Prof. Rebecca Re Profile

Prof. Rebecca Re

at Politecnico di Milano

SPIE Involvement:

Author

Publications (28)

Proceedings Article | 9 August 2023 Paper

Cerebral resting state oscillations study with TD fNIRS

R. Re, L. Contini, D. Contini, F. Orihuela-Espina, A. Torricelli, L. Spinelli

Proceedings Volume 12628, 126280I (2023) https://doi.org/10.1117/12.2668895

KEYWORDS: Temperature metrology, Spectral density, Skin, Sampling rates, Pulse signals, Numerical simulations, Near infrared spectroscopy, In vivo imaging, Hemodynamics, Brain

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Proceedings Article | 9 August 2023 Paper

Evaluation of muscle aging with TD NIRS and DCS

M. Nabacino, C. Amendola, D. Contini, L. Spinelli, A. Torricelli, A. Pilotto, M. Ansaldo, S. Porcelli, F. Lauretani, A. Hoxha, M. Maggio, R. Re

Proceedings Volume 12628, 126282E (2023) https://doi.org/10.1117/12.2670876

KEYWORDS: Muscles, Near infrared spectroscopy, Hemodynamics, Blood circulation, Oxygen, Tissues, Spectroscopy, Medicine, Electromyography

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Proceedings Article | 9 August 2023 Paper

Assessing TD fNIRS capability to detect hemodynamic oscillations in cerebral cortex

L. Contini, R. Re, D. Contini, A. Torricelli, L. Spinelli

Proceedings Volume 12628, 126280H (2023) https://doi.org/10.1117/12.2670919

KEYWORDS: Hemodynamics, Cerebral cortex, Tissues, Signal detection, Near infrared spectroscopy, In vivo imaging, Feature extraction, Diffusion

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SPIE Journal Paper | 17 July 2023 Open Access

Robustness of tissue oxygenation estimates by continuous wave space-resolved near infrared spectroscopy

Caterina Amendola, Davide Contini, Rebecca Re, Lorenzo Spinelli, Lorenzo Frabasile, Pietro Levoni, Alessandro Torricelli

JBO, Vol. 28, Issue 07, 075002, (July 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.7.075002

KEYWORDS: Tissues, Hemodynamics, Scattering, Near infrared spectroscopy, Oxygenation, Error analysis, Simulations, Muscles, Adaptive optics, Oxygen

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SignificanceContinuous wave near infrared spectroscopy (CW-NIRS) is widely exploited in clinics to estimate skeletal muscles and brain cortex oxygenation. Spatially resolved spectroscopy (SRS) is generally implemented in commercial devices. However, SRS suffers from two main limitations: the a priori assumption on the spectral dependence of the reduced scattering coefficient [μs′(λ)] and the modeling of tissue as homogeneous.AimWe studied the accuracy and robustness of SRS NIRS. We investigated the errors in retrieving hemodynamic parameters, in particular tissue oxygen saturation (StO2), when μs′(λ) was varied from expected values, and when layered tissue was considered.ApproachWe simulated hemodynamic variations mimicking real-life scenarios for skeletal muscles. Simulations were performed by exploiting the analytical solutions of the photon diffusion equation in different geometries: (1) semi-infinite homogeneous medium and constant μs′(λ); (2) semi-infinite homogeneous medium and linear changes in μs′(λ); (3) two-layered media with a superficial thickness s1 = 5, 7.5, 10 mm and constant μs′(λ). All simulated data were obtained at source-detector distances ρ = 35, 40, 45 mm, and analyzed with the SRS approach to derive hemodynamic parameters (concentration of oxygenated and deoxygenated hemoglobin, total hemoglobin concentration, and tissue oxygen saturation, StO2) and their relative error.ResultsVariations in μs′(λ) affect the estimated StO2 (up to ±10 % ), especially if changes are different at the two wavelengths. However, the main limitation of the SRS method is the presence of a superficial layer: errors strongly larger than 20% were retrieved for the estimated StO2 when the superficial thickness exceeds 5 mm.ConclusionsThese results highlight the need for more sophisticated strategies (e.g., the use of multiple short and long distances) to reduce the influence of superficial tissues in retrieving hemodynamic parameters and warn the SRS users to be aware of the intrinsic limitation of this approach, particularly when exploited in the clinical environment.

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SPIE Journal Paper | 15 June 2022 Open Access

Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Michał Kacprzak, Piotr Sawosz, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu-Venkata-Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Lorenzo Frabasile, Pietro Levoni, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alberto Tosi, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

JBO, Vol. 27, Issue 07, 074716, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074716

KEYWORDS: Raster graphics, Optical properties, Diffuse optical imaging, Scattering, Imaging spectroscopy, Absorption, Tissue optics, Spectroscopes, Sensors, Oximetry

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Proceedings Article | 9 December 2021 Paper

Brain activations during programming tasks: TD-NIRS and EEG study

Caterina Amendola, Alessandra Calcagno, Rebecca Re, Ileana Pirovano, Davide Contini, Lorenzo Spinelli, Ricardo Couceiro, João Durães, Raul Barbosa, Paulo de Carvalho, Henrique Madeira, Anna Maria Bianchi, Alessandro Torricelli

Proceedings Volume 11920, 119200K (2021) https://doi.org/10.1117/12.2615229

KEYWORDS: Electroencephalography, Computer programming, Hemodynamics, Brain activation, Sensors, Near infrared spectroscopy, Brain, Statistical analysis, Computer programming languages, Visualization

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Proceedings Article | 9 December 2021 Paper

Adipose tissue thickness and optical properties affect differential pathlength factor in NIRS studies on human skeletal muscle

Ileana Pirovano, Simone Porcelli, Rebecca Re, Lorenzo Spinelli, Davide Contini, Mauro Marzorati, Alessandro Torricelli

Proceedings Volume 11920, 119200T (2021) https://doi.org/10.1117/12.2615254

KEYWORDS: Near infrared spectroscopy, Tissue optics, Optical properties, In vivo imaging, Scattering, Tissues, Absorption, Photons, Time metrology, Spectroscopy

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Proceedings Article | 9 December 2021 Paper

Filament 3D printing technology for diffuse optics applications: advantages and drawbacks

Caterina Amendola, Michele Lacerenza, Ileana Pirovano, Davide Contini, Lorenzo Spinelli, Rinaldo Cubeddu, Alessandro Torricelli, Rebecca Re

Proceedings Volume 11920, 1192020 (2021) https://doi.org/10.1117/12.2615431

KEYWORDS: 3D printing, Mass attenuation coefficient, Printing, 3D metrology, Near infrared spectroscopy, Diffuse optical imaging, 3D acquisition, Spectroscopy, Photons, Optical properties

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Proceedings Article | 9 December 2021 Paper

Discrimination between healthy and glaucomatous subjects with TD-fNIRS

R. Re, D. Messenio, G. Marano, L. Spinelli, I. Pirovano, D. Contini, R. Colombo, P. Boracchi, E. Biganzoli, R. Cubeddu, A. Torricelli

Proceedings Volume 11920, 119200G (2021) https://doi.org/10.1117/12.2615222

KEYWORDS: Visualization, Eye, Statistical analysis, Brain, Hemodynamics, Eye models, Absorption, Visual optics, Scattering, Medical devices

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Proceedings Article | 7 December 2021 Paper

Rehabilitation monitoring after bed rest in elderly: TD-NIRS and sEMG preliminary study

I. Pirovano, A. Laurini, A. Tomba, A. Scano, R. Re, A. Caserta, L. Spinelli, D. Contini, R. Cubeddu, L. Panella, A. Torricelli

Proceedings Volume 11919, 1191921 (2021) https://doi.org/10.1117/12.2615017

KEYWORDS: Tissues, Electromyography, Hemodynamics, Near infrared spectroscopy, Ultrasonography, Surgery, Scattering, Oxygen, Head, Data analysis

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Proceedings Article | 7 December 2021 Paper

Assessment of muscular sustained fatigue: a TD-NIRS and sEMG study

R. Re, A. Scano, I. Pirovano, M. Manunza, L. Spinelli, D. Contini, A. Torricelli

Proceedings Volume 11919, 119191H (2021) https://doi.org/10.1117/12.2614859

KEYWORDS: Near infrared spectroscopy, Signal detection, Mode conditioning cables, Tissue optics, Reflectivity, Physics, Oxygen, Optical testing, Motion analysis, Medical device development

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Proceedings Article | 5 March 2021 Presentation + Paper

A multi-laboratory comparison of photon migration instruments and their performances: the BitMap exercise

Sri Rama Pranav Kumar Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Giuseppe Lo Presti, Lorenzo Cortese, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Piotr Sawosz, Michal Kacprzak, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu Venkata Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Alessandro Torricelli, Alberto Tosi, Paola Taroni, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11639, 116390F (2021) https://doi.org/10.1117/12.2578521

KEYWORDS: Raster graphics, Photonic devices, Tissue optics, Spectroscopes, Oximetry, Optical components, Mammography, Imaging spectroscopy, Functional imaging

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Proceedings Article | 11 July 2019 Paper

Preliminary vastus lateralis characterization with time domain near infrared spectroscopy during incremental cycle exercise

I. Pirovano, S. Porcelli, F. Azzarello, R. Re, L. Spinelli, D. Contini, M. Marzorati, A. Torricelli

Proceedings Volume 11074, 1107424 (2019) https://doi.org/10.1117/12.2527068

KEYWORDS: Near infrared spectroscopy, Blood, Absorption, Scattering, Tissues, Optical properties, Hemodynamics, Signal processing, Functional near infrared spectroscopy

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Proceedings Article | 11 July 2019 Paper

Instrument response function acquisition in reflectance geometry for time-resolved diffuse optical measurements

Ileana Pirovano, Rebecca Re, Davide Contini, Lorenzo Spinelli, Alessandro Torricelli

Proceedings Volume 11074, 110742R (2019) https://doi.org/10.1117/12.2526931

KEYWORDS: Reflectivity, Optical fibers, Tissues, Photons, Optical testing, 3D acquisition, Scattering, In vivo imaging, 3D metrology, Data modeling

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Proceedings Article | 11 July 2019 Paper

TD-fNIRS for diagnosing glaucoma: a clinical pilot study

R. Re, D. Messenio, L. Spinelli, I. Pirovano, D. Contini, R. Colombo, R. Cubeddu, A. Torricelli

Proceedings Volume 11074, 110741K (2019) https://doi.org/10.1117/12.2526961

KEYWORDS: Visualization, Visual cortex, Hemodynamics, Signal detection, Eye, Optic nerve, Brain, Optical coherence tomography, Visual optics, Optical discs

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Proceedings Article | 11 July 2019 Paper

Time-resolved near infrared spectroscopy in ischemic stroke patients

Marta Zanoletti, Giacomo Giacalone, Davide Contini, Rebecca Re, Lorenzo Spinelli, Bruno Germinario, Luisa Roveri, Alessandro Torricelli

Proceedings Volume 11074, 110740T (2019) https://doi.org/10.1117/12.2530627

KEYWORDS: Ischemic stroke, Near infrared spectroscopy, Absorption, Scattering, Tissues, Control systems, Brain, Photons, Reflectivity, Mie scattering

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SPIE Journal Paper | 7 February 2019 Open Access

Time-domain near-infrared spectroscopy in acute ischemic stroke patients

Giacomo Giacalone, Marta Zanoletti, Rebecca Re, Bruno Germinario, Davide Contini, Lorenzo Spinelli, Alessandro Torricelli, Luisa Roveri

NPh, Vol. 6, Issue 01, 015003, (February 2019) https://doi.org/10.1117/12.10.1117/1.NPh.6.1.015003

KEYWORDS: Control systems, Ischemic stroke, Near infrared spectroscopy, Brain, Tissues, Oxygen, Neuroimaging, Tissue optics, Neurophotonics, Photons

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SPIE Journal Paper | 12 October 2016 Open Access

Probe-hosted silicon photomultipliers for time-domain functional near-infrared spectroscopy: phantom and in vivo tests

Rebecca Re, Edoardo Martinenghi, Alberto Dalla Mora, Davide Contini, Antonio Pifferi, Alessandro Torricelli

NPh, Vol. 3, Issue 04, 045004, (October 2016) https://doi.org/10.1117/12.10.1117/1.NPh.3.4.045004

KEYWORDS: Sensors, Optical fibers, Silicon photomultipliers, In vivo imaging, Absorption, Hemodynamics, Brain, Near infrared spectroscopy, Signal detection, Electroencephalography

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SPIE Journal Paper | 28 July 2015 Open Access

Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy

Antonio Pifferi, Alessandro Torricelli, Rinaldo Cubeddu, Giovanna Quarto, Rebecca Re, Sanathana K. V. Sekar, Lorenzo Spinelli, Andrea Farina, Fabrizio Martelli, Heidrun Wabnitz

JBO, Vol. 20, Issue 12, 121304, (July 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.121304

KEYWORDS: Absorption, Solids, Picosecond phenomena, Scattering, Transmittance, Imaging spectroscopy, Sensors, Optical fibers, Optical properties, Reflectivity

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Proceedings Article | 16 July 2015 Paper

Validation of time domain near infrared spectroscopy in muscle measurements: effect of a superficial layer

Rebecca Re, Davide Contini, Lucia Zucchelli, Lorenzo Spinelli, Alessandro Torricelli

Proceedings Volume 9538, 95380Y (2015) https://doi.org/10.1117/12.2183767

KEYWORDS: Hemodynamics, Near infrared spectroscopy, Tissue optics, In vivo imaging, Tissues, Computer simulations, Chromophores, Data modeling, Error analysis, Picosecond phenomena

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Proceedings Article | 16 July 2015 Paper

Design and construction of a solid switchable phantom for diffuse optical imaging

Antonio Pifferi, Fabrizio Martelli, Lorenzo Spinelli, Andrea Farina, Rebecca Re, Giovanna Quarto, Sanathana Konugolu Venkata Sekar, Alessandro Torricelli, Rinaldo Cubeddu, Mikhail Mazurenka, Rainer Macdonald, Heidrun Wabnitz

Proceedings Volume 9538, 95380Q (2015) https://doi.org/10.1117/12.2183657

KEYWORDS: Picosecond phenomena, Solids, Diffuse optical imaging, Absorption, Optical fibers, Reflectivity, Transmittance, Scattering, Optical properties, Brain

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Proceedings Article | 6 March 2015 Paper

Solid switchable phantom for diffuse optical imaging

Antonio Pifferi, Alessandro Torricelli, Rinaldo Cubeddu, Giovanna Quarto, Rebecca Re, Sanathana Konugolu Venkata Sekar, Lorenzo Spinelli, Andrea Farina, Fabrizio Martelli, Heidrun Wabnitz

Proceedings Volume 9325, 932505 (2015) https://doi.org/10.1117/12.2084789

KEYWORDS: Absorption, Solids, Transmittance, Scattering, Optical properties, Imaging systems, Picosecond phenomena, Diffuse optical imaging, Optical spheres, Electroluminescent displays

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SPIE Journal Paper | 14 August 2014 Open Access

Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol

Heidrun Wabnitz, Alexander Jelzow, Mikhail Mazurenka, Oliver Steinkellner, Rainer Macdonald, Daniel Milej, Norbert Żołek, Michał Kacprzak, Piotr Sawosz, Roman Maniewski, Adam Liebert, Salavat Magazov, Jeremy Hebden, Fabrizio Martelli, Paola Di Ninni, Giovanni Zaccanti, Alessandro Torricelli, Davide Contini, Rebecca Re, Lucia Zucchelli, Lorenzo Spinelli, Rinaldo Cubeddu, Antonio Pifferi

JBO, Vol. 19, Issue 08, 086012, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.086012

KEYWORDS: Absorption, Brain, Neuroimaging, Imaging systems, Optical properties, Sensors, Data analysis, Liquids, Biomedical optics, Spatial resolution

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Proceedings Article | 24 June 2013 Paper

Multichannel time domain fNIRS mapping of cortical activation and superficial systemic responses during neuromuscular electrical stimulation

R. Re, M. Muthalib, L. Zucchelli, S. Perrey, D. Contini, M. Caffini, L. Spinelli, G. Kerr, A. Torricelli

Proceedings Volume 8804, 880404 (2013) https://doi.org/10.1117/12.2032512

KEYWORDS: Cortical activation, Brain mapping, Photons, Hemodynamics, Scanning probe microscopy, Sensors, Head, Heart, Skin, Tissue optics

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Proceedings Article | 24 June 2013 Paper

A method for discriminating systemic and cortical hemodynamic changes by time domain fNIRS

Lucia Zucchelli, Lorenzo Spinelli, Davide Contini, Rebecca Re, Alessandro Torricelli

Proceedings Volume 8804, 88040B (2013) https://doi.org/10.1117/12.2032503

KEYWORDS: Hemodynamics, Absorption, Head, Near infrared spectroscopy, Tissues, In vivo imaging, Brain, Photodetectors, Scattering, Multilayers

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Proceedings Article | 25 March 2013 Paper

Multi-channel time-resolved functional near infrared spectroscopy system

D. Contini, R. Re, M. Turola, L. Spinelli, G. Romano, R. Cubeddu, A. Torricelli

Proceedings Volume 8578, 857832 (2013) https://doi.org/10.1117/12.2004967

KEYWORDS: Brain, Absorption, Functional near infrared spectroscopy, Hemodynamics, Sensors, Tissues, Tissue optics, In vivo imaging, Signal to noise ratio, Control systems

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Proceedings Article | 25 March 2013 Paper

Investigation of verbal and visual working memory by multi-channel time-resolved functional near-infrared spectroscopy

D. Contini, M. Caffini, R. Re, L. Zucchelli, L. Spinelli, S. Basso Moro, S. Bisconti, M. Ferrari, V. Quaresima, S. Cutini, A. Torricelli

Proceedings Volume 8578, 85782Z (2013) https://doi.org/10.1117/12.2003777

KEYWORDS: Visualization, Near infrared spectroscopy, Prefrontal cortex, Heart, Information operations, Oximeters, Lithium, Hemodynamics, Neuroimaging, Barium

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Proceedings Article | 8 July 2009 Paper

A compact time-resolved system for NIR spectroscopy

Rebecca Re, Davide Contini, Matteo Caffini, Lorenzo Spinelli, Rinaldo Cubeddu, Alessandro Torricelli

Proceedings Volume 7368, 736815 (2009) https://doi.org/10.1117/12.831610

KEYWORDS: Near infrared, Absorption, Near infrared spectroscopy, Spectroscopy, Scattering, Time resolved spectroscopy, Tissue optics, Hemodynamics, Tissues, Neodymium

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Showing 5 of 28 publications

Conference Committee Involvement (1)

Diffuse Optical Spectroscopy and Imaging VIII

20 June 2021 | Online Only, Germany

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