoulos, Susana I. Santos, Ivan Amat-Roldán, Anisha Thayil Karunakaran Nair, David Artigas-García, Pablo Loza-Alvarez

JBO, Vol. 14, Issue 01, 014001, (January 2009) https://doi.org/10.1117/12.10.1117/1.3059627

KEYWORDS: Second-harmonic generation, Polarization, In vivo imaging, Signal detection, Molecules, Microscopy, Harmonic generation, Image analysis, Microscopes, Nonlinear optics

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Proceedings Article | 12 March 2008 Paper

Starch granules as a probe for the polarization at the sample plane of a high resolution multiphoton microscope

Sotiris Psilodimitrakopoulos, Ivan Amat-Roldan, Susana Santos, Manoj Mathew, Anisha Thayil K. N., Dobryna Zalvidea, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 6860, 68600E (2008) https://doi.org/10.1117/12.763168

KEYWORDS: Polarization, Second-harmonic generation, Signal detection, Molecules, Microscopes, Crystals, Polarizers, Signal generators, Objectives, Microscopy

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Proceedings Article | 15 February 2008 Paper

Polarization dependant in vivo second harmonic generation imaging of Caenorhabditis elegans vulval, pharynx, and body wall muscles

Sotiris Psilodimitrakopoulos, Susana Santos, Ivan Amat-Roldan, Manoj Mathew, Anisha Thayil K. N., David Artigas, Pablo Loza-Alvarez

Proceedings Volume 6860, 686008 (2008) https://doi.org/10.1117/12.763270

KEYWORDS: Second-harmonic generation, Polarization, In vivo imaging, Image resolution, Signal detection, Harmonic generation, Tissues, Collagen, Nonlinear optics, Data modeling

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Proceedings Article | 15 February 2008 Paper

Two-photon fluorescence imaging and femtosecond laser microsurgery to study drosophila dorsal closure

Anisha Thayil K. N., Andrea Pereira, Manoj Mathew, David Artigas, Enrique Martín Blanco, Pablo Loza-Alvarez

Proceedings Volume 6860, 68601Z (2008) https://doi.org/10.1117/12.762741

KEYWORDS: Tissues, Femtosecond phenomena, Laser ablation, Wound healing, Fusion energy, Luminescence, Microsurgery, Absorption, Two photon imaging, Microscopes

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Proceedings Article | 19 February 2007 Paper

Ultra-short pulses to signal neuronal growth cone machinery

Manoj Mathew, Ivan Amat-Roldan, Rosa Andres, Iain Cormack, David Artigas, Eduardo Soriano, Pablo Loza-Alvarez

Proceedings Volume 6441, 64410G (2007) https://doi.org/10.1117/12.699988

KEYWORDS: Neurons, Statistical analysis, Continuous wave operation, Femtosecond phenomena, Axons, Pulsed laser operation, Microscopes, Sensors, Mirrors

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Proceedings Article | 10 February 2007 Paper

Backward second-harmonic generation from starch for in-situ real-time pulse characterization in multiphoton microscopy

Anisha Thayil Karunakaran Nair, Emilio Gualda, Iain Cormack, Silvia Soria, Pablo Loza-Alvarez

Proceedings Volume 6442, 64421S (2007) https://doi.org/10.1117/12.700222

KEYWORDS: Second-harmonic generation, Microscopes, Luminescence, Multiphoton microscopy, Interferometry, Objectives, Spectroscopy, Signal detection, Ultrafast phenomena, Green fluorescent protein

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Proceedings Article | 20 April 2006 Paper

Two-photon photoluminescence spectroscopy of metal dimers

Petru Ghenuche, Daniel ten Bloemendal, Romain Quidant, Iain Cormack, Pablo Loza-Alvarez, Gonçal Badenes

Proceedings Volume 6195, 619502 (2006) https://doi.org/10.1117/12.661856

KEYWORDS: Luminescence, Polarization, Scattering, Particles, Spectroscopy, Metals, Near field, Gold, Near field optics, Nanostructures

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Proceedings Article | 8 September 2004 Paper

Nonlinear microscopy pulse optimization at the sample plane using second-harmonic generation from starch

Ivan Amat-Roldan, Iain Cormack, David Artigas, Pablo Loza-Alvarez

Proceedings Volume 5463, (2004) https://doi.org/10.1117/12.545910

KEYWORDS: Objectives, Ultrafast phenomena, Microscopes, Second-harmonic generation, Microscopy, Interferometry, Nonlinear crystals, Polarization, Luminescence, Sensors

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Showing 5 of 38 publications

Conference Committee Involvement (16)

Emerging Topics in Artificial Intelligence (ETAI) 2025

3 August 2025 | San Diego, California, United States

Adaptive Optics and Wavefront Control for Biological Systems XI

26 January 2025 | San Francisco, California, United States

Emerging Topics in Artificial Intelligence (ETAI) 2024

18 August 2024 | San Diego, California, United States

Adaptive Optics and Wavefront Control for Biological Systems X

28 January 2024 | San Francisco, California, United States

Emerging Topics in Artificial Intelligence (ETAI) 2023

20 August 2023 | San Diego, California, United States

Adaptive Optics and Wavefront Control for Biological Systems IX

29 January 2023 | San Francisco, California, United States

Emerging Topics in Artificial Intelligence (ETAI) 2022

21 August 2022 | San Diego, California, United States

Adaptive Optics and Wavefront Control for Biological Systems VIII

24 January 2022 | San Francisco, California, United States

Emerging Topics in Artificial Intelligence (ETAI) 2021

1 August 2021 | San Diego, California, United States

Adaptive Optics and Wavefront Control for Biological Systems VII

6 March 2021 | Online Only, California, United States

Adaptive Optics and Wavefront Control for Biological Systems VI

2 February 2020 | San Francisco, California, United States

Adaptive Optics and Wavefront Control for Biological Systems V

3 February 2019 | San Francisco, California, United States

Adaptive Optics and Wavefront Control for Biological Systems IV

27 January 2018 | San Francisco, California, United States

Adaptive Optics and Wavefront Control for Biological Systems III

28 January 2017 | San Francisco, California, United States

Adaptive Optics and Wavefront Control for Biological Systems II

13 February 2016 | San Francisco, California, United States

Adaptive Optics and Wavefront Control for Biological Systems

7 February 2015 | San Francisco, California, United States

Showing 5 of 16 Conference Committees

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