Mr. Sam Osseiran Profile

Sam Osseiran

PhD Candidate at Massachusetts General Hospital

SPIE Involvement:

Author

Publications (12)

Proceedings Article | 4 March 2019 Presentation

Presentation

Fluorescence lifetime imaging microscopy along with non-Euclidean phasor analysis for visualization of drug distribution of a topical drug in human facial skin (Conference Presentation)

Sinyoung Jeong, Alexander Fast, Sam Osseiran, Maiko Hermsmeier, Tanvee Sawant, Kin Chan, Conor Evans

Proceedings Volume 10859, 1085908 (2019) https://doi.org/10.1117/12.2510218

KEYWORDS: Skin, Visualization, Fluorescence lifetime imaging, Visual analytics, Microscopy, Luminescence

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Proceedings Article | 14 March 2018 Presentation

Presentation

Fluorescence lifetime imaging microscopy (FLIM) for visualization of targeted drug delivery and local distribution in skin of a single daily dose of topical minocycline gel: an update on translational research from preclinical to clinical (Conference Presentation)

Sinyoung Jeong, Maiko Hermsmeier, Sam Osseiran, Akira Yamamoto, Xin Chen, Usha Nagavarapu, Conor Evans, Kin F. Chan, AnnaMarie Daniels

Proceedings Volume 10467, 104670J (2018) https://doi.org/10.1117/12.2294084

KEYWORDS: Fluorescence lifetime imaging, Microscopy, Luminescence, Skin, Visualization, Translational research, Pharmacology, Toxicology, Nonlinear optics

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Proceedings Article | 14 March 2018 Presentation

Presentation

Phasor fluorescence lifetime microscopy of NADH to analyze metabolic activity of adipocytes (Conference Presentation)

Michael Evers, Nunciada Salma, Sam Osseiran, Malte Casper, Reginald Birngruber, Conor Evans, Dieter Manstein

Proceedings Volume 10498, 1049808 (2018) https://doi.org/10.1117/12.2289294

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Multiphoton microscopy, Microscopy, Mode conditioning cables, Multiphoton fluorescence microscopy, Nondestructive evaluation, Oxygen

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Proceedings Article | 14 March 2018 Presentation

Presentation

A non-Euclidean phasor approach for distinction of fluorescent compounds using two-photon fluorescence lifetime imaging microscopy in ex vivo human skin (Conference Presentation)

Sam Osseiran, Elisabeth Roider, Hequn Wang, Yusuke Suita, Michael Murphy, David Fisher, Conor Evans

Proceedings Volume 10498, 104980U (2018) https://doi.org/10.1117/12.2291211

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Proceedings Article | 14 March 2018 Presentation

Presentation

Characterization of skin structure and chemical content in response to topical intervention using coherent Raman scattering imaging (Conference Presentation)

Sam Osseiran, Sinyoung Jeong, Conor Evans

Proceedings Volume 10475, 104750B (2018) https://doi.org/10.1117/12.2291202

KEYWORDS: Skin, Raman scattering, Coherence imaging, CARS tomography, Dermatology, Interfaces, Microscopy, Proteins

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Proceedings Article | 14 March 2018 Presentation

Presentation

Phasor approach to fluorescence lifetime imaging microscopy for visualization and quantification of drug distribution of a topical minocycline gel in human facial skin (Conference Presentation)

Sinyoung Jeong, Maiko Hermsmeier, Sam Osseiran, Akira Yamamoto, Usha Nagavarapu, Kin Chan, Conor Evans

Proceedings Volume 10475, 104750I (2018) https://doi.org/10.1117/12.2290898

KEYWORDS: Fluorescence lifetime imaging, Visualization, Skin, Microscopy, Tissues, Luminescence, Biological research, Molecules, Image visualization, Visual analytics

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SPIE Journal Paper | 9 December 2017 Open Access

Open Access

Non-Euclidean phasor analysis for quantification of oxidative stress in ex vivo human skin exposed to sun filters using fluorescence lifetime imaging microscopy

Sam Osseiran, Elisabeth Roider, Hequn Wang, Yusuke Suita, Michael Murphy, David Fisher, Conor Evans

JBO, Vol. 22, Issue 12, 125004, (December 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.12.125004

KEYWORDS: Sun, Luminescence, Skin, Image filtering, Fluorescence lifetime imaging, Chemical analysis, Microscopy, Ultraviolet radiation, Optical filters, Image processing

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Proceedings Article | 24 April 2017 Presentation

Presentation

Label-free longitudinal monitoring of melanogenesis in the evolution of melanoma treatment resistance (Conference Presentation)

Sam Osseiran, Hequn Wang, Ken Dutton-Regester, Levi Garraway, Conor Evans

Proceedings Volume 10069, 100690N (2017) https://doi.org/10.1117/12.2253399

KEYWORDS: CARS tomography, Melanoma, Resistance, Microscopy, Skin cancer, Skin, Therapeutics, Clinical trials, In vitro testing, Optical microscopy

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Proceedings Article | 19 April 2017 Presentation

Presentation

Noninvasive label-free monitoring of cosmetics and pharmaceuticals in human skin using nonlinear optical microscopy (Conference Presentation)

Sam Osseiran, Hequn Wang, Conor Evans

Proceedings Volume 10046, 1004605 (2017) https://doi.org/10.1117/12.2253390

KEYWORDS: Harmonic generation, Second-harmonic generation, Skin, Microscopy, Tissue optics, Transient nonlinear optics, Optical microscopy, Fluorescence lifetime imaging, Chemical compounds, Luminescence

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Proceedings Article | 27 April 2016 Presentation

Presentation

Towards label-free evaluation of oxidative stress in human skin exposed to sun filters (Conference Presentation)

Sam Osseiran, Hequn Wang, Yusuke Suita, Elisabeth Roider, David Fisher, Conor Evans

Proceedings Volume 9689, 968906 (2016) https://doi.org/10.1117/12.2213406

KEYWORDS: Skin, Sun, Skin cancer, Ultraviolet radiation, Optical filters, Radiation effects, Luminescence, Fluorescence lifetime imaging, Melanoma, Cancer

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Proceedings Article | 27 April 2016 Presentation

Presentation

New imaging-based biomarkers for melanoma diagnosis using coherent Raman Scattering microscopy (Conference Presentation)

Hequn Wang, Sam Osseiran, Elisabeth Roider, David Fisher, Conor Evans

Proceedings Volume 9689, 968904 (2016) https://doi.org/10.1117/12.2213360

KEYWORDS: Melanoma, Microscopy, Skin, Raman scattering, Ultraviolet radiation, CARS tomography, In vivo imaging, Ear, Tissues, Photomedicine

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Proceedings Article | 14 March 2016 Paper

Paper

The nature of multiphoton fluorescence from red blood cells

Ilyas Saytashev, Michael Murphy, Sam Osseiran, Dana Spence, Conor Evans, Marcos Dantus

Proceedings Volume 9712, 97121W (2016) https://doi.org/10.1117/12.2213422

KEYWORDS: Luminescence, Blood, Microscopy, Signal detection, Multiphoton fluorescence microscopy, Single photon, Optical microscopy, Sapphire lasers, Biomedical optics, Mirrors

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Showing 5 of 12 publications

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