Dr. Pradeep K. Gupta Profile

Dr. Pradeep K. Gupta

at Raja Ramanna Ctr for Advanced Technology

SPIE Involvement:

Author

Publications (22)

Proceedings Article | 15 June 2015 Paper

Controlled shaping of photonic nanojets using core shell microspheres

P. Kushwaha, H. Patel, M. Swami, P. Gupta

Proceedings Volume 9654, 96541H (2015) https://doi.org/10.1117/12.2182806

KEYWORDS: Refractive index, Photonic nanostructures, Imaging spectroscopy, Numerical simulations, Dielectrics, Nanoimaging, Lithography, Diffraction, Light wave propagation, Raman spectroscopy

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SPIE Journal Paper | 14 August 2014 Open Access

Polarized Raman spectroscopic investigations on hemoglobin ordering in red blood cells

Sunita Ahlawat, Aniket Chowdhury, Nitin Kumar, Abha Uppal, Ravi Shanker Verma, Pradeep Kumar Gupta

JBO, Vol. 19, Issue 08, 087002, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.087002

KEYWORDS: Raman spectroscopy, Polarization, Molecules, Spectroscopy, Blood, Light scattering, Oxygen, Optical tweezers, Proteins, Spatial light modulators

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SPIE Journal Paper | 28 April 2014

White light diffraction phase microscopy as profilometry tool

Sanjit Debnath, Yogesh Verma, Pradeep Gupta

OE, Vol. 53, Issue 09, 092008, (April 2014) https://doi.org/10.1117/12.10.1117/1.OE.53.9.092008

KEYWORDS: Diffraction, Microscopy, CCD cameras, Profiling, Diffraction gratings, Interferometers, Cameras, Reflection, Fourier transforms, Microscopes

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SPIE Journal Paper | 1 July 2011 Open Access

Studies on erythrocytes in malaria infected blood sample with Raman optical tweezers

Raktim Dasgupta, Ravi Verma, Sunita Ahlawat, Abha Uppal, Pradeep Gupta

JBO, Vol. 16, Issue 07, 077009, (July 2011) https://doi.org/10.1117/12.10.1117/1.3600011

KEYWORDS: Raman spectroscopy, Blood, Optical tweezers, Signal to noise ratio, Oxygen, Spectroscopy, Glasses, Linear filtering, CCD cameras, Biomedical optics

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SPIE Journal Paper | 1 November 2010 Open Access

Optical trapping of spermatozoa using Laguerre-Gaussian laser modes

Raktim Dasgupta, Sunita Ahlawat, Ravi Verma, Sunita Shukla, Pradeep Gupta

JBO, Vol. 15, Issue 06, 065010, (November 2010) https://doi.org/10.1117/12.10.1117/1.3526362

KEYWORDS: Continuous wave operation, Transmission electron microscopy, Absorption, Optical tweezers, Luminescence, Modes of laser operation, Adaptive optics, Spatial light modulators, Laser applications, Objectives

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SPIE Journal Paper | 1 September 2010 Open Access

Hemoglobin degradation in human erythrocytes with long-duration near-infrared laser exposure in Raman optical tweezers

Raktim Dasgupta, Sunita Ahlawat, Ravi Verma, Abha Uppal, Pradeep Gupta

JBO, Vol. 15, Issue 05, 055009, (September 2010) https://doi.org/10.1117/12.10.1117/1.3497048

KEYWORDS: Raman spectroscopy, Optical tweezers, Blood, Absorption, Near infrared, Proteins, Iron, Laser applications, Linear filtering, Spectroscopy

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SPIE Journal Paper | 1 August 2008

Surface-plasmon-resonance enhancement: effects on optical trapping and manipulation of nano-objects

Samarendra Mohanty, Kompalli Rao, Pradeep Gupta

JNP, Vol. 2, Issue 01, 023509, (August 2008) https://doi.org/10.1117/12.10.1117/1.2976418

KEYWORDS: Nanoparticles, Absorption, Particles, Molecules, Optical tweezers, Gold, Resonance enhancement, Dielectrics, Luminescence, Objectives

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SPIE Journal Paper | 1 February 2008

Effect of oil vapor contamination on the performance of porous silica sol-gel antireflection-coated optics in vacuum spatial filters of high-power neodymium glass laser

R. Pareek, M. Kumbhare, C. Mukherjee, A. Joshi, Pradeep Gupta

OE, Vol. 47, Issue 02, 023801, (February 2008) https://doi.org/10.1117/12.10.1117/1.2844551

KEYWORDS: Optical coatings, Silica, Reflectivity, Head-mounted displays, Antireflective coatings, Refractive index, Contamination, High power lasers, Sol-gels, Spatial filters

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Proceedings Article | 26 April 2007 Paper

Optical trapping near a charged surface: three-dimensional optical binding of colloids

S. Ahlawat, R. Dasgupta, P. Gupta

Proceedings Volume 6535, 65350W (2007) https://doi.org/10.1117/12.740964

KEYWORDS: Particles, Glasses, Optical binding, Optical tweezers, Objectives, Picosecond phenomena, Charged particle optics, Optical filters, Liquids, YAG lasers

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Proceedings Article | 26 April 2007 Paper

Quantitative tissue polarimetry using polar decomposition of 3 x 3 Mueller matrix

M. Swami, S. Manhas, P. Buddhiwant, N. Ghosh, A. Uppal, P. Gupta

Proceedings Volume 6535, 65350J (2007) https://doi.org/10.1117/12.740806

KEYWORDS: Polarization, Tissues, Scattering, Light scattering, Wave plates, Polarimetry, Tissue optics, Diagnostics, Collagen, Linear polarizers

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Proceedings Article | 8 March 2007 Paper

Laser scanning confocal microscopy and laser tweezers based experiments to understand dentine-bacteria interactions

Sum Chee Peng, Samarendra Mohanty, P. Gupta, Anil Kishen

Proceedings Volume 6425, 642504 (2007) https://doi.org/10.1117/12.701784

KEYWORDS: Collagen, Calcium, Bacteria, Optical tweezers, Confocal microscopy, Objectives, Laser scanners, Optical filters, Charge-coupled devices, Microscopes

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Proceedings Article | 19 February 2007 Paper

Aberrated optical tweezers for manipulation of microscopic objects

Samarendra Mohanty, Pradeep Gupta

Proceedings Volume 6441, 64411O (2007) https://doi.org/10.1117/12.705749

KEYWORDS: Particles, Optical tweezers, Microfluidics, Nanoparticles, Refractive index, Silica, Microscopes, Objectives, Blood, Beam splitters

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Proceedings Article | 7 February 2007 Paper

Tapered single mode fiber tip for high lateral resolution imaging in optical coherence tomography

Y. Verma, K. Divakar Rao, S. Mohanty, P. Gupta

Proceedings Volume 6436, 64360Y (2007) https://doi.org/10.1117/12.716865

KEYWORDS: Optical coherence tomography, Image resolution, Single mode fibers, Objectives, Coherence imaging, Etching, Distance measurement, Optical resolution, Resolution enhancement technologies, Signal to noise ratio

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Proceedings Article | 11 September 2006 Paper

RBCs under optical tweezers as cellular motors and rockers: microfluidic applications

Samarendra Mohanty, Khyati Mohanty, Pradeep Gupta

Proceedings Volume 6326, 63262E (2006) https://doi.org/10.1117/12.682001

KEYWORDS: Polarization, Optical tweezers, Microfluidics, Optical alignment, Microfluidic imaging, Blood, Objectives, Optical trapping, YAG lasers, Wave plates

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Proceedings Article | 21 July 2006 Paper

Monitoring of UVA-induced apoptosis in MCF-7 cells by light-scattering measurements

N. Ghosh, A. Uppal, S. Majumder, P. Gupta

Proceedings Volume 6163, 616314 (2006) https://doi.org/10.1117/12.697317

KEYWORDS: Light scattering, Scattering, Cell death, Transmittance, Mie scattering, Diffuse reflectance spectroscopy, Anisotropy, Integrating spheres, Collimation, Optical testing

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Proceedings Article | 21 July 2006 Paper

Muller matrix approach for determination of optical rotation in chiral turbid media in backscattering geometry

S. Manhas, M. Swami, P. Buddhiwant, N. Ghosh, P. Gupta, K. Singh

Proceedings Volume 6163, 61630W (2006) https://doi.org/10.1117/12.697294

KEYWORDS: Backscatter, Polarization, Scattering, Glucose, Light scattering, Wave plates, Tissue optics, Molecules, Mie scattering, Spherical lenses

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SPIE Journal Paper | 1 March 2005 Open Access

Support vector machine for optical diagnosis of cancer

S. Majumder, Nirmalya Ghosh, Pradeep Gupta

JBO, Vol. 10, Issue 02, 024034, (March 2005) https://doi.org/10.1117/12.10.1117/1.1897396

KEYWORDS: Diagnostics, Algorithm development, Tissues, Ferroelectric LCDs, Cancer, Principal component analysis, Laser induced fluorescence, Feature extraction, Tissue optics, Binary data

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Proceedings Article | 12 September 2002 Paper

Depolarization of light in turbid medium: effect of collection geometry

Nirmalya Ghosh, Pradeep Gupta, Hari Patel, Beena Jain, Bhrigu Singh

Proceedings Volume 4916, (2002) https://doi.org/10.1117/12.482942

KEYWORDS: Tissues, Light scattering, Scattering, Polarization, Tissue optics, Photons, Monte Carlo methods, Geometrical optics, Anisotropy, Laser scattering

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Proceedings Article | 12 September 2002 Paper

Polarization-gated optical imaging: effect of size parameter of scatterer

Nirmalya Ghosh, Pradeep Gupta, Hari Patel, Bhrigu Singh

Proceedings Volume 4916, (2002) https://doi.org/10.1117/12.482955

KEYWORDS: Polarization, Light scattering, Scattering, Refractive index, Mie scattering, Optical imaging, Electromagnetic theory, Water, Biomedical optics, Spherical lenses

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Proceedings Article | 26 October 2001 Paper

In-vivo pharmacokinetics of delta-ALA induced PPIX during photodynamic therapy on mice tumor model

Diagaradjane Parmeswearan, Prakasa Aruna, Pradeep Gupta, Singaravelu Ganesan

Proceedings Volume 4433, (2001) https://doi.org/10.1117/12.446514

KEYWORDS: Photodynamic therapy, Tumors, Tissues, Luminescence, Mathematical modeling, In vivo imaging, Diffusion, Data modeling, Laser therapeutics, Cancer

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In the recent years (delta) -aminolevulinic acid ((delta) -ALA) a precursor for the endogenous production of protoporphyrin IX (PPIX) has gained importance in the Photodynamic Therapy (PDT) of superficial and early-stage cancers. Though (delta) -ALA is present naturally in the cells, systemic administration of exogenous (delta) -ALA leads to the production of intracellular endogenous PP IX in both the tumor and the normal cells, but with varying concentration. However, the PPIX is accumulated more in the tumor tissues as the fast growing tumor cells take up the administered (delta) -ALA more than the normal cells. As the therapeutic efficacy of PDT is dependent on the post (delta) -ALA incubation time, at which the tumor to normal ratio of the PPIX concentration is high, the concentration of the PPIX in the normal and the tumor site were estimated using fluorescence spectroscopy. However, the estimation of the PPIX concentration during/after PDT is mandatory, as the PDT dosimetry is dependent on the sensitizer concentration at the target of interest. The observed variation in the concentration of PPIX in the tumor site with respect to the unexposed normal surrounding tissues, may be attributed to the diffusion of PPIX from the surrounding normal tissues to the tumor site, across the concentration gradient. Based on this a mathematical model has been proposed, to estimate the rate parameter for the diffusion of PPIX from the surrounding normal tissues in to the tumor tissue (K_m), due to photobleaching during PDT at two different fluence. The K_m value at two different fluences, 57.6 and 36 J/cm2 are estimated as 5.444+/- 1.186 and 3.221+/- 0.957, respectively. Further, the rate parameter for the cleavage and efflux of (delta) -ALA (K₁), and the rate parameter for the evasion of the PPIX from the tumor tissues during PDT (K_t), were also estimated by fitting the experimental data to the developed mathematical model. The estimated parameters will be utilized to estimate the exact concentration of PPIX in the tumor tissues for a better PDT efficacy.

Proceedings Article | 19 August 1994 Paper

High-resolution spectroscopy of the OCD-bending mode of methanol-D1 and assignments of far-infrared laser lines

I. Mukhopadhyay, Pradeep Gupta

Proceedings Volume 2211, (1994) https://doi.org/10.1117/12.183015

KEYWORDS: Far infrared lasers, Absorption, Carbon dioxide lasers, Spectroscopy, Laser optics, Molecules, Carbon dioxide, Polarization, Far infrared, Medium wave

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Proceedings Article | 19 August 1994 Paper

Assignments and predictions of optically pumped far-infrared laser lines in C-13 methanol

I. Mukhopadhyay, Pradeep Gupta

Proceedings Volume 2211, (1994) https://doi.org/10.1117/12.183014

KEYWORDS: Far infrared lasers, Carbon dioxide lasers, Spectroscopy, Absorption, Infrared radiation, Carbon dioxide, Infrared spectroscopy, Laser optics, Far infrared, Polarization

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Showing 5 of 22 publications

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