Prof. Thomas Bocklitz Profile

Prof. Thomas Bocklitz

Head of research department at University of Jena

SPIE Involvement:

Conference Chair | Editor | Author

Publications (22)

Proceedings Article | 19 June 2024 Presentation

Sample-size planning tools for multivariate data

Oleg Ryabchykov, Shuxia Guo, Ruihao Luo, Nairveen Ali, Thomas Bocklitz

Proceedings Volume PC13011, PC1301103 (2024) https://doi.org/10.1117/12.3016158

KEYWORDS: Deep learning, Spectroscopy, Photonics, Data modeling, Statistical modeling, Statistical analysis, Imaging spectroscopy, Human-machine interfaces, Cross validation

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Proceedings Article | 19 June 2024 Presentation

Spectral zones based SHAP: enhancing interpretability in spectral deep learning models

Jhonatan Contreras, Thomas Bocklitz

Proceedings Volume PC13011, PC130110A (2024) https://doi.org/10.1117/12.3016969

KEYWORDS: Mathematical modeling, Raman spectroscopy, Deep learning, Spectral models, Reflection, Performance modeling, Machine learning, Artificial intelligence

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Proceedings Article | 19 June 2024 Presentation

No-reference metrics for the characterization of experimental artifacts in fluorescence microscopy

Elena Corbetta, Thomas Bocklitz

Proceedings Volume PC13011, PC1301107 (2024) https://doi.org/10.1117/12.3015933

KEYWORDS: Fluorescence microscopy, Signal to noise ratio, Vignetting, Optical microscopy, Image quality, Image analysis, Visualization, Statistical analysis, Smoothing, Interference (communication)

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Proceedings Article | 19 June 2024 Presentation

Model transfer in Raman spectroscopy: towards a systematic study

Shuxia Guo, Thomas Bocklitz

Proceedings Volume PC13011, PC1301104 (2024) https://doi.org/10.1117/12.3017012

KEYWORDS: Raman spectroscopy, Data modeling, Machine learning, Deep learning, Biological research, Education and training, Molecular spectroscopy, Feature extraction, Diseases and disorders, Chemometrics

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Proceedings Article | 19 June 2024 Presentation

Data science for inverse modelling of photonic measurement processes and FAIR data management of photonic data

Thomas Bocklitz

Proceedings Volume PC13011, PC1301109 (2024) https://doi.org/10.1117/12.3025285

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Proceedings Article | 13 March 2024 Presentation

Enabling virus detection via Raman spectroscopy with magnetic beads as a tool for sample preparation

Susanne Pahlow, Marie Richard-Lacroix, Franziska Hornung, Lea Herrmann, Ziliang Zhao, Stefanie Reuter, Nilay Köse-Vogel, Thomas Mayerhöfer, Julian Hniopek, Oleg Ryabchykov, Thomas Bocklitz, Karina Weber, Ralf Mrowka, Ralf Ehricht, Bettina Löffler, Christian Eggeling, Stefanie Deinhardt-Emmer, Jürgen Popp

Proceedings Volume PC12839, PC128390T (2024) https://doi.org/10.1117/12.3012033

KEYWORDS: Raman spectroscopy, Magnetism, Surface enhanced Raman spectroscopy, Particles, Chemical elements, Spectroscopy, Signal intensity, Proteins, Polymers, Plasmonics

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Proceedings Article | 15 March 2023 Presentation

Transfer learning for Raman spectroscopy in biological applications: A case study for bacterial classification (Conference Presentation)

Milena Królikowska, Thomas Bocklitz

Proceedings Volume PC12392, PC1239213 (2023) https://doi.org/10.1117/12.2651063

KEYWORDS: Raman spectroscopy, Data modeling, Biomedical optics, Visual process modeling, Medical imaging, Statistical modeling, Spectroscopy, Spectral models, Machine vision, Machine learning

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Proceedings Article | 2 March 2022 Paper

Data driven modeling of photonic data

Oleg Ryabchykov, Thomas Bocklitz

Proceedings Volume 11973, 1197302 (2022) https://doi.org/10.1117/12.2609418

KEYWORDS: Data modeling, Image segmentation, Raman spectroscopy, Diagnostics, Tissues, Multimodal imaging, Machine learning, Imaging spectroscopy

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Proceedings Article | 7 December 2021 Paper

Nonlinear spectroscopy for Fabry disease characterization based on cardiomyocytes

E. Tolstik, N. Ali, T. Saeidi, M. Grahovac, S. Guo, P. Arias-Loza, P. Nordbeck, J. Debus, T. Bocklitz, K. Lorenz

Proceedings Volume 11919, 119190R (2021) https://doi.org/10.1117/12.2614591

KEYWORDS: Spectroscopy, Heart, Second-harmonic generation, Proteins, Image segmentation, Image analysis, Signal processing, Tunable lasers, Tissues, Solids

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SPIE Journal Paper | 7 January 2021 Open Access

FLIM data analysis based on Laguerre polynomial decomposition and machine-learning

Shuxia Guo, Anja Silge, Hyeonsoo Bae, Tatiana Tolstik, Tobias Meyer, Georg Matziolis, Michael Schmitt, Jürgen Popp, Thomas Bocklitz

JBO, Vol. 26, Issue 02, 022909, (January 2021) https://doi.org/10.1117/12.10.1117/1.JBO.26.2.022909

KEYWORDS: Fluorescence lifetime imaging, Data modeling, Data analysis, Liver, Luminescence, Chemometrics, Computer simulations, Visualization, Laser phosphor displays, Picosecond phenomena

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Proceedings Article | 19 July 2019 Paper

Raman spectroscopic investigation of plasma by drop coating deposition for clinical application

Jing Huang, Anuradha Ramoji, Michael Kiehntopf, Michel Noutsias, Shuxia Guo, Thomas Bocklitz, Jürgen Popp, Ute Neugebauer

Proceedings Volume 11073, 1107306 (2019) https://doi.org/10.1117/12.2526738

KEYWORDS: Raman spectroscopy, Blood, Principal component analysis, Spectroscopy, Proteins, Chemistry

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Proceedings Article | 15 March 2018 Presentation

Application of spectroscopic methods for the prevention of side effects on patients during chemotherapy (Conference Presentation)

Jürgen Lademann, Maxim Darvin, Johannes Schleusener, Gisela Thiede, Thomas Bocklitz, Martina Meinke, Sora Jung

Proceedings Volume 10493, 104930M (2018) https://doi.org/10.1117/12.2316588

KEYWORDS: Skin, Spectroscopy, Luminescence, Cancer, Oncology, Raman spectroscopy

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SPIE Journal Paper | 14 June 2017 Open Access

Multiplex coherent anti-Stokes Raman scattering microspectroscopy of brain tissue with higher ranking data classification for biomedical imaging

Christoph Pohling, Thomas Bocklitz, Alex Duarte, Cinzia Emmanuello, Mariana Ishikawa, Benjamin Dietzeck, Tiago Buckup, Ortrud Uckermann, Gabriele Schackert, Matthias Kirsch, Michael Schmitt, Jürgen Popp, Marcus Motzkus

JBO, Vol. 22, Issue 06, 066005, (June 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.6.066005

KEYWORDS: Tissues, CARS tomography, Brain, Imaging spectroscopy, Neuroimaging, Biomedical optics, Microscopy, Tumors, Image compression, Brain mapping

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Proceedings Article | 29 April 2017 Paper

Non-linear multimodal imaging for disease diagnostics and treatment monitoring

Thomas Bocklitz, Michael Schmitt, Aleksandar Lukić, Sandro Heuke, Olga Chernavskaia, Tobias Meyer, Jürgen Popp

Proceedings Volume 10340, 103400F (2017) https://doi.org/10.1117/12.2275361

KEYWORDS: Diagnostics, Multimodal imaging, Image analysis, Cancer, Image processing, Image enhancement, Second-harmonic generation, Feature extraction, Tissues, Statistical analysis, Optical parametric oscillators, Visualization

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Proceedings Article | 17 April 2017 Paper

LoC-SERS toward clinical application: quantification of antibiotics in human urine samples

I. Hidi, M. Jahn, K. Weber, M. Pletz, T. Bocklitz, D. Cialla-May, J. Popp

Proceedings Volume 10080, 100800N (2017) https://doi.org/10.1117/12.2250533

KEYWORDS: Surface enhanced Raman spectroscopy, Lab on a chip, Therapeutics, Medicine, Statistical analysis, Raman spectroscopy, Photonics, Silver, Chemistry, Standards development

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Proceedings Article | 3 May 2016 Presentation

Multimodal nonlinear microscopy of biopsy specimen: towards intraoperative diagnostics (Conference Presentation)

Michael Schmitt, Sandro Heuke, Tobias Meyer, Olga Chernavskaia, Thomas Bocklitz, Juergen Popp

Proceedings Volume 9704, 97040H (2016) https://doi.org/10.1117/12.2216043

KEYWORDS: Tissues, In vivo imaging, Microscopy, Diagnostics, Biopsy, Chemical analysis, Tissue optics, Spectroscopy, Molecules, Real time imaging

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Proceedings Article | 27 April 2016 Presentation

Combined fiber probe for fluorescence lifetime and Raman spectroscopy (Conference Presentation)

Sebastian Dochow, Dinglong Ma, Ines Latka, Thomas Bocklitz, Brad Hartl, Julien Bec, Hussain Fatakdawala, Sebastian Wachsmann-Hogiu, Eric Marple, Kirk Urmey, Michael Schmitt, Laura Marcu, Jürgen Popp

Proceedings Volume 9698, 969806 (2016) https://doi.org/10.1117/12.2214151

KEYWORDS: Raman spectroscopy, Luminescence, In vivo imaging, Tissues, Biomedical optics, Raster graphics, Diagnostics, Biological research, Spectroscopy, Fiber optics

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SPIE Journal Paper | 1 April 2013 Open Access

Toward improving fine needle aspiration cytology by applying Raman microspectroscopy

Melanie Becker-Putsche, Thomas Bocklitz, Joachim Clement, Petra Rösch, Jürgen Popp

JBO, Vol. 18, Issue 04, 047001, (April 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.4.047001

KEYWORDS: Raman spectroscopy, Breast cancer, Fine needle aspiration, Tumors, Cancer, Imaging spectroscopy, Breast, Diagnostics, Cell biology, Data modeling

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SPIE Journal Paper | 25 July 2012 Open Access

Classification of inflammatory bowel diseases by means of Raman spectroscopic imaging of epithelium cells

Christiane Bielecki, Claudio Marquardt, Andreas Stallmach, Thomas Bocklitz, Michael Schmitt, Jürgen Popp, Christoph Krafft, Akram Gharbi, Thomas Knosel

JBO, Vol. 17, Issue 7, 076030, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.076030

KEYWORDS: Raman spectroscopy, Tissues, Spectroscopy, Diagnostics, Imaging spectroscopy, Chemometrics, Tissue optics, Blood, Visualization, Proteins

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Proceedings Article | 9 June 2011 Paper

Diagnostics of tumor cells by combination of Raman spectroscopy and microfluidics

U. Neugebauer, S. Dochow, C. Krafft, T. Bocklitz, J. Clement, J. Popp

Proceedings Volume 8087, 80870J (2011) https://doi.org/10.1117/12.890845

KEYWORDS: Raman spectroscopy, Tumors, Microfluidics, Optical tweezers, Capillaries, Cancer, Blood, Spectroscopy, Statistical analysis, Quartz

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Proceedings Article | 9 June 2011 Paper

The multifunctional application of microfluidic lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS) within the field of bioanalytics

Anne März, Bettina Mönch, Angela Walter, Thomas Bocklitz, Wilm Schumacher, Petra Rösch, Michael Kiehntopf, Jürgen Popp

Proceedings Volume 8087, 808707 (2011) https://doi.org/10.1117/12.890086

KEYWORDS: Surface enhanced Raman spectroscopy, Microfluidics, Bacteria, Lab on a chip, Blood, Raman spectroscopy, Mode conditioning cables, Statistical analysis, Biological research, Photonics

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Proceedings Article | 12 February 2010 Paper

Raman spectroscopic characterization of single cells

J. Popp, S, Stöckel, S. Meisel, T. Bocklitz, W. Schumacher, M. Putsche, P. Rösch

Proceedings Volume 7560, 75600B (2010) https://doi.org/10.1117/12.855827

KEYWORDS: Raman spectroscopy, Bacteria, Imaging spectroscopy, Luminescence, Particles, Chemometrics, Algorithm development, Spectroscopy, Micro raman spectroscopy, Breast cancer

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Showing 5 of 22 publications

Proceedings Volume Editor (1)

SPIE Conference Volume | 15 July 2024

Data Science for Photonics and Biophotonics

Conference Committee Involvement (1)

Data Science for Photonics and Biophotonics

10 April 2024 | Strasbourg, France

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