Dr. Steen J. Madsen Profile

Dr. Steen J. Madsen

Professor and Chair at Univ of Nevada Las Vegas

SPIE Involvement:

Editor | Author

Publications (49)

Proceedings Article | 4 March 2019 Presentation

Macrophage-mediated delivery of chemotherapeutics for photochemical internalization (Conference Presentation)

Stephanie Molina, Henry Hirschberg, Steen Madsen

Proceedings Volume 10864, 1086403 (2019) https://doi.org/10.1117/12.2506199

KEYWORDS: Tumors, Radiation effects, Therapeutics, In vitro testing, Toxicity, Biomimetics, Brain, Tissues

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SPIE Journal Paper | 7 February 2018 Open Access

Limiting glioma development by photodynamic therapy-generated macrophage vaccine and allo-stimulation: an in vivo histological study in rats

Steen J. Madsen, Catherine Christie, Khoi Huynh, Qian Peng, Francisco A. Uzal, Tatiana B. Krasieva, Henry Hirschberg

JBO, Vol. 23, Issue 02, 028001, (February 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.2.028001

KEYWORDS: Tumors, Photodynamic therapy, Brain, In vivo imaging, Cell death, Cancer, Flow cytometry, OSLO, Animal model studies, Phase contrast

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Proceedings Article | 19 April 2017 Presentation

Macrophages as drug delivery vehicles for photochemical internalization (Conference Presentation)

Steen Madsen, Jonathan Gonzalez, Stephanie Molina, Rohit Kumar Nair, Henry Hirschberg

Proceedings Volume 10050, 100500F (2017) https://doi.org/10.1117/12.2253238

KEYWORDS: Tumors, Lanthanum, Medical laser equipment, Cancer, Therapeutic agents, In vitro testing, Toxicity, Tissues, Nanoparticles, Blood

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SPIE Journal Paper | 21 July 2016 Open Access

Focused ultrasound-mediated sonochemical internalization: an alternative to light-based therapies

Jonathan Gonzales, Rohit Nair, Steen J. Madsen, Tatiana Krasieva, Henry Hirschberg

JBO, Vol. 21, Issue 07, 078002, (July 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.7.078002

KEYWORDS: Therapeutics, Tumors, Toxicity, Ultrasonography, Photodynamic therapy, Tissues, Macromolecules, In vitro testing, Luminescence, Oxygen

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Proceedings Article | 9 March 2016 Presentation + Paper

Increasing the efficacy of antitumor glioma vaccines by photodynamic therapy and local injection of allogeneic glioma cells

Catherine Christie, Qian Peng, Steen Madsen, Francisco Uzal, Henry Hirschberg

Proceedings Volume 9690, 96900D (2016) https://doi.org/10.1117/12.2213569

KEYWORDS: Brain, Photodynamic therapy, Cancer, Tumors, Tissues, Medical laser equipment, Radium, OSLO, Standards development

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SPIE Journal Paper | 25 January 2016 Open Access

Photothermal enhancement of chemotherapy mediated by gold-silica nanoshell-loaded macrophages: in vitro squamous cell carcinoma study

Steen Madsen, En-Chung Shih, Qian Peng, Catherine Christie, Tatiana Krasieva, Henry Hirschberg

JBO, Vol. 21, Issue 01, 018004, (January 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.1.018004

KEYWORDS: Near infrared, Tumors, In vitro testing, Nanoparticles, Gold, Toxicity, In vivo imaging, Particles, Absorbance, Cancer

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Proceedings Article | 10 March 2015 Paper

Efficacy of combined photothermal therapy and chemotherapeutic drugs

Steen Madsen, En-Chung Shih, Henry Hirschberg

Proceedings Volume 9305, 93050E (2015) https://doi.org/10.1117/12.2080354

KEYWORDS: Cancer, Near infrared, Tumors, Toxicity, Head, Neck, In vitro testing, Nanoparticles, Breast cancer, Absorption

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Proceedings Article | 10 March 2015 Paper

Macrophage mediated PCI enhanced gene-directed enzyme prodrug therapy

Catherine Christie, Genesis Zamora, Young Kwon, Kristian Berg, Steen Madsen, Henry Hirschberg

Proceedings Volume 9305, 93050C (2015) https://doi.org/10.1117/12.2082590

KEYWORDS: Tumors, Nose, Imaging systems, Linear filtering, Sensors, Digital imaging, Detection and tracking algorithms, Channel projecting optics, Convolution, Matrices

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Proceedings Article | 26 February 2015 Paper

Combined concurrent nanoshell loaded macrophage-mediated photothermal and photodynamic therapies

Henry Hirschberg, Anthony Trinidad, Catherine Christie, Qian Peng, Young Kwon, Steen Madsen

Proceedings Volume 9303, 930322 (2015) https://doi.org/10.1117/12.2082850

KEYWORDS: Photodynamic therapy, Tumors, Gold, Near infrared, Head, Neck, Absorbance, Nanoparticles, Cancer, Medical laser equipment

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SPIE Journal Paper | 23 October 2014 Open Access

Photochemical internalization-mediated nonviral gene transfection: polyamine core-shell nanoparticles as gene carrier

Genesis Zamora, Frederick Wang, Chung-Ho Sun, Anthony Trinidad, Young Jik Kwon, Soo Kyung Cho, Kristian Berg, Steen Madsen, Henry Hirschberg

JBO, Vol. 19, Issue 10, 105009, (October 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.10.105009

KEYWORDS: Tumors, Control systems, Nanoparticles, Photodynamic therapy, Neptunium, Toxicity, Brain, Cancer, In vitro testing, Magnesium

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Proceedings Article | 5 March 2014 Paper

Photochemical internalization (PCI) enhanced nonviral transfection of tumor suppressor and pro-drug activating genes; a potential treatment modality for gliomas

Frederick Wang, Genesis Zamora, Chung-Ho Sun, Anthony Trinidad, Kristian Berg, Steen Madsen, Young Jik Kwon, Henry Hirschberg

Proceedings Volume 8928, 89280B (2014) https://doi.org/10.1117/12.2041627

KEYWORDS: Tumors, Photodynamic therapy, In vitro testing, Cancer, Macromolecules, Green fluorescent protein, Picosecond phenomena, Nanoparticles, OSLO, Brain

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Proceedings Article | 5 March 2014 Paper

Photothermal therapy of human glioma spheroids with gold-silica nanoshells and gold nanorods: a comparative study

Suyog Chhetri, Henry Hirschberg, Steen Madsen

Proceedings Volume 8928, 89280U (2014) https://doi.org/10.1117/12.2038233

KEYWORDS: Nanoparticles, Gold, Absorption, Tissues, Particles, Near infrared, Light scattering, Electrons, Absorbance, Nanorods

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Proceedings Article | 8 March 2013 Paper

Effects of combined photochemical internalization and hyperthermia are sensitively dependent on radiant exposure

Steen Madsen, Christina Schlazer, Aaron Andersen, Stephanie Molina, Henry Hirschberg

Proceedings Volume 8565, 85655F (2013) https://doi.org/10.1117/12.2005407

KEYWORDS: Photodynamic therapy, Macromolecules, Tumors, In vitro testing, Temperature metrology, Therapeutics, Cancer, Toxicity, Oxygen, Oncology

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SPIE Journal Paper | 3 May 2012 Open Access

Photochemical internalization of bleomycin for glioma treatment

Marlon Mathews, En-Chung Shih, Genesis Zamora, Chung-Ho Sun, Henry Hirschberg, Joseph Blickenstaff, Van Vo, Steen Madsen

JBO, Vol. 17, Issue 5, 058001, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.5.058001

KEYWORDS: Tumors, Photodynamic therapy, Brain, Control systems, Toxicity, Blood brain barrier, In vitro testing, Cell death, Two photon excitation microscopy, Plasma

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Proceedings Article | 9 February 2012 Paper

Enhanced gene transfection by photochemical internalization of protomine sulfate/DNA complexes

Henry Hirschberg, Marlon Mathews, En-Chung Shih, Steen Madsen, Young Jik Kwon

Proceedings Volume 8207, 82074S (2012) https://doi.org/10.1117/12.911938

KEYWORDS: Tumors, Cancer, Photodynamic therapy, Stem cells, Green fluorescent protein, Picosecond phenomena, Brain, Macromolecules, Laser therapeutics, Proteins

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Proceedings Article | 18 February 2011 Paper

Photothermal ablation of malignant brain tumors by nanoparticle loaded macrophages

Henry Hirschberg, Seung-Kuk Baek, Young Jik Kwon, Chung-Ho Sun, Steen Madsen

Proceedings Volume 7883, 78833U (2011) https://doi.org/10.1117/12.876224

KEYWORDS: Tumors, Brain, Nanoparticles, Near infrared, Gold, Cancer, Control systems, In vitro testing, Blood brain barrier, Silica

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Proceedings Article | 18 February 2011 Paper

Enhanced transfection of brain tumor suppressor genes by photochemical internalization

Chih Chou, Chung-Ho Sun, Yi-Hong Zhou, Steen Madsen, Henry Hirschberg

Proceedings Volume 7883, 78832D (2011) https://doi.org/10.1117/12.882954

KEYWORDS: Tumors, Green fluorescent protein, Control systems, Photodynamic therapy, Brain, Macromolecules, Proteins, Microscopy, Confocal microscopy, Laser therapeutics

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Proceedings Article | 3 March 2010 Paper

Bypassing the blood-brain barrier: delivery of therapeutic agents by macrophages

Henry Hirschberg, Seung-Kuk Baek, Young Jik Kwon, Chung-Ho Sun, Steen Madsen

Proceedings Volume 7548, 75483Z (2010) https://doi.org/10.1117/12.846958

KEYWORDS: Tumors, Brain, Photodynamic therapy, Blood brain barrier, Collagen, Nanoparticles, Therapeutic agents, Therapeutics, Lanthanum, Blood

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Proceedings Article | 3 March 2010 Paper

Near-infrared-activated gold nanoshells for thermal ablation of macrophages in vitro

Amani Makkouk, Henry Hirschberg, H. Michael Gach, Steen Madsen

Proceedings Volume 7548, 754840 (2010) https://doi.org/10.1117/12.845553

KEYWORDS: Iron, Magnetic resonance imaging, Gold, Tumors, Laser ablation, Visualization, Nanoparticles, Near infrared, In vitro testing, Particles

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Proceedings Article | 13 July 2009 Paper

Targeted opening of the blood brain barrier by ALA-mediated photodynamic therapy

Henry Hirschberg, Qian Peng, Francisco Uzal, David Chighvinadze, Michelle Zhang, Steen Madsen

Proceedings Volume 7380, 73801C (2009) https://doi.org/10.1117/12.822693

KEYWORDS: Blood brain barrier, Brain, Photodynamic therapy, Tumors, Magnetic resonance imaging, Capillaries, Diffusion, Tissues, Pathology, Cancer

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Proceedings Article | 23 February 2009 Paper

Selective disruption of the blood-brain barrier by photochemical internalization

Henry Hirschberg, Michelle Zhang, Michael Gach, Francisco Uzal, David Chighvinadze, Steen Madsen

Proceedings Volume 7161, 716136 (2009) https://doi.org/10.1117/12.810552

KEYWORDS: Blood brain barrier, Chlorine, Tumors, Brain, Photodynamic therapy, Magnetic resonance imaging, Molecules, Macromolecules, Lanthanum, Cancer

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Proceedings Article | 23 February 2009 Paper

Photochemical internalization enhances the efficacy of bleomycin in malignant glioma cells

Steen Madsen, Joseph Blickenstaff, Van Vo, Even Angell-Petersen, Henry Hirschberg

Proceedings Volume 7161, 716132 (2009) https://doi.org/10.1117/12.810097

KEYWORDS: Photodynamic therapy, Brain, Macromolecules, In vitro testing, Blood brain barrier, Toxicity, Tumors, Cancer, Chlorine, Proteins

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Proceedings Article | 26 February 2008 Paper

The effect of motexafin gadolinium on ALA photodynamic therapy in glioma spheroids

Marlon Mathews, Rogelio Sanchez, Chung-Ho Sun, Steen Madsen, Henry Hirschberg

Proceedings Volume 6842, 68422N (2008) https://doi.org/10.1117/12.760260

KEYWORDS: Photodynamic therapy, Tumors, Brain, Gadolinium, Cancer, Tissue optics, In vitro testing, Magnesium, Tissues, In vivo imaging

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Proceedings Article | 8 February 2008 Paper

Evaluation of a novel gadolinium-based contrast agent for intraoperative magnetic resonance imaging

Steen Madsen, Genevieve Wu, Rayland Chow, Sung-Yop Kim, Henry Hirschberg

Proceedings Volume 6842, 68422R (2008) https://doi.org/10.1117/12.760820

KEYWORDS: Tumors, Magnetic resonance imaging, Brain, Gadolinium, Tissues, Surgery, Blood brain barrier, Photodynamic therapy, Image enhancement, Neuroimaging

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Proceedings Article | 8 February 2008 Paper

Disruption of the blood brain barrier following ALA mediated photodynamic therapy

Henry Hirschberg, Qian Peng, Francisco Uzal, David Chighvinadze, Michelle Zhang, Steen Madsen

Proceedings Volume 6842, 68422O (2008) https://doi.org/10.1117/12.767323

KEYWORDS: Blood brain barrier, Photodynamic therapy, Brain, Tumors, Magnetic resonance imaging, Tissues, Neuroimaging, Pathology, Medicine, Tissue optics

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Proceedings Article | 23 March 2007 Paper

Comparing the effects of repetitive and chronic ALA mediated PDT on human glioma spheroids

Marlon Mathews, Chung-Ho Sun, Steen Madsen, Henry Hirschberg

Proceedings Volume 6424, 64242D (2007) https://doi.org/10.1117/12.705430

KEYWORDS: Photodynamic therapy, Tumors, Brain, Tissues, Oxygen, In vitro testing, Medical laser equipment, Luminescence, Molybdenum, Fetus

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Proceedings Article | 23 March 2007 Paper

Photochemical internalization for the treatment of malignant gliomas

Steen Madsen, Khishigzaya Kharkhuu, Kristian Berg, Henry Hirschberg

Proceedings Volume 6424, 64242C (2007) https://doi.org/10.1117/12.705086

KEYWORDS: Macromolecules, Toxicity, Cancer, Photodynamic therapy, Luminescence, Oxygen, In vitro testing, Medicine, Lanthanum, Laser therapeutics

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Proceedings Article | 23 March 2007 Paper

Comparison of ALA and Photofrin in two rat glioma models

Sarah Ziegler, Casey Hall, Cherisse Loucks, Steen Madsen, Stephen Carper

Proceedings Volume 6424, 64242E (2007) https://doi.org/10.1117/12.716527

KEYWORDS: Photodynamic therapy, Cell death, Flow cytometry, Microscopy, Lanthanum, Brain, Tumors, Microelectromechanical systems, Statistical analysis, Luminescence

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Proceedings Article | 23 March 2007 Paper

Increased brain edema following 5-aminolevulinic acid mediated photodynamic in normal and tumor bearing rats

Henry Hirschberg, Even Angell-Petersen, Signe Spetalen, Marlon Mathews, Steen Madsen

Proceedings Volume 6424, 64242B (2007) https://doi.org/10.1117/12.705439

KEYWORDS: Tumors, Brain, Photodynamic therapy, Blood brain barrier, Magnetic resonance imaging, Tissues, Neuroimaging, Distance measurement, Luminescence, Skin

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Introduction: Failure of treatment for high grade gliomas is usually due to local recurrence at the site of surgical resection indicating that a more aggressive form of local therapy, such as PDT, could be of benefit. PDT causes damage to both tumor cells as well as cerebral blood vessels leading to degradation of the blood brain barrier with subsequent increase of brain edema. The increase in brain edema following ALA-PDT was evaluated in terms of animal survival, histopatological changes in normal brain and tumor tissue and MRI scanning. The effect of steroid treatment, to reduce post-treatment PDT induced edema, was also examined. Methods:Tumors were established in the brains of inbred BD-IX and Fisher rats. At various times following tumor induction the animals were injected with ALA ip. and four hours later light treatment at escalating fluences and fluence rates were given. Nontumor bearing control animals were also exposed to ALA-PDT in a similar manner to evaluate damage to normal brain and degree of blood brain barrier (BBB) disruption. Results: Despite a very low level of PpIX production in normal brain, with a 200:1 tumor to normal tissue selectivity ratio measured at a distance of 2 mm from the tumor border, many animals succumbed shortly after treatment. A total radiant energy of 54 J to non-tumor bearing animals resulted in 50% mortality within 5 days of treatment. Treatment of tumor bearing animals with moderate fluence levels produced similar brain edema compared to higher fluence levels. ALA PDT in nontumor bearing animals produced edema that was light dose dependent. PDT appeared to open the BBB for a period of 24-48 hrs after which it was restored. The addition of post operative steroid treatment reduced the incident of post treatment morbidity and mortality. Conclusions: T2 and contrast enhanced T1 MRI scanning proved to be a highly effective and non-evasive modality in following the development of the edema reaction and the degree and time course of BBB dysfunction thus allowing the use of fewer animals.

SPIE Journal Paper | 1 January 2007 Open Access

Determination of fluence rate and temperature distributions in the rat brain; implications for photodynamic therapy

Even Angell-Petersen, Henry Hirschberg, Steen Madsen

JBO, Vol. 12, Issue 01, 014003, (January 2007) https://doi.org/10.1117/12.10.1117/1.2709882

KEYWORDS: Brain, Tumors, Temperature metrology, Diffusion, Monte Carlo methods, Scattering, Absorption, Photodynamic therapy, Light scattering, Optical properties

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Proceedings Article | 22 February 2006 Open Access

Investigating the effects of combined photodynamic and anti-angiogenic therapies using a three-dimensional in vivo brain tumor system

Nzola De Magalhães, Lih-Huei Liaw, Linda Li, Angela Liogys, Steen Madsen, Henry Hirschberg, Bruce Tromberg

Proceedings Volume 6078, 607830 (2006) https://doi.org/10.1117/12.668795

KEYWORDS: Tumors, Photodynamic therapy, Content addressable memory, Therapeutics, Brain, In vivo imaging, Interfaces, Blood vessels, Tissues, 3D modeling

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Proceedings Article | 22 February 2006 Paper

ALA-PDT of glioma cell micro-clusters in BD-IX rat brain

Steen Madsen, Even Angell-Petersen, Signe Spetalen, Stephen Carper, Sarah Ziegler, Henry Hirschberg

Proceedings Volume 6078, 60782Y (2006) https://doi.org/10.1117/12.648969

KEYWORDS: Tumors, Brain, Photodynamic therapy, Blood brain barrier, Luminescence, Toxicity, Control systems, Tissues, Cancer, Lanthanum

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Proceedings Article | 22 February 2006 Paper

Reduction of the invasiveness of human glioma cells by ALA-mediated photodynamic therapy

Henry Hirschberg, Chung-Ho Sun, Steen Madsen

Proceedings Volume 6078, 60782X (2006) https://doi.org/10.1117/12.644940

KEYWORDS: Photodynamic therapy, Tumors, Brain, Collagen, Cancer, In vitro testing, Lanthanum, Ionizing radiation, Proteins, Molybdenum

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Proceedings Article | 25 April 2005 Open Access

Development of a brain tumor model for investigating the effects of photodynamic and anti-angiogenic therapies

Nzola De Magalhaes, Chung-Ho Sun, Steen Madsen, Henry Hirschberg, Bruce Tromberg

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.596910

KEYWORDS: Tumors, Photodynamic therapy, Brain, Therapeutics, Blood vessels, Diagnostics, Quantum wells, Content addressable memory

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Proceedings Article | 25 April 2005 Paper

ALA-mediated photodynamic therapy of experimental malignant glioma in the BD-IX rat model

Henry Hirschberg, Even Angell-Petersen, Qian Peng, Chung-Ho Sun, Dag Sorensen, Steven Carper, Steen Madsen

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.591760

KEYWORDS: Tumors, Photodynamic therapy, Brain, Luminescence, Animal model studies, Tissues, In vitro testing, Tumor growth modeling, Cancer, Cell death

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Proceedings Article | 25 April 2005 Open Access

Addition of ionizing radiation or hyperthermia enhances PDT efficacy in glioma spheroids

Steen Madsen, Chung-Ho Sun, Bruce Tromberg, Josephine Ni, Henry Hirschberg

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.589669

KEYWORDS: Photodynamic therapy, Cell death, Ionizing radiation, Gamma radiation, Control systems, Proteins, Atrial fibrillation, Tumors, Tissues, Luminescence

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Proceedings Article | 13 July 2004 Paper

Interstitial light application for photodynamic therapy in a rat brain tumor model

Even Angell-Petersen, Dag Sorensen, Steen Madsen, Henry Hirschberg

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.527417

KEYWORDS: Brain, Photodynamic therapy, Tumors, Scattering, Animal model studies, Monte Carlo methods, Diffusion, Absorption, Light scattering, Tissue optics

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Proceedings Article | 13 July 2004 Paper

Protoporphyrin IX distribution in rat brain following administration of 5-aminolevulinic acid or its hexylester

Steen Madsen, Scott Friesen, Geir Olav Hjortland, Olav Engebraaten, Qian Peng, Henry Hirschberg

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.527791

KEYWORDS: Tumors, Brain, Luminescence, Animal model studies, Tissues, Biopsy, Blood brain barrier, Data modeling, Cancer, OSLO

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Proceedings Article | 13 July 2004 Paper

Repetitive 5-aminolevulinic acid mediated photodynamic therapy of rat glioma

Henry Hirschberg, Steen Madsen, Even Angell-Petersen, Qian Peng, Mouldy Sioud, Chung-Ho Sun, Dag Sorensen

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.527395

KEYWORDS: Tumors, Photodynamic therapy, Brain, Tissues, Animal model studies, In vitro testing, Luminescence, Tissue optics, In vivo imaging, OSLO

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Proceedings Article | 13 June 2003 Open Access

Development of an in-vivo model for the study of photodynamic therapy and anti-angiogenic treatments

Steen Madsen, Chung-Ho Sun, Bruce Tromberg, Henry Hirschberg

Proceedings Volume 4952, (2003) https://doi.org/10.1117/12.474104

KEYWORDS: Content addressable memory, Photodynamic therapy, In vivo imaging, Tumors, Collagen, Animal model studies, Therapeutics, Cancer, Lanthanum, Medical laser equipment

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Proceedings Article | 27 June 2002 Paper

Temperature- and wavelength-dependent scattering of light during slow heating of porcine septal cartilage

Reshmi Basu, Sergio Diaz-Valdes, Brian Wong, Steen Madsen

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472509

KEYWORDS: Cartilage, Light scattering, Laser scattering, Optical properties, Diffuse reflectance spectroscopy, Laser beam diagnostics, Transmittance, Laser tissue interaction, Scattering, Minerals

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Proceedings Article | 6 June 2002 Open Access

Photodynamic therapy of human glioma spheroids: a comparative study of the effectiveness of 5-aminolevulinic acid and its esters

Steen Madsen, Chung-Ho Sun, Bruce Tromberg, Henry Hirschberg

Proceedings Volume 4612, (2002) https://doi.org/10.1117/12.469345

KEYWORDS: Photodynamic therapy, Tissues, Tumors, Cancer, Lanthanum, Medical laser equipment, OSLO, Molybdenum, In vitro testing, Diffusion

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Proceedings Article | 6 June 2002 Open Access

Effects of low-fluence-rate PDT on glioma spheroids

Steen Madsen, Robin Rodenbush, Chung-Ho Sun, Bruce Tromberg, Henry Hirschberg

Proceedings Volume 4612, (2002) https://doi.org/10.1117/12.469347

KEYWORDS: Photodynamic therapy, Tumors, Tissues, Brain, Carbon dioxide, Cancer, Lanthanum, Medical laser equipment, OSLO, Carbon

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Proceedings Article | 9 July 2001 Open Access

Characterization of optical and thermal distributions from an intracranial balloon applicator for photodynamic therapy

Steen Madsen, Lars Svaasand, Bruce Tromberg, Henry Hirschberg

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434743

KEYWORDS: Photodynamic therapy, Tissue optics, Tissues, Brain, Spherical lenses, Sensors, Thermography, Natural surfaces, Scattering, Optical testing

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Proceedings Article | 9 July 2001 Paper

Wavelength-dependent scattering of light during Nd:YAG laser heating of porcine septal cartilage

Reshmi Basu, Brian Wong, Steen Madsen

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434728

KEYWORDS: Cartilage, Laser beam diagnostics, Laser scattering, Light scattering, Nd:YAG lasers, Laser tissue interaction, Scattering, Collagen, Laser irradiation, Tissue optics

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Proceedings Article | 9 April 2001 Open Access

Fluence rate effects in human glioma spheroids: implications for photodynamic therapy of brain tumors

Steen Madsen, Chung-Ho Sun, Bruce Tromberg, Henry Hirschberg

Proceedings Volume 4248, (2001) https://doi.org/10.1117/12.424447

KEYWORDS: Photodynamic therapy, Tumors, Brain, Tissue optics, Skin, Oxygen, Cancer, Lanthanum, Medical laser equipment, OSLO

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Proceedings Article | 13 June 2000 Paper

Optical property measurements in mammalian cartilage

Steen Madsen, Eugene Chu, Brian Wong

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388057

KEYWORDS: Cartilage, Optical properties, Tissue optics, Scattering, Tissues, Signal attenuation, Optical testing, Monte Carlo methods, Light scattering, Absorption

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Proceedings Article | 6 July 1999 Open Access

Effects of photodynamic therapy on human glioma spheroids

Steen Madsen, Chung-Ho Sun, Eugene Chu, Henry Hirschberg, Bruce Tromberg

Proceedings Volume 3592, (1999) https://doi.org/10.1117/12.351505

KEYWORDS: Photodynamic therapy, Tumors, Brain, Ionizing radiation, Luminescence, Tissues, Tissue optics, Plasma, Lanthanum, Medical laser equipment

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Proceedings Article | 14 June 1999 Open Access

Optical dosimetry in photodynamic therapy of human uterus and brain

Steen Madsen, Lars Svaasand, Henry Hirschberg, Yona Tadir, Bruce Tromberg

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.350032

KEYWORDS: Optical properties, Photodynamic therapy, Tissue optics, Uterus, Brain, Sensors, Optical testing, Modulation, Tissues, Diffusion

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Showing 5 of 49 publications

Proceedings Volume Editor (17)

SPIE Conference Volume | 4 March 2020

Clinical and Translational Neurophotonics 2020

SPIE Conference Volume | 7 June 2019

Clinical and Translational Neurophotonics 2019

SPIE Conference Volume | 11 May 2018

Clinical and Translational Neurophotonics 2018

SPIE Conference Volume | 28 April 2017

Clinical and Translational Neurophotonics

SPIE Conference Volume | 30 June 2016

Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation

Showing 5 of 17 publications

Conference Committee Involvement (26)

Clinical and Translational Neurophotonics 2025

25 January 2025 | San Francisco, California, United States

Clinical and Translational Neurophotonics 2023

28 January 2023 | San Francisco, California, United States

Clinical and Translational Neurophotonics 2022

22 January 2022 | San Francisco, California, United States

Clinical and Translational Neurophotonics 2021

6 March 2021 | Online Only, California, United States

Clinical and Translational Neurophotonics 2020

1 February 2020 | San Francisco, California, United States

Clinical and Translational Neurophotonics 2019

2 February 2019 | San Francisco, California, United States

Clinical and Translational Neurophotonics 2018

27 January 2018 | San Francisco, California, United States

Clinical and Translational Neurophotonics

28 January 2017 | San Francisco, California, United States

Clinical and Translational Neurophotonics

13 February 2016 | San Francisco, California, United States

Novel Biophotonics Techniques and Applications III

24 June 2015 | Munich, Germany