Prof. Uwe Oberheide Profile

Prof. Uwe Oberheide

at TH Köln

SPIE Involvement:

Author

Publications (19)

Proceedings Article | 17 July 2009 Paper

Femtosecond-lentotomy treatment: six-month follow-up of in vivo treated rabbit lenses

S. Schumacher, M. Fromm, U. Oberheide, P. Bock, I. Imbschweiler, H. Hoffmann, A. Beineke, G. Gerten, A. Wegener, H. Lubatschowski

Proceedings Volume 7373, 73730H (2009) https://doi.org/10.1117/12.831899

KEYWORDS: Retina, Optical coherence tomography, Lenses, Tissues, Surgery, Eye, Laser therapeutics, In vivo imaging, Crystals, Laser tissue interaction

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Presbyopia is an age related effect which affects every human at the age of about 40 years. So far reading glasses are the conventional treatment. According to Helmholtz' theory of accommodation one of the mayor reasons for the development of presbyopia is the increasing sclerosis of the lens. In contrast to that the ciliary muscle and the lens capsule remain mostly active and elastic the whole life. So a possible treatment could be the increase of the flexibility of the lens by creating gliding planes with fs-laser pulses inside the lens tissue. In former studies it was shown that fs-laser pulses were able to increase the flexibility of ex vivo porcine lenses as well as ex vivo human donor lenses. Our current aim was to evaluate the effect of the fs-laser pulses on the crystalline lens of living rabbit eyes due to the fs-lentotomy treatment. The main focus of the evaluation was the exclusion of possible side effects of the treatment like cataract formation or retina damage. The treated eyes were monitored using optical coherence tomography (OCT) and Scheimpflug imaging for localizing and studying the tissue effects of the incisions. Furthermore histological sections of the lens and retina were prepared. The rabbits were investigated pre operatively and up to six months post operatively. The fs-laser induced micro incisions were successfully applied to the left lens of each rabbit. The micro incisions within the crystalline lens were detectable with OCT and Scheimpflug imaging up to six month. The imaging within the lens showed a progressive fading of the incisional opacities generated by the femtosecond laser during the six months and no indication of cataract formation was found. OCT and Scheimpflug images emphasize themselves as necessary tools to monitor the micro incisions over time. Histopathological sections of the lens tissue support the findings of the non invasive imaging techniques. Also the histopathological sections of the retina show no thermal induced change due to the irradiation of the fs-pulses.

Proceedings Article | 11 February 2008 Paper

Fs-lentotomy: first in vivo studies on rabbit eyes with a 100 kHz laser system

S. Schumacher, U. Oberheide, M. Fromm, W. Ertmer, G. Gerten, A. Wegener, H. Lubatschowski

Proceedings Volume 6844, 68440V (2008) https://doi.org/10.1117/12.759132

KEYWORDS: Laser cutting, Laser therapeutics, Optical coherence tomography, Laser tissue interaction, Eye, Femtosecond phenomena, Laser vision correction, Laser systems engineering, In vivo imaging, Cornea

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Proceedings Article | 13 July 2007 Paper

fs-Lentotomie: changing the accommodation amplitude of presbyopic human crystalline lenses by fs laser pulses

S. Schumacher, U. Oberheide, H. Theuer, M. Fromm, T. Ripken, G. Gerten, W. Ertmer, H. Lubatschowski

Proceedings Volume 6632, 66321G (2007) https://doi.org/10.1117/12.728197

KEYWORDS: Lenses, Laser therapeutics, Crystals, 3D modeling, Data modeling, Laser cutting, Tissues, Femtosecond phenomena, Finite element methods, Laser crystals

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Proceedings Article | 5 March 2007 Paper

Fs-laser induced flexibility increase in the crystalline lens

S. Schumacher, M. Fromm, R. Lakharia, M. Schaefer, U. Oberheide, T. Ripken, P. Breitenfeld, G. Gerten, W. Ertmer, H. Lubatschowksi

Proceedings Volume 6426, 64261C (2007) https://doi.org/10.1117/12.700148

KEYWORDS: Laser therapeutics, 3D modeling, Crystals, Laser cutting, Tissues, Finite element methods, Data modeling, Optical fibers, Glasses, Laser crystals

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Proceedings Article | 7 March 2006 Paper

FEM simulation of the human lens compared to ex vivo porcine lens cutting pattern: a possible treatment of presbyopia

T. Ripken, P. Breitenfeld, M. Fromm, U. Oberheide, G. Gerten, H. Lubatschowski

Proceedings Volume 6138, 613819 (2006) https://doi.org/10.1117/12.646635

KEYWORDS: Tissues, Finite element methods, Tissue optics, Laser cutting, Eye, Cornea, Optical fibers, Data modeling, Eye models, Natural surfaces

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Proceedings Article | 18 April 2005 Paper

Fs-laser induced elasticity changes to improve presbyopic lens accommodation

Tammo Ripken, Uwe Oberheide, Cerstin Ziltz, Georg Gerten, Holger Lubatschowski

Proceedings Volume 5688, (2005) https://doi.org/10.1117/12.588242

KEYWORDS: Laser cutting, Laser optics, Tissues, Laser tissue interaction, Femtosecond phenomena, Tissue optics, Ultrafast phenomena, Scanners, Glasses, Eye

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Proceedings Article | 13 July 2004 Paper

Investigations for the correction of presbyopia by-fs-laser induced cuts

Tammo Ripken, Uwe Oberheide, Alexander Heisterkamp, Wolfgang Ertmer, Georg Gerten, Holger Lubatschowski

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.528955

KEYWORDS: Laser cutting, Tissues, Laser tissue interaction, Femtosecond phenomena, Eye, Cornea, Tissue optics, Glasses, Light scattering, Scanners

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Proceedings Article | 16 October 2003 Paper

Applications of ultrafast lasers in ophthalmology

Alexander Heisterkamp, Tammo Ripken, Uwe Oberheide, Omid Kermani, Thanongsak Mamom, Wolfgang Drommer, Wolfgang Ertmer, Holger Lubatschowski

Proceedings Volume 5142, (2003) https://doi.org/10.1117/12.500612

KEYWORDS: Eye, Cornea, Surgery, Laser cutting, Tissues, Laser vision correction, Laser therapeutics, Ultrafast lasers, Ophthalmology, Wound healing

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Proceedings Article | 16 October 2003 Paper

First in-vivo studies of presbyopia treatment with ultrashort laser pulses

Tammo Ripken, Alexander Heisterkamp, Uwe Oberheide, Ron Krueger, Elke Luetkefels, Wolfgang Drommer, Wolfgang Ertmer, Holger Lubatschowski

Proceedings Volume 5142, (2003) https://doi.org/10.1117/12.500421

KEYWORDS: Laser cutting, Eye, In vivo imaging, Cornea, Tissue optics, Laser tissue interaction, Femtosecond phenomena, Optical fibers, Laser therapeutics, Tissues

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SPIE Journal Paper | 1 April 2003 Open Access

Optoacoustic imaging for optimization of laser cyclophotocoagulation

Uwe Oberheide, Ingo Bruder, Herbert Welling, Wolfgang Ertmer, Holger Lubatschowski

JBO, Vol. 8, Issue 02, (April 2003) https://doi.org/10.1117/12.10.1117/1.1559998

KEYWORDS: Sensors, Tissues, Tissue optics, Signal detection, Eye, Sclera, Absorption, Laser tissue interaction, Optical properties, Ultrasonography

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Proceedings Article | 13 June 2002 Paper

Therapy monitoring of laser cyclophotocoagulation

Uwe Oberheide, Christoph Lee, Ronald Krebs, Herbert Welling, Wolfgang Ertmer, Holger Lubatschowski

Proceedings Volume 4611, (2002) https://doi.org/10.1117/12.470605

KEYWORDS: Laser therapeutics, Sensors, Absorption, Tissues, Optical properties, Signal processing, Semiconductor lasers, Tissue optics, Scattering, Ultrasonography

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Proceedings Article | 10 June 2002 Paper

Two-dimensional detection of optoacoustic stress transients

Uwe Oberheide, Christoph Lee, Ronald Krebs, Herbert Welling, Wolfgang Ertmer, Holger Lubatschowski

Proceedings Volume 4618, (2002) https://doi.org/10.1117/12.469853

KEYWORDS: Sensors, Metals, Biomedical optics, Tissues, Detector arrays, Ultrasonography, Aluminum, Tomography, Profiling, Tissue optics

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Proceedings Article | 10 June 2002 Paper

Investigation of optical properties of human skin in the UV

Ronald Krebs, Merve Meinhardt, Uwe Oberheide, Holger Lubatschowski, Angelika Anders

Proceedings Volume 4618, (2002) https://doi.org/10.1117/12.469863

KEYWORDS: Skin, Optical properties, Sensors, In vivo imaging, Acoustics, Ultrasonics, Ultraviolet radiation, Tissues, Signal attenuation, Absorption

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Proceedings Article | 24 October 2001 Paper

Optoacoustic imaging for ophthalmology

Uwe Oberheide, Birte Jansen, Ingo Bruder, Holger Lubatschowski, Herbert Welling, Wolfgang Ertmer

Proceedings Volume 4434, (2001) https://doi.org/10.1117/12.446668

KEYWORDS: Absorption, Tissue optics, Eye, Signal detection, Optical properties, Ultrasonography, Biomedical optics, Sensors, Ophthalmology, Semiconductor lasers

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Proceedings Article | 15 June 2001 Paper

Optoacoustic online control for laser cyclophotocoagulation

Uwe Oberheide, Birte Jansen, Ingo Bruder, Holger Lubatschowski, Herbert Welling, Wolfgang Ertmer

Proceedings Volume 4256, (2001) https://doi.org/10.1117/12.429321

KEYWORDS: Semiconductor lasers, Sclera, Signal generators, Sensors, Eye, Photodiodes, Absorption, Optical properties, Tissues, Signal attenuation

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SPIE Journal Paper | 1 April 2001 Open Access

Pulsed photothermal radiometry as a method for investigating blood vessel-like structures

Christoph Schmitz, Uwe Oberheide, Stefan Lohmann, Holger Lubatschowski, Wolfgang Ertmer

JBO, Vol. 6, Issue 02, (April 2001) https://doi.org/10.1117/12.10.1117/1.1344193

KEYWORDS: Absorption, Capillaries, Blood vessels, Radiometry, Blood, Optical properties, Temperature metrology, Tissues, Diffusion, Sensors

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Proceedings Article | 16 November 2000 Paper

Optoacoustical tissue differentiation for on-line therapy control

Uwe Oberheide, Birte Jansen, Ingo Bruder, Holger Lubatschowski, Herbert Welling, Wolfgang Ertmer

Proceedings Volume 4161, (2000) https://doi.org/10.1117/12.409333

KEYWORDS: Sensors, Signal detection, Tissue optics, Reflection, Absorption, Sclera, Laser therapeutics, Tissues, Picosecond phenomena, Semiconductor lasers

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Proceedings Article | 7 June 2000 Paper

Optoacoustic tomography as a diagnostic tool for transscleral laser cyclophotocoagulation

Uwe Oberheide, Arne Buesching, Ingo Bruder, Holger Lubatschowski, Herbert Welling, Wolfgang Ertmer

Proceedings Volume 3908, (2000) https://doi.org/10.1117/12.387511

KEYWORDS: Sclera, Sensors, Tomography, Laser therapeutics, Diagnostics, Semiconductor lasers, Tissue optics, Signal attenuation, Monte Carlo methods, Picosecond phenomena

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Proceedings Article | 14 January 1998 Paper

Pulsed photothermal radiometric investigations of absorbing and scattering media

Christoph Schmitz, Uwe Oberheide, Stefan Lohmann, Holger Lubatschowski, Wolfgang Ertmer

Proceedings Volume 3195, (1998) https://doi.org/10.1117/12.297882

KEYWORDS: Diffusion, Light scattering, Scattering media, Monte Carlo methods, Optical properties, Tissue optics, Detection theory, Scattering, Spectroscopy, Absorption

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Showing 5 of 19 publications

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