Dr. Yuanlong Yang Profile

Dr. Yuanlong Yang

at City College of New York

SPIE Involvement:

Author

Publications (23)

Proceedings Article | 19 March 2013 Paper

The efficacy of Stokes Shift Spectroscopy for detecting prostate and breast cancer tissues

Yang Pu, W. Wang, Yuanlong Yang, Robert Alfano

Proceedings Volume 8577, 857702 (2013) https://doi.org/10.1117/12.2000076

KEYWORDS: Tissues, Collagen, Breast, Spectroscopy, Cancer, Prostate, Breast cancer, Solids, Absorption, Luminescence

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SPIE Journal Paper | 7 January 2013 Open Access

Stokes shift spectroscopic analysis of multifluorophores for human cancer detection in breast and prostate tissues

Yang Pu, Wubao Wang, Yuanlong Yang, Robert Alfano

JBO, Vol. 18, Issue 01, 017005, (January 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.1.017005

KEYWORDS: Tissues, Collagen, Breast, Cancer, Spectroscopy, Prostate, Breast cancer, Solids, Biological research, Luminescence

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SPIE Journal Paper | 10 October 2012 Open Access

Biomarkers spectral subspace for cancer detection

Yi Sun, Yang Pu, Yuanlong Yang, Robert Alfano

JBO, Vol. 17, Issue 10, 107005, (October 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.10.107005

KEYWORDS: Cancer, Tissues, Collagen, Principal component analysis, Luminescence, Signal detection, Breast cancer, Breast, Fluorescence spectroscopy, Biological research

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Proceedings Article | 1 February 2012 Paper

Optical spectroscopic characteristics of lactate and mitochondrion as new biomarkers in cancer diagnosis: understanding Warburg effect

C.-H. Liu, X. H. Ni, Yang Pu, Y. L. Yang, F. Zhou, R. Zuzolo, W. B. Wang, V. Masilamani, A. Rizwan, R. Alfano

Proceedings Volume 8220, 82200Y (2012) https://doi.org/10.1117/12.909249

KEYWORDS: Tissues, Cancer, Breast, Luminescence, Spectroscopy, Optical spectroscopy, Tissue optics, Raman spectroscopy, Acquisition tracking and pointing, Mode conditioning cables

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Proceedings Article | 17 February 2011 Paper

Dynamics of hybrid amoeba proteus containing zoochlorellae studied using fluorescence spectroscopy

C.-H. Liu, B. A. Fong, S. A. Alfano, I. Rakhlin, W. B. Wang, X. H. Ni, Y. L. Yang, F. Zhou, R. C. Zuzolo, R. R. Alfano

Proceedings Volume 7895, 78950Y (2011) https://doi.org/10.1117/12.875293

KEYWORDS: Luminescence, Spectroscopy, Photosynthesis, Fluorescence spectroscopy, Proteins, Cancer, Tumor growth modeling, Chromophores, Organisms, Composites

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The microinjection of organelles, plants, particles or chemical solutions into Amoeba proteus coupled with spectroscopic analysis and observed for a period of time provides a unique new model for cancer treatment and studies. The amoeba is a eukaryote having many similar features of mammalian cells. The amoeba biochemical functions monitored spectroscopically can provide time sequence in vivo information about many metabolic transitions and metabolic exchanges between cellar organelles and substances microinjected into the amoeba. It is possible to microinject algae, plant mitochondria, drugs or carcinogenic solutions followed by recording the native fluorescence spectra of these composites. This model can be used to spectroscopically monitor the pre-metabolic transitions in developing diseased cells such as a cancer. Knowing specific metabolic transitions could offer solutions to inhibit cancer or reverse it as well as many other diseases. In the present study a simple experiment was designed to test the feasibility of this unique new model by injecting algae and chloroplasts into amoeba. The nonradiative dynamics found from these composites are evidence in terms of the emission ratios between the intensities at 337nm and 419nm; and 684nm bands. There were reductions in the metabolic and photosynthetic processes in amoebae that were microinjected with chloroplasts and zoochlorellae as well of those amoebae that ingested the algae and chloroplasts. The changes in the intensity of the emissions of the peaks indicate that the zoochlorellae lived in the amoebae for ten days. Spectral changes in intensity under the UV and 633nm wavelength excitation are from the energy transfer of DNA and RNA, protein-bound chromophores and chlorophylls present in zoochlorellae undergoing photosynthesis. The fluorescence spectroscopic probes established the biochemical interplay between the cell organelles and the algae present in the cell cytoplasm. This hybrid state is indicative that a symbiotic system is in place and the results definitely support the potential use of this unique new model. This model many help in plant / animal and cancer processes.

Proceedings Article | 8 September 2006 Paper

Time-frequency analysis of classical and quantum noise

Y. Yang, L. Cohen

Proceedings Volume 6313, 63130O (2006) https://doi.org/10.1117/12.684024

KEYWORDS: Time-frequency analysis, Signal processing, Oscillators

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Proceedings Article | 13 July 2004 Paper

Stokes shift emission spectroscopy of key biomolecules in human tissues

Robert Alfano, Yuanlong Yang

Proceedings Volume 5326, (2004) https://doi.org/10.1117/12.527961

KEYWORDS: Tissues, Cancer, Luminescence, Molecules, Absorption, Breast, Breast cancer, Spectroscopy, Collagen, Fluorescence spectroscopy

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Proceedings Article | 4 July 2000 Paper

DNA and protein change in human breast tissues by diffuse reflectance spectrum

Yuanlong Yang, Edward Celmer, Jason Koutcher, Peng Ho, Robert Alfano

Proceedings Volume 4082, (2000) https://doi.org/10.1117/12.390525

KEYWORDS: Tissues, Breast, Absorption, Diffuse reflectance spectroscopy, Proteins, Cancer, Luminescence, Scattering, Holmium, Pathology

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Proceedings Article | 19 April 2000 Paper

Ultraviolent and blue 2D fluorescence mapping of gynecological tissues

Alvin Katz, Howard Savage, Yuanlong Yang, Fanan Zeng, Jayson Rome, Steven McCormick, Rubina Cocker, Yizhong Yu, Robert Alfano

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382734

KEYWORDS: Tissues, Luminescence, Tumors, Cancer, Collagen, Ultraviolet radiation, Cervical cancer, Pathology, Image analysis, Shape analysis

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Proceedings Article | 19 April 2000 Paper

DNA and protein change in tissues probed by Kubelka-Munk spectral function

Yuanlong Yang, Edward Celmer, Jason Koutcher, Robert Alfano

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382744

KEYWORDS: Tissues, Absorption, Diffuse reflectance spectroscopy, Breast, Proteins, Scattering, Light scattering, Pathology, Cancer, Spectroscopy

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Proceedings Article | 15 July 1999 Paper

Excitation spectroscopy reveals changes of proteins and the degree of invasion in malignant tissues

Yuanlong Yang, Edward Celmer, Jason Koutcher, Robert Alfano

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356852

KEYWORDS: Tissues, Proteins, Breast, Spectroscopy, Colon, Collagen, Cancer, Pathology, Tumors, Ultrafast laser spectroscopy

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Proceedings Article | 16 April 1998 Paper

Optical fluorescence and Raman biopsy of squamous cell carcinoma from the head and neck

Yuanlong Yang, C. Liu, Howard Savage, Stimson Schantz, Robert Alfano

Proceedings Volume 3250, (1998) https://doi.org/10.1117/12.305364

KEYWORDS: Tissues, Raman spectroscopy, Neck, Head, Luminescence, Lymphatic system, Tumors, Spectroscopy, Biopsy, Diagnostics

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Proceedings Article | 18 August 1997 Paper

Biochemical distinctions between normal and cancerous human breast tissues obtained from fluorescence spectroscopy

Niclolay Zhadin, Yuanlong Yang, Nathan Ockman, Robert Alfano

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280294

KEYWORDS: Luminescence, Tissues, Tumors, Absorption, Breast, Diffuse reflectance spectroscopy, Photons, Ultraviolet radiation, Scattering, Fluorescence spectroscopy

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SPIE Journal Paper | 2 January 1997 Open Access

Fluorescence spectroscopy of dermal wounds in rats

Yuanlong Yang, Lee Mitchell, Robert Alfano

JBO, Vol. 2, Issue 01, (January 1997) https://doi.org/10.1117/12.10.1117/12.259613

KEYWORDS: Skin, Blood, Plasma, Luminescence, Fluorescence spectroscopy, Wound healing, Optical spectroscopy, Tissues, Beam splitters, Photomultipliers

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Proceedings Article | 5 April 1996 Paper

Enhancement of the fluorescence cancer diagnostic method of tissues using diffuse reflectance and the analysis of oxygenation state

Niclolay Zhadin, Yuanlong Yang, Singaravelu Ganesan, Nathan Ockman, Robert Alfano

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237582

KEYWORDS: Tumors, Tissues, Luminescence, Breast, Diffuse reflectance spectroscopy, Diagnostics, Cancer, Oxygen, Absorption, Blood

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Proceedings Article | 5 April 1996 Paper

Optical biopsy fiber-based fluorescence spectroscopy instrumentation

Alvin Katz, Singaravelu Ganesan, Yuanlong Yang, Gui Tang, Yury Budansky, Edward Celmer, Howard Savage, Stimson Schantz, Robert Alfano

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237579

KEYWORDS: Tissues, Breast, Luminescence, Fluorescence spectroscopy, Diagnostics, In vivo imaging, Biopsy, Ultraviolet radiation, Tissue optics, Tumors

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Proceedings Article | 5 April 1996 Paper

Optical spectroscopy of benign and malignant breast tissues

Yuanlong Yang, Alvin Katz, Edward Celmer, Margaret Zurawska-Szczepaniak, Robert Alfano

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237597

KEYWORDS: Tissues, Reflectivity, Luminescence, Breast, Spectroscopy, Diagnostics, Optical spectroscopy, Fluorescence spectroscopy, Pathology, Ultrafast laser spectroscopy

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Proceedings Article | 12 April 1995 Paper

Spectroscopic properties of tryptophan and bacteria

Gui Tang, Yuanlong Yang, Zuo-Zhu Huang, W. Hua, F. Zhou, S. Cosloy, Robert Alfano

Proceedings Volume 2387, (1995) https://doi.org/10.1117/12.206817

KEYWORDS: Luminescence, Bacteria, Information operations, Spectroscopy, Proteins, Molecules, Fluorescence spectroscopy, Ultraviolet radiation, Physics, Biology

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Proceedings Article | 12 April 1995 Paper

Fluorescence spectroscopy to evaluate dermal wounds

Yuanlong Yang, Lee Mitchell, Robert Alfano

Proceedings Volume 2387, (1995) https://doi.org/10.1117/12.206812

KEYWORDS: Skin, Wound healing, Fluorescence spectroscopy, Luminescence, Tissue optics, Chlorine, Ultrafast laser spectroscopy, Biomedical optics, Spectroscopy, Spectrophotometry

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Proceedings Article | 19 May 1994 Paper

Optical spectroscopy methods to detect colon cancer

Yuanlong Yang, Gui Tang, Marc Bessler, Robert Alfano

Proceedings Volume 2135, (1994) https://doi.org/10.1117/12.176008

KEYWORDS: Tissues, Cancer, Luminescence, Colorectal cancer, Colon, Optical spectroscopy, Lamps, Ultrafast laser spectroscopy, Laser optics, In vitro testing

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Proceedings Article | 5 March 1993 Paper

Microspectrophotometry of photosensitizer in single living cell of squamous epithelium carcinoma of human tongue

Yuanlong Yang, Cheng-zhi Jin, Yimin Shen Shen, Paozhong Mao, Yong Xu, Guoyu Zhou

Proceedings Volume 1616, (1993) https://doi.org/10.1117/12.137036

KEYWORDS: Absorption, Tongue, Medicine, Image analysis, Luminescence, Microscopes, Digital image processing, Spectrophotometry, Image processing, Digital imaging

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Proceedings Article | 28 October 1992 Paper

Single laser beam trapping and manipulation of microspheres as a model for biological cells

Zhong Chen, Lei Zhu, Shenyi Wang, Yuanlong Yang

Proceedings Volume 1726, (1992) https://doi.org/10.1117/12.130415

KEYWORDS: Refractive index, Dielectrics, Geometrical optics, Water, Microscopes, Quantum optics, Optical spheres, Optical tweezers, Physics, Optical trapping

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Proceedings Article | 1 June 1992 Paper

Photodynamic therapy in interplay with fluorescence diagnostics in the treatment of human superficial malignancies

Torsten Andersson, Roger Berg, Jonas Johansson, Dick Killander, Katarina Svanberg, Sune Svanberg, Yuanlong Yang

Proceedings Volume 1645, (1992) https://doi.org/10.1117/12.60941

KEYWORDS: Luminescence, Tumors, Photodynamic therapy, Breast cancer, Skin, Tumor growth modeling, Laser induced fluorescence, Diagnostics, Tissues, Dye lasers

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Showing 5 of 23 publications

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