We propose a generalized, modular, closed-loop system for objective assessment of human visual parameters. Our system presents periodical visual stimuli to the patient's field of view and analyses the consequent evoked brain potentials elicited in the occipital lobe and recorded through EEG. The analysis of the monitored EEG data is performed in an end-to-end fashion by a convolutional neural network (CNN). We propose a novel CNN architecture for EEG signal analysis that can be trained utilizing the benefits of multi-task learning. The closedloop attribute of our system allows for a real-time adaptation of the subsequent stimuli to further examine a potentially damaged area or increase the granularity of the exploration. Interchangeability is provided in terms of software modules, stimulus type, visual hardware, EEG acquisition device and EEG electrodes. Initially, the system is designed to monitor visual field loss originating from glaucoma or damage to the optic nerve using a virtual reality (VR) headset for the stimuli presentation. The modular architecture of our system paves the way for the assessment and monitoring of other neuro-visual functions.
For long, the VR optics designer has been taking advantage of the fact that the eye is not optically perfect and striving towards creating “perfectly imperfect” VR optics. These cheaper and lighter lens systems could have high off-axis aberration, but with negligible impact on visual quality. A good way to test and validate these designs could be simulating the rendered image of the pixel array on the retina. Earlier attempts used the principle of virtual ray tracing, which is inherently a Monte Carlo method and therefore subjects to noise at sharp transition edges. Furthermore, this approach cannot render the Point Spread Function (PSF). We took the reverse approach of physical ray tracing. Rays are generated from each illuminating point and traced forward to the retina. After the tracing process, each light source point generates a number of ray-retina intersections. We propose a novel rasterization algorithm to render the radiometric image on the virtual retina. For the radiometric-correct determination of pixel value, we used the Intersection-over-Area metric. This metric is an indicator for how much the back-projected area of each retinal cell overlaps the triangle formed by the cone of light flux falling on the retina. The geometry of the overlapping was found with the Sutherland-Hodgman algorithm. All images of source points were then superposed to find the resulting image. With the proposed software, it is possible to simulate different VR-optics in combination with eye models. The most significant challenge of the physical ray tracing was the huge calculation workload. Our software overcame this by utilizing parallel GPU computing capability offered by the CUDA platform. For evaluation, we used the software with different schematic models of the eye, including those from Gullstrand, Le Grand, Koojiman and Navarro. We found that the former two, so-called paraxial, eye models predict the eye has higher sagittal resolution than tangential. On the other hand, the latter two (so-called finite eye models) predict the opposite. With this simulation software, optical designers can validate their VR-optics-design and gain more insights about the image formation process. This tool can be used as a virtual optical test bench for the simulation of the imaging result before building a costly prototype.
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