Dr. Peijun Gong Profile

Dr. Peijun Gong

Research Associate at Univ of Western Australia

SPIE Involvement:

Editorial Board Member: Biophotonics Discovery | Author

Publications (15)

SPIE Journal Paper | 6 December 2023 Open Access

In vivo burn scar assessment with speckle decorrelation and joint spectral and time domain optical coherence tomography

Qiang Wang, Peijun Gong, Hadi Afsharan, Chulmin Joo, Natalie Morellini, Mark Fear, Fiona Wood, Hao Ho, Dilusha Silva, Barry Cense

JBO, Vol. 28, Issue 12, 126001, (December 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.12.126001

KEYWORDS: Blood vessels, Tissues, Optical coherence tomography, Skin, Speckle, In vivo imaging, Blood circulation, Velocity measurements, Capillaries, Biological imaging

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Proceedings Article | 9 March 2023 Presentation

In vivo quantitative micro-elastography for detection of residual cancer during breast-conserving surgery

Peijun Gong, Synn Lynn Chin, Wes Allen, Helen Ballal, James Anstie, Lixin Chin, Hina Ismail, Renate Zilkens, Devina Lakhiani, Matthew McCarthy, Qi Fang, Daniel Firth, Kyle Newman, Caleb Thomas, Jiayue Li, Rowan Sanderson, Ken Foo, Chris Yeomans, Benjamin Dessauvagie, Bruce Latham, Christobel Saunders, Brendan Kennedy

Proceedings Volume PC12367, PC1236715 (2023) https://doi.org/10.1117/12.2652919

KEYWORDS: In vivo imaging, Cancer, Surgery, Breast cancer, Elastography, Coherence (optics)

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Proceedings Article | 6 March 2023 Presentation

In-cavity detection of residual cancer during breast-conserving surgery using in vivo quantitative micro-elastography

Proceedings Volume PC12368, PC1236804 (2023) https://doi.org/10.1117/12.2651033

KEYWORDS: Cancer, Surgery, In vivo imaging, Breast cancer, Tissues, Diagnostics, Breast, Visualization

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SPIE Journal Paper | 15 September 2020 Open Access

Detection of localized pulsatile motion in cutaneous microcirculation by speckle decorrelation optical coherence tomography angiography

Peijun Gong, Christian Heiss, Danuta Sampson, Qiang Wang, Zhihong Yuan, David Sampson

JBO, Vol. 25, Issue 09, 095004, (September 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.9.095004

KEYWORDS: Tissues, Optical coherence tomography, Skin, Speckle, Natural surfaces, Oximeters, Motion measurement, Blood circulation, Blood vessels, Visualization

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SPIE Journal Paper | 3 April 2020 Open Access

Parametric imaging of attenuation by optical coherence tomography: review of models, methods, and clinical translation

Peijun Gong, Mitra Almasian, Gijs van Soest, Daniel de Bruin, Ton van Leeuwen, David Sampson, Dirk Faber

JBO, Vol. 25, Issue 04, 040901, (April 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.4.040901

KEYWORDS: Optical coherence tomography, Signal attenuation, Tissues, Scattering, Tissue optics, Light scattering, Skin, Optical properties, Absorption, Cancer

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Proceedings Article | 29 April 2017 Paper

Axial length variation impacts on retinal vessel density and foveal avascular zone area measurement using optical coherence tomography angiography

Danuta Sampson, Peijun Gong, Di An, Moreno Menghini, Alex Hansen, David Mackey, David Sampson, Fred Chen

Proceedings Volume 10340, 1034017 (2017) https://doi.org/10.1117/12.2270134

KEYWORDS: Optical coherence tomography, Angiography, Biomedical optics, Databases, Ischemia, Vascular diseases, Imaging systems, Eye, Capillaries, Ophthalmology, Retina, Medical research, Visual analytics, Visualization

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Proceedings Article | 29 April 2017 Paper

Ex-vivo imaging of blood and lymphatic vessels in conjunctiva using optical coherence tomography

Peijun Gong, Karol Karnowski, Paula Yu, Dong An, Dao-Yi Yu, David Sampson

Proceedings Volume 10340, 1034018 (2017) https://doi.org/10.1117/12.2270180

KEYWORDS: Optical coherence tomography, Lymphatic system, Blood, In vivo imaging, Blood vessels, Signal attenuation, Scattering, Angiography, Eye, Biomedical optics, Surgery, Visualization, Tissues, Optic nerve

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Proceedings Article | 19 April 2017 Presentation

Ex vivo and in vivo label-free imaging of lymphatic vessels using OCT lymphangiography (Conference Presentation)

Peijun Gong, Shaghayegh Es’haghian, Karol Karnowski, Suzanne Rea, Fiona Wood, Dao-Yi Yu, Robert McLaughlin, David Sampson

Proceedings Volume 10053, 100531I (2017) https://doi.org/10.1117/12.2254935

KEYWORDS: Image processing algorithms and systems, Laser ablation, Optical coherence tomography, Lymphatic system, In vivo imaging, Signal attenuation, Transparency, Confocal microscopy, Image processing, Image segmentation

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Proceedings Article | 26 April 2016 Presentation

Parametric approaches to micro-scale characterization of tissue volumes in vivo and ex vivo: Imaging microvasculature, attenuation, birefringence, and stiffness (Conference Presentation)

David Sampson, Lixin Chin, Peijun Gong, Philip Wijesinghe, Shaghayegh Es’haghian, Wesley Allen, Blake Klyen, Rodney Kirk, Brendan Kennedy, Robert McLaughlin

Proceedings Volume 9703, 97030M (2016) https://doi.org/10.1117/12.2218719

KEYWORDS: Tissues, Optical coherence tomography, Tissue optics, Birefringence, Tumors, In vivo imaging, Signal attenuation, Cancer, Microscopy, Medical imaging

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Proceedings Article | 6 March 2015 Paper

In vivo optical elastography: stress and strain imaging of human skin lesions

Shaghayegh Es'haghian, Peijun Gong, Kelsey Kennedy, Philip Wijesinghe, David Sampson, Robert McLaughlin, Brendan Kennedy

Proceedings Volume 9327, 93270C (2015) https://doi.org/10.1117/12.2078706

KEYWORDS: Skin, Tissue optics, Optical coherence tomography, Sensors, In vivo imaging, Interfaces, Elastography, Image compression, Pathology, Photography

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SPIE Journal Paper | 14 January 2015 Open Access

Optical palpation in vivo: imaging human skin lesions using mechanical contrast

Shaghayegh Es’haghian, Kelsey Kennedy, Peijun Gong, David Sampson, Robert McLaughlin, Brendan Kennedy

JBO, Vol. 20, Issue 01, 016013, (January 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.1.016013

KEYWORDS: Skin, Sensors, Tissue optics, Optical coherence tomography, In vivo imaging, Biomedical optics, Interfaces, Silicon, Image compression, Tissues

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SPIE Journal Paper | 24 December 2014 Open Access

Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking

Peijun Gong, Lixin Chin, Shaghayegh Es’haghian, Yih Miin Liew, Fiona Wood, David Sampson, Robert McLaughlin

JBO, Vol. 19, Issue 12, 126014, (December 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.12.126014

KEYWORDS: Birefringence, Skin, Collagen, Tissue optics, Tissues, Optical coherence tomography, Blood vessels, Optical fibers, Polarization, In vivo imaging

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SPIE Journal Paper | 5 November 2013 Open Access

Assessment of human burn scars with optical coherence tomography by imaging the attenuation coefficient of tissue after vascular masking

Peijun Gong, Robert McLaughlin, Yih Miin Liew, Peter Munro, Fiona Wood, David Sampson

JBO, Vol. 19, Issue 02, 021111, (November 2013) https://doi.org/10.1117/12.10.1117/1.JBO.19.2.021111

KEYWORDS: Signal attenuation, Skin, Optical coherence tomography, Tissues, Tissue optics, Collagen, Scattering, Blood vessels, Coherence imaging, Water

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SPIE Journal Paper | 19 December 2012 Open Access

Errata: In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography

Yih Miin Liew, Robert McLaughlin, Peijun Gong, Fiona Wood, David Sampson

JBO, Vol. 18, Issue 06, 069801, (December 2012) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.069801

KEYWORDS: In vivo imaging, Optical coherence tomography, Photography, Skin, Biomedical optics, Tissue optics, Blood vessels, Electronics engineering, Computer engineering, Biomedical engineering

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This article [J. Biomed. Opt.. 18, , 061213 (2013)] was originally published online on 22 November 2012 with an error in the caption of Fig. 7. In the first line, the word “hypertrophic” should be “normotrophic.” The corrected caption reads as follows: Case Study 4. (a) Photograph of a 12-month-old normotrophic scar due to a flame burn on the left lateral forearm. The extent of the scar is outlined in dotted green. The photograph of the contralateral normal skin is not shown. (b) and (c) are the en face MIPs of the vasculature in scar tissue and contralateral normal skin, respectively. The vasculature in (b) and (c) is color-coded by physical depth (μm) in (d) and (e), respectively. Histograms of blood vessel diameter measurements and other quantification results are shown in (f). Scale bar indicates a distance of 0.5 mm.

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SPIE Journal Paper | 22 November 2012

In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography

Yih Miin Liew, Robert McLaughlin, Peijun Gong, Fiona Wood, David Sampson

JBO, Vol. 18, Issue 06, 061213, (November 2012) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.061213

KEYWORDS: Skin, Optical coherence tomography, Tissues, In vivo imaging, Speckle, Blood vessels, Natural surfaces, Injuries, 3D image processing, Photography

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In scars arising from burns, objective assessment of vascularity is important in the early identification of pathological scarring, and in the assessment of progression and treatment response. We demonstrate the first clinical assessment and automated quantification of vascularity in cutaneous burn scars of human patients in vivo that uses optical coherence tomography (OCT). Scar microvasculature was delineated in three-dimensional OCT images using speckle decorrelation. The diameter and area density of blood vessels were automatically quantified. A substantial increase was observed in the measured density of vasculature in hypertrophic scar tissues (38%) when compared against normal, unscarred skin (22%). A proliferation of larger vessels (diameter≥100 μm) was revealed in hypertrophic scarring, which was absent from normal scars and normal skin over the investigated physical depth range of 600 μm. This study establishes the feasibility of this methodology as a means of clinical monitoring of scar progression.

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