Dr. Peter H. Tomlins Profile

Dr. Peter H. Tomlins

Senior Lecturer at Queen Mary Univ of London

SPIE Involvement:

Author

Publications (18)

Proceedings Article | 13 February 2018 Presentation + Paper

Heart rate sensitive optical coherence angiography

Karl Alvarez, Jordi Lopez-Tremoleda, Rob Donnan, Adina Michael-Titus, Peter Tomlins

Proceedings Volume 10493, 104930G (2018) https://doi.org/10.1117/12.2317602

KEYWORDS: Modulation, Optical coherence tomography, Beam propagation method, Scattering, Heart, Angiography, Coherence (optics), In vivo imaging, Tissues, Tissue optics

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SPIE Journal Paper | 5 December 2017 Open Access

Heart-rate sensitive optical coherence angiography for measuring vascular changes due to posttraumatic brain injury in mice

Jordi L. Tremoleda, Karl Alvarez, Abdirahman Aden, Robert Donnan, Adina T. Michael-Titus, Peter H. Tomlins

JBO, Vol. 22, Issue 12, 121710, (December 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.12.121710

KEYWORDS: Traumatic brain injury, Optical coherence tomography, Tissues, Angiography, Coherence (optics), Injuries, Heart, Tissue optics, Skull, Brain

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SPIE Journal Paper | 31 July 2017 Open Access

Dynamic measurement of the optical properties of bovine enamel demineralization models using four-dimensional optical coherence tomography

Abdirahman Aden, Arthi Anthony, Carel Brigi, Muhammad Merchant, Huda Siraj, Peter Tomlins

JBO, Vol. 22, Issue 07, 076020, (July 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.7.076020

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Dental enamel mineral loss is multifactorial and is consequently explored using a variety of in vitro models. Important factors include the presence of acidic pH and its specific ionic composition, which can both influence lesion characteristics. Optical coherence tomography (OCT) has been demonstrated as a promising tool for studying dental enamel demineralization. However, OCT-based characterization and comparison of demineralization model dynamics are challenging without a consistent experimental environment. Therefore, an automated four-dimensional OCT system was integrated with a multispecimen flow cell to measure and compare the optical properties of subsurface enamel demineralization in different models. This configuration was entirely automated, thus mitigating any need to disturb the specimens and ensuring spatial registration of OCT image volumes at multiple time points. Twelve bovine enamel disks were divided equally among three model groups. The model demineralization solutions were citric acid (pH 3.8), acetic acid (pH 4.0), and acetic acid with added calcium and phosphate (pH 4.4). Bovine specimens were exposed to the solution continuously for 48 h. Three-dimensional OCT data were obtained automatically from each specimen at a minimum of 1-h intervals from the same location within each specimen. Lesion dynamics were measured in terms of the depth below the surface to which the lesion extended and the attenuation coefficient. The net loss of surface enamel was also measured for comparison. Similarities between the dynamics of each model were observed, although there were also distinct characteristic differences. Notably, the attenuation coefficients showed a systematic offset and temporal shift with respect to the different models. Furthermore, the lesion depth curves displayed a discontinuous increase several hours after the initial acid challenge. This work demonstrated the capability of OCT to distinguish between different enamel demineralization models by making dynamic quantitative measurements of lesion properties. This has important implications for future applications in clinical dentistry.

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SPIE Journal Paper | 1 April 2016 Open Access

Dynamic measurement of local displacements within curing resin-based dental composite using optical coherence elastography

Peter Tomlins, Mohammed Wahidur Rahman, Robert Donnan

JBO, Vol. 21, Issue 04, 046001, (April 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.4.046001

KEYWORDS: Glasses, Composites, Optical coherence tomography, Composite resins, Coherence (optics), Elastography, Polymerization, Point spread functions, Dentistry, Lamps

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Proceedings Article | 13 March 2013 Paper

Multi-system comparison of optical coherence tomography performance with point spread function phantoms

Joshua Pfefer, Anthony Fouad, Chao-Wei Chen, Wei Gong, Peter Tomlins, Peter Woolliams, Rebekah Drezek, Anant Agrawal, Yu Chen

Proceedings Volume 8573, 85730C (2013) https://doi.org/10.1117/12.2007005

KEYWORDS: Point spread functions, Optical coherence tomography, Particles, Silica, Spatial resolution, Gold, Image quality standards, Optical resolution, Image quality, Backscatter

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Proceedings Article | 3 February 2012 Paper

Three-dimensional calibration targets for optical coherence tomography

Michelle Gabriele Sandrian, Pete Tomlins, Peter Woolliams, Janarthanan Rasakanthan, Graham Lee, Anna Yang, Boris Považay, Aneesh Alex, Kate Sugden, Wolfgang Drexler

Proceedings Volume 8229, 822914 (2012) https://doi.org/10.1117/12.907748

KEYWORDS: Optical coherence tomography, Calibration, Nanoparticles, Point spread functions, 3D acquisition, Femtosecond phenomena, Particles, 3D metrology, Iron, Oxides

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SPIE Journal Paper | 1 February 2011 Open Access

Processing and rendering of Fourier domain optical coherence tomography images at a line rate over 524 kHz using a graphics processing unit

Janarthanan Rasakanthan, Kate Sugden, Peter Tomlins

JBO, Vol. 16, Issue 02, 020505, (February 2011) https://doi.org/10.1117/12.10.1117/1.3548153

KEYWORDS: Optical coherence tomography, Data processing, Image processing, Graphics processing units, Signal detection, Computer programming, Spectroscopy, Visualization, Data acquisition, MATLAB

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SPIE Journal Paper | 1 November 2010 Open Access

Scattering attenuation microscopy of oral epithelial dysplasia

Peter Tomlins, Oluyori Adegun, Eleni Hagi-Pavli, Kim Piper, Dan Bader, Farida Fortune

JBO, Vol. 15, Issue 06, 066003, (November 2010) https://doi.org/10.1117/12.10.1117/1.3505019

KEYWORDS: Scattering, Optical coherence tomography, Tissues, Signal attenuation, Tissue optics, Biopsy, Microscopy, Light scattering, Natural surfaces, Image segmentation

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Proceedings Article | 25 February 2010 Paper

Understanding the nature of optical coherence tomography images using Monte Carlo modeling

Andrew Beaumont, Michael Hu, Peter Tomlins

Proceedings Volume 7566, 75660K (2010) https://doi.org/10.1117/12.841893

KEYWORDS: Optical coherence tomography, Scattering, Anisotropy, Refractive index, Tissue optics, Monte Carlo methods, Tissues, Optical properties, Light scattering, Computer simulations

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Proceedings Article | 11 February 2010 Paper

Contrast phantoms for optical coherence tomography

Peter Woolliams, Peter Tomlins

Proceedings Volume 7567, 756704 (2010) https://doi.org/10.1117/12.841863

KEYWORDS: Optical coherence tomography, Scattering, Modulation transfer functions, Contrast transfer function, Spatial frequencies, Modulation, Point spread functions, Optical transfer functions, Light scattering, Optical testing

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Proceedings Article | 20 February 2009 Paper

Refractive index mapping of layered samples using optical coherence refractometry

Matthew Tedaldi, Peter Woolliams, Christian Hart, Andrew Beaumont, Pete Tomlins

Proceedings Volume 7171, 71710V (2009) https://doi.org/10.1117/12.809090

KEYWORDS: Refractive index, Optical coherence tomography, Refractometry, Geometrical optics, Radon transform, Silica, Coherence (optics), Interfaces, Interferometry, Laser beam diagnostics

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Proceedings Article | 18 February 2008 Paper

Measurement of the three-dimensional point-spread function in an optical coherence tomography imaging system

Peter Tomlins, Peter Woolliams, Matthew Tedaldi, Andrew Beaumont, Christian Hart

Proceedings Volume 6847, 68472Q (2008) https://doi.org/10.1117/12.766576

KEYWORDS: Optical coherence tomography, Particles, Point spread functions, 3D acquisition, 3D image processing, Optical spheres, Imaging systems, Image resolution, Calibration, Spectral resolution

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Proceedings Article | 11 February 2008 Paper

Dynamic cure measurement of dental polymer composites using optical coherence tomography

Peter Tomlins, Will Palin, Adrian Shortall

Proceedings Volume 6843, 68430D (2008) https://doi.org/10.1117/12.763305

KEYWORDS: Optical coherence tomography, Refractive index, Composites, Polymers, Lamps, Geometrical optics, Composite resins, Spectroscopy, Glasses, Interferometers

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Proceedings Article | 6 February 2008 Paper

Complex flow characterisation of a porous tissue scaffold measured by Doppler optical coherence tomography

Peter Tomlins, Yiwei Wang, Bufa Zhang, Matthew Tedaldi, Paul Tomlins

Proceedings Volume 6858, 685804 (2008) https://doi.org/10.1117/12.761772

KEYWORDS: Optical coherence tomography, Tissues, Tissue optics, Fluid dynamics, Doppler tomography, CCD cameras, Optical testing, Doppler effect, Spectroscopy, Tissue engineering

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Proceedings Article | 11 July 2007 Paper

Stereoscopic optical coherence tomography in the frequency domain for refractive index sensitive imaging

Peter Tomlins, Matthew Tedaldi, Robert Ferguson, Ruikang Wang

Proceedings Volume 6627, 66270O (2007) https://doi.org/10.1117/12.728040

KEYWORDS: Refractive index, Optical coherence tomography, Interfaces, Composites, In vivo imaging, Ocean optics, Silica, Optical testing, Tissue optics, Signal detection

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SPIE Journal Paper | 1 January 2007 Open Access

Time-resolved simultaneous measurement of group index and physical thickness during photopolymerization of resin-based dental composite

Peter Tomlins, Will Palin, Adrian Shortall, Ruikang Wang

JBO, Vol. 12, Issue 01, 014020, (January 2007) https://doi.org/10.1117/12.10.1117/1.2709877

KEYWORDS: Refractive index, Composites, Polymerization, Composite resins, Polymers, Fourier transforms, Lamps, Interferometry, Photorefractive polymers, Particles

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Proceedings Article | 20 February 2006 Paper

High-speed frequency-swept light source at 1550 nm for Fourier domain OCT with A-scanning rate at 20 kHz

R. Wang, S. Cheung, P. Tomlins, C. Chong, A. Morosawa, D. Heard

Proceedings Volume 6079, 607917 (2006) https://doi.org/10.1117/12.648726

KEYWORDS: Optical coherence tomography, Light sources, Imaging systems, Mirrors, Ranging, Laser sources, Semiconductor optical amplifiers, Diffraction gratings, Tissue optics, Glasses

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Proceedings Article | 20 February 2006 Paper

Layer dependent refractive index measurement by Fourier domain optical coherence tomography

Peter Tomlins, Ruikang Wang

Proceedings Volume 6079, 607913 (2006) https://doi.org/10.1117/12.645719

KEYWORDS: Refractive index, Optical coherence tomography, Data modeling, Scattering, Silica, Interfaces, Statistical modeling, Composites, Calibration, Biomedical optics

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Showing 5 of 18 publications

Conference Committee Involvement (4)

Dynamics and Fluctuations in Biomedical Photonics XVII

1 February 2020 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XVI

2 February 2019 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XV

28 January 2018 | San Francisco, California, United States

Optics in Tissue Engineering and Regenerative Medicine III

24 January 2009 | San Jose, California, United States

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