Sameer Antani is a Staff Scientist and (Acting) Chief of the Communications Engineering Branch and the Computer Science Branch, respectively, at the Lister Hill National Center for Biomedical Communications, an intramural R&D division of the National Library of Medicine (NLM) part of the National Institutes of Health (NIH) in Bethesda, Maryland, USA. He leads abnd directs R&D in advancing the role of computational sciences and engineering in biomedical research, education, and clinical care. His research applies and studies methods for explaining the behavior of machine intelligence methods in automated decision support in biomedical applications. His expertise includes biomedical imaging, machine learning, medical informatics, information retrieval, computer vision, and related topics in computer science and engineering technology. His contributions include automated screening for high burden diseases such as (i) Tuberculosis (TB) in HIV positive patients using digital chest X-ray image analysis; (ii) cervical cancer in women using analysis of acetowhitened images of the cervix, and whole slide images of liquid-based Pap smears and histopathology images from cervical biopsies; and, (iii) automated methods for detecting malaria parasites in microscopic images of thick and thin blood smears. Other contributions include functional MRI (fMRI) simulation for brain research and similarity retrieval; analysis of ophthalmic fundus images for glaucoma, and, the OPEN-i® biomedical image retrieval system Dr. Antani is a senior member of the SPIE, and IEEE. He serves as the vice chair for computational medicine on the IEEE Computer Society’s Technical Committee on Computational Life Sciences (TCCLS) and the IEEE Life Sciences Technical Community. He is currently on the Editorial Board of MDPI Journal Data.