Dr. Sacha Noimark Profile

Dr. Sacha Noimark

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Publications (12)

Proceedings Article | 27 March 2023 Poster

Visualisation of medical needles using photoacoustic imaging with candle soot composites coatings and deep learning

Mengjie Shi, Semyon Bodian, Simeon West, Sanjayan Sathasivam, Ross Gordon, Paul Collier, Tom Vercauteren, Adrien Desjardins, Sacha Noimark, Wenfeng Xia

Proceedings Volume PC12379, PC123792M (2023) https://doi.org/10.1117/12.2648775

KEYWORDS: Visualization, Composites, Photoacoustic imaging, Visibility, Light emitting diodes, Optical fibers, In vivo imaging, Ultrasonography, Tissues, Tissue optics

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Proceedings Article | 20 April 2020 Presentation

High resolution 3D photoacoustic scanner for clinical vascular imaging applications (Conference Presentation)

Nam Trung Huynh, Olivia Francies, Katerina Soteriou, Thomas Allen, Khoa Pham, Sacha Noimark, Semyon bodian, Adrien Desjardins, Jiaqi Zhu, Oshaani Abeyakoon, Filip Kuklis, Edward Zhang, Ben Cox, Andrew Plumb, Paul Beard

Proceedings Volume 11240, 1124003 (2020) https://doi.org/10.1117/12.2549559

KEYWORDS: 3D scanning, Photoacoustic spectroscopy, Laser scanners

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Proceedings Article | 7 March 2019 Presentation

A hybrid approach of two-photon polymerization scaffold printing and microinjection of optically heterogenous material for the fabrication of vascular imaging phantoms (Conference Presentation)

Callum Little, Radhika Poduval, Richard Caulfield, Sacha Noimark, Richard Colchester, Chris Loder, Manish Tiwari, Roby Rakhit, Ioannis Papakonstantinou, Adrien Desjardins

Proceedings Volume 10855, 1085507 (2019) https://doi.org/10.1117/12.2508642

KEYWORDS: Tissue optics, Two photon polymerization, 3D modeling, Printing, Vascular imaging, Tissues, Optical coherence tomography, 3D printing, Imaging systems, Device simulation

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Proceedings Article | 4 March 2019 Presentation

Radio-frequency ablation monitoring through real-time, video-rate all-optical ultrasound imaging (Conference Presentation)

Erwin Alles, Richard Colchester, Sacha Noimark, Edward Zhang, Paul Beard, Malcolm Finlay, Adrien Desjardins

Proceedings Volume 10855, 108550M (2019) https://doi.org/10.1117/12.2507795

KEYWORDS: Ultrasonography, Imaging systems, Radiofrequency ablation, Image resolution, Cardiology, Atrial fibrillation, Tissues, Magnetic resonance imaging, Electronic imaging, Transducers

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Proceedings Article | 4 March 2019 Presentation

Dual mode photoacoustic and ultrasound imaging system based on a Fabry-Perot scanner (Conference Presentation)

Khoa Pham, Sacha Noimark, Nam Trung Huynh, Edward Zhang, Adrien Desjardins, Ben Cox, Paul Beard

Proceedings Volume 10878, 1087826 (2019) https://doi.org/10.1117/12.2506922

KEYWORDS: Scanners, Imaging systems, Photoacoustic spectroscopy, Ultrasonography, Fabry–Perot interferometers, 3D image processing, Tissues, Laser scanners, 3D scanning, In vivo imaging

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Compared to piezoelectric based photoacoustic (PA) scanners, the planar Fabry-Perot (FP) scanner has several advantages. It can provide small element size with high sensitivity, a smooth broadband frequency response, and is transparent to excitation light. This enables the FP scanner to provide excellent high-resolution in vivo PA images of soft tissue to depths up to approximately 10 mm. However, unlike piezoelectric scanners, the FP scanner in its current form cannot provide a pulse-echo ultrasound (US) as well as a PA image, which is useful because of the additional tissue contrast it provides. To address this, a dual mode FP scanner-based system that, for the first time, can acquire co-registered 3D PA and US images has been developed. In order to provide an optical US generation capability, the FP ultrasound sensor was coated with a novel Gold-Nanoparticle-PDMS composite which was excited with nanosecond laser pulses to generate plane wave US pulses. By modifying the FP sensor in this way, it now acts as an US transmitter as well as a receiver. The coating is highly absorbing at the US generation wavelength (>95%) but transparent at the PA excitation wavelength, the latter to allow the system to also operate in PA imaging mode as before. The generated US pulses exhibited peak pressures in the MPa range, which is comparable to the output of conventional piezoelectric based medical US scanners. The pulses had a broad bandwidth (>40 MHz) and the emitted wavefront was planar to within λ/10 at 10 MHz. PA and pulse-echo US signals were mapped in turn by the FP scanner over centimetre scale areas with a step size of 100 μm and an element size of 64 μm. The -3dB bandwidth of the FP sensor was 30 MHz. Reconstruction methods using a k-space formulation recovered co-registered 3D PA and US images. The system’s lateral spatial resolution was evaluated by imaging a line target at depths up to 10 mm and ranged between 50 and 120 μm for both modes. Arbitrarily shaped 3D objects were imaged to demonstrate the volumetric US imaging capability of the scanner. Tissue mimicking phantoms, with impedance mismatches representative of soft tissues, and ex vivo tissue samples were imaged with the system as well as a conventional clinical US scanner for comparison. Finally, the system obtained promising high-resolution 3D dual mode PA-US images for a variety of phantoms with contrast based on both optical absorption and acoustic impedance. This novel all-optical system has the potential to add complementary morphological contrast to photoacoustic vascular images which could aid the clinical assessment of superficial tumours, lymph node disease and other conditions.

Proceedings Article | 27 February 2019 Paper

Enhancing photoacoustic visualization of medical devices with elastomeric nanocomposite coatings

Wenfeng Xia, Sacha Noimark, Efthymios Maneas, Nina Montana Brown, Mithun Kuniyil Ajith Singh, Sebastien Ourselin, Simeon West, Adrien Desjardins

Proceedings Volume 10878, 108783G (2019) https://doi.org/10.1117/12.2508658

KEYWORDS: Photoacoustic imaging, Medical devices, Imaging systems, Visualization, Composites, Ultrasonography, Visibility, Photoacoustic spectroscopy, Tissues, Nanocomposites, Light emitting diodes

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SPIE Journal Paper | 15 February 2019 Open Access

Micron resolution, high-fidelity three-dimensional vascular optical imaging phantoms

Callum D. Little, Radhika K. Poduval, Richard Caulfield, Sacha Noimark, Richard J. Colchester, Chris D. Loder, Manish K. Tiwari, Roby D. Rakhit, Ioannis Papakonstantinou, Adrien E. Desjardins

JBO, Vol. 24, Issue 02, 020502, (February 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.2.020502

KEYWORDS: Tissue optics, Two photon polymerization, 3D modeling, Printing, 3D image processing, Silicon, Tissues, Scattering, Image resolution, Optical imaging

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Proceedings Article | 14 March 2018 Presentation

All-optical side-viewing intravascular ultrasound imaging probe (Conference Presentation)

Richard Colchester, Sacha Noimark, Edward Zhang, Malcolm Finlay, Callum Little, Chris Loder, Roby Rahkit, Ivan Parkin, Paul Beard, Ioannis Papakonstantinou, Adrien Desjardins

Proceedings Volume 10471, 104710V (2018) https://doi.org/10.1117/12.2289848

KEYWORDS: Ultrasonography, Intravascular ultrasound, Transducers, Photoacoustic spectroscopy, Optical fibers, Carbon nanotubes, Laser beam diagnostics, Image resolution, Transmitters, Composites

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Proceedings Article | 14 March 2018 Presentation

Fibre-optic pressure and temperature measurements using phase-resolved low-coherence interferometry (Conference Presentation)

Joanna Coote, Sandy Mosse, Sacha Noimark, Erwin Alles, Callum Little, Chris Loder, Roby Rakhit, Malcolm Finlay, Adrien Desjardins

Proceedings Volume 10488, 104880E (2018) https://doi.org/10.1117/12.2290007

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Proceedings Article | 1 August 2017 Paper

Optical fiber laser ultrasound transmitter with electrospun composite for minimally invasive medical imaging

Radhika Poduval, Sacha Noimark, Richard Colchester, Tom Macdonald, Ivan Parkin, Adrien Desjardins, Ioannis Papakonstantinou

Proceedings Volume 10415, 104150B (2017) https://doi.org/10.1117/12.2286162

KEYWORDS: Fiber optics sensors, Ultrasonography, Medical imaging, Optical fibers, Laser optics, Transmitters, Composites, Carbon nanotubes, Polymers

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Proceedings Article | 19 April 2017 Presentation

Development and characterisation of a brain tumour mimicking protoporphyrin IX fluorescence phantom (Conference Presentation)

Yijing Xie, Cristiana Tisca, William Peveler, Sacha Noimark, Adrien Desjardins, Ivan Parkin, Sebastien Ourselin, Tom Vercauteren

Proceedings Volume 10049, 100490F (2017) https://doi.org/10.1117/12.2252018

KEYWORDS: Neuroimaging, Luminescence, Nanoparticles, Brain, Optical phantoms, Optical components, Optical testing, Tissue optics, Optical properties, Scattering

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Proceedings Article | 27 April 2016 Presentation

All-optical pulse-echo ultrasound probe for intravascular imaging (Conference Presentation)

Richard Colchester, Sacha Noimark, Charles Mosse, Edward Zhang, Paul Beard, Ivan Parkin, Ioannis Papakonstantinou, Adrien Desjardins

Proceedings Volume 9689, 96893I (2016) https://doi.org/10.1117/12.2213757

KEYWORDS: Ultrasonography, Tissues, Intravascular ultrasound, Image resolution, Photoacoustic spectroscopy, Echocardiography, Cardiology, Carbon, Composites, Fabry–Perot interferometers

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Showing 5 of 12 publications

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