Dr. Thu-Mai Nguyen Profile

Dr. Thu-Mai Nguyen

at Institut Langevin

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Author

Publications (14)

Proceedings Article | 24 April 2017 Presentation

Passive optical coherence elastography using a time-reversal approach (Conference Presentation)

Thu-Mai Nguyen, Ali Zorgani, Mathias Fink, Stefan Catheline, A. Claude Boccara

Proceedings Volume 10067, 1006707 (2017) https://doi.org/10.1117/12.2251839

KEYWORDS: Elastography, Coherence (optics), Tissue optics, Tissues, In vivo imaging, Wave propagation, Ultrafast imaging, Imaging systems, Natural surfaces, Actuators

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SPIE Journal Paper | 21 December 2016 Open Access

Diffuse shear wave imaging: toward passive elastography using low-frame rate spectral-domain optical coherence tomography

Thu-Mai Nguyen, Ali Zorgani, Maxime Lescanne, Claude Boccara, Mathias Fink, Stefan Catheline

JBO, Vol. 21, Issue 12, 126013, (December 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.12.126013

KEYWORDS: Tissues, Elastography, Optical coherence tomography, Wave propagation, Eye, Ultrafast imaging, In vivo imaging, Cornea, Sclera, Actuators

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SPIE Journal Paper | 8 November 2016 Open Access

Moving-source elastic wave reconstruction for high-resolution optical coherence elastography

Bao-Yu Hsieh, Shaozhen Song, Thu-Mai Nguyen, Soon Joon Yoon, Tueng Shen, Ruikang Wang, Matthew O'Donnell

JBO, Vol. 21, Issue 11, 116006, (November 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.11.116006

KEYWORDS: Optical coherence tomography, Wave propagation, Crystals, Speckle, Tissues, Ultrasonography, Sensors, Coherence (optics), Elastography, Imaging systems

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Proceedings Article | 9 March 2016 Presentation + Paper

Elasticity imaging of speckle-free tissue regions with moving acoustic radiation force and phase-sensitive optical coherence tomography

Bao-Yu Hsieh, Shaozhen Song, Thu-Mai Nguyen, Soon Joon Yoon, Tueng Shen, Ruikang Wang, Matthew O’Donnell

Proceedings Volume 9710, 97101F (2016) https://doi.org/10.1117/12.2211522

KEYWORDS: Acoustics, Crystals, Optical coherence tomography, Speckle imaging, Elastography, Speckle, Tissue optics, Crystal optics, Optical tracking, Ophthalmology, Wave propagation, Imaging systems, Ultrasonography

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Phase-sensitive optical coherence tomography (PhS-OCT) can be utilized for quantitative shear-wave elastography using speckle tracking. However, current approaches cannot directly reconstruct elastic properties in speckle-less or speckle-free regions, for example within the crystalline lens in ophthalmology. Investigating the elasticity of the crystalline lens could improve understanding and help manage presbyopia-related pathologies that change biomechanical properties. We propose to reconstruct the elastic properties in speckle-less regions by sequentially launching shear waves with moving acoustic radiation force (mARF), and then detecting the displacement at a specific speckle-generating position, or limited set of positions, with PhS-OCT. A linear ultrasound array (with a center frequency of 5 MHz) interfaced with a programmable imaging system was designed to launch shear waves by mARF. Acoustic sources were electronically translated to launch shear waves at laterally shifted positions, where displacements were detected by speckle tracking images produced by PhS-OCT operating in M-B mode with a 125-kHz A-line rate. Local displacements were calculated and stitched together sequentially based on the distance between the acoustic source and the detection beam. Shear wave speed, and the associated elasticity map, were then reconstructed based on a time-of-flight algorithm. In this study, moving-source shear wave elasticity imaging (SWEI) can highlight a stiff inclusion within an otherwise homogeneous phantom but with a CNR increased by 3.15 dB compared to a similar image reconstructed with moving-detector SWEI. Partial speckle-free phantoms were also investigated to demonstrate that the moving-source sequence could reconstruct the elastic properties of speckle-free regions. Results show that harder inclusions within the speckle-free region can be detected, suggesting that this imaging method may be able to detect the elastic properties of the crystalline lens.

Proceedings Article | 11 March 2015 Paper

Cyclic magnetomotive photoacoustic/ultrasound imaging

Bastien Arnal, Chen-wei Wei, Thu-Mai Nguyen, Junwei Li, Ivan Pelivanov, Xiaohu Gao, Matthew O'Donnell

Proceedings Volume 9323, 93230T (2015) https://doi.org/10.1117/12.2084906

KEYWORDS: Magnetism, In vivo imaging, In vitro testing, Liver, Ultrasonography, Tissues, Nanoparticles, Motion measurement, Photoacoustic imaging, Target detection

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Proceedings Article | 11 March 2015 Paper

Real-time interleaved photoacoustic/ultrasound (PAUS) imaging for interventional procedure guidance

Chen-wei Wei, Thu-Mai Nguyen, Jinjun Xia, Bastien Arnal, Ivan Pelivanov, Matthew O’Donnell

Proceedings Volume 9323, 93233J (2015) https://doi.org/10.1117/12.2084704

KEYWORDS: Tissues, Imaging systems, Mirrors, Ultrasonography, Laser scanners, Signal to noise ratio, Image fusion, Pulsed laser operation, 3D scanning, Visualization

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Proceedings Article | 6 March 2015 Paper

Amplitude-modulated ultrasound radiation force combined with phase-sensitive optical coherence tomography for shear wave elastography

Thu-Mai Nguyen, Shaozhen Song, Bastien Arnal, Emily Wong, Tueng Shen, Ruikang Wang, Matthew O'Donnell

Proceedings Volume 9327, 932705 (2015) https://doi.org/10.1117/12.2084609

KEYWORDS: Ultrasonography, Signal to noise ratio, Tissues, Elastography, Optical coherence tomography, Wave propagation, Transducers, Reconstruction algorithms, Amplitude modulation, Acoustics

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SPIE Journal Paper | 2 January 2015 Open Access

Shear wave elastography using amplitude-modulated acoustic radiation force and phase-sensitive optical coherence tomography

Thu-Mai Nguyen, Bastien Arnal, Shaozhen Song, Zhihong Huang, Ruikang Wang, Matthew O’Donnell

JBO, Vol. 20, Issue 01, 016001, (January 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.1.016001

KEYWORDS: Elastography, Tissues, Optical coherence tomography, Signal to noise ratio, Acoustics, Wave propagation, Transducers, Cornea, Ultrasonography, In vivo imaging

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Proceedings Article | 4 March 2014 Paper

Shear wave elastography using phase sensitive optical coherence tomography

Shaozhen Song, Zhihong Huang, Thu-Mai Nguyen, Emily Wong, Bastien Arnal, Matthew O'Donnell, Ruikang Wang

Proceedings Volume 8934, 89340U (2014) https://doi.org/10.1117/12.2040033

KEYWORDS: Cornea, Optical coherence tomography, Elastography, Tissues, Actuators, Signal to noise ratio, In vivo imaging, Wave propagation, Spatial resolution, Range imaging

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Proceedings Article | 3 March 2014 Paper

Clinically translatable integrated ultrasound and photoacoustic imaging system

Jinjun Xia, Chen-wei Wei, Thu-Mai Nguyen, Bastien Arnal, Ivan Pelivanov, Matthew O'Donnell

Proceedings Volume 8943, 894310 (2014) https://doi.org/10.1117/12.2038025

KEYWORDS: Imaging systems, Ultrasonography, Pulsed laser operation, Mirrors, Laser scattering, System integration, Signal to noise ratio, Field programmable gate arrays, Image fusion, Photoacoustic imaging

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Proceedings Article | 26 February 2014 Paper

Visualization of ultrasonically induced shear wave propagation using phase sensitive optical coherence tomography

Thu-Mai Nguyen, Shaozhen Song, Bastien Arnal, Emily Wong, Ruikang Wang, Matthew O'Donnell

Proceedings Volume 8946, 894607 (2014) https://doi.org/10.1117/12.2038019

KEYWORDS: Tissues, Signal to noise ratio, Optical coherence tomography, Wave propagation, Elastography, Transducers, Visualization, Signal detection, Spatial resolution, Temporal resolution

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SPIE Journal Paper | 17 January 2014 Open Access

Shear wave pulse compression for dynamic elastography using phase-sensitive optical coherence tomography

Thu-Mai Nguyen, Shaozhen Song, Bastien Arnal, Emily Wong, Zhihong Huang, Ruikang Wang, Matthew O'Donnell

JBO, Vol. 19, Issue 01, 016013, (January 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.1.016013

KEYWORDS: Elastography, Tissues, Optical coherence tomography, Wave propagation, Actuators, Signal to noise ratio, Reconstruction algorithms, Electronic filtering, Biomedical optics, Tissue optics

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SPIE Journal Paper | 19 December 2013 Open Access

From supersonic shear wave imaging to full-field optical coherence shear wave elastography

Amir Nahas, Mickael Tanter, Thu-Mai Nguyen, Jean-Marie Chassot, Mathias Fink, A. Claude Boccara

JBO, Vol. 18, Issue 12, 121514, (December 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.12.121514

KEYWORDS: Elastography, Ultrasonography, Wave propagation, Ultrasonics, Optical coherence tomography, Tissues, Coherence (optics), Optical imaging, Cameras, Biomedical optics

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SPIE Journal Paper | 8 November 2013 Open Access

Shear modulus imaging by direct visualization of propagating shear waves with phase-sensitive optical coherence tomography

Shaozhen Song, Zhihong Huang, Thu-Mai Nguyen, Emily Wong, Bastien Arnal, Matthew O'Donnell, Ruikang Wang

JBO, Vol. 18, Issue 12, 121509, (November 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.12.121509

KEYWORDS: Tissues, Wave propagation, Optical coherence tomography, Visualization, Elastography, Tissue optics, Actuators, Reconstruction algorithms, Ultrasonography, Spatial resolution

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