Dr. Zhenyue Chen Profile

Dr. Zhenyue Chen

Senior Scientist at Univ. Zürich

SPIE Involvement:

Author

Area of Expertise:

Optoacoustic imaging , Photoacoustic imaging , Optical imaging , Biomedical imaging , Biophotonics

Websites:

Personal Website | Company Website

Dr. Zhenyue Chen is a Senior Scientist in Prof. Daniel Razansky's group in the Institute of Biomedical Engineering at University and ETH Zurich. He received his Ph. D. degree in Optical Engineering in 2016 from Beijing Institute of Technology. During 2013-2015, he studied as a visiting Ph.D. student in College of Optical Sciences at the University of Arizona, working on fluorescence imaging and polarimetry. During 2016-2019, he worked as a postdoc in Technical University of Munich and Helmholtz Center Munich, focusing on optoacoustic imaging techniques. His current work focuses on biomedical imaging with novel and hybrid modalities including optics, optoacoustics and MRI.

Proceedings Article | 15 March 2023 Presentation

Deep-tissue volumetric microangiography with stereovision diffuse optical localization imaging (sDOLI) in the NIR-II window (Conference Presentation)

Quanyu Zhou, Daniil Nozdriukhin, Zhenyue Chen, Lukas Glandorf, Urs Alexander Tassilo Hofmann, Michael Reiss, Xosé Luís Deán-Ben, Daniel Razansky

Proceedings Volume PC12385, PC123850M (2023) https://doi.org/10.1117/12.2649863

KEYWORDS: Optical imaging, Diffuse optical imaging, Tissues, Visualization, Tissue optics, Light scattering, Blood circulation, 3D image processing, Spatial resolution, Scattering

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Proceedings Article | 9 December 2021 Paper

PVDF spherical matrix array for high resolution cerebral optoacoustic micro-angiography of rodents

Pavel Subochev, Xose Luis Dean-Ben, Zhenyue Chen, Anna Orlova, Daniel Razansky

Proceedings Volume 11923, 119230W (2021) https://doi.org/10.1117/12.2615920

KEYWORDS: Ferroelectric polymers, Spherical lenses, Antennas, Optoacoustics, 3D image processing, Sensors, In vivo imaging, Algorithm development, Signal detection, Reconstruction algorithms

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Proceedings Article | 5 March 2021 Presentation + Paper

Efficient model-based reconstruction framework for acoustic-resolution optoacoustic microscopy

Weiye Li, Urs A. Hofmann, Johannes Rebling, Quanyu Zhou, Zhenyue Chen, Ali Ozbek, Yuxiang Gong, Daniel Razansky, Xose Luis Dean Ben

Proceedings Volume 11642, 1164230 (2021) https://doi.org/10.1117/12.2578971

KEYWORDS: Optoacoustics, Model-based design, Microscopy, Transducers, Spatial resolution, Resolution enhancement technologies, Performance modeling, Acoustics, Visualization, Reconstruction algorithms

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Proceedings Article | 5 March 2021 Presentation + Paper

Optimization of light and sound delivery for in vivo whole-brain optoacoustic angiography of rodents

Pavel Subochev, Ekaterina Sergeeva, Mikhail Kirillin, Daria Kurakina, Anna Orlova, Alexey Kurnikov, Xosé Luís Deán-Ben, Zhenyue Chen, Daniel Razansky

Proceedings Volume 11642, 116422N (2021) https://doi.org/10.1117/12.2579210

KEYWORDS: Optoacoustics, In vivo imaging, Brain, Angiography, Neuroimaging, Signal generators, Imaging systems, Acoustics, Visible radiation, Tissues

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Proceedings Article | 5 March 2021 Presentation + Paper

Polymer-based spherical matrix array for high resolution real-time volumetric optoacoustic micro-angiography

Pavel Subochev, Xosé Luís Deán-Ben, Zhenyue Chen, Anna Orlova, Daniel Razansky

Proceedings Volume 11642, 116421V (2021) https://doi.org/10.1117/12.2579204

KEYWORDS: Spherical lenses, Optoacoustics, Polymers, Visualization, Tomography, Ultrasonography, Ultrafast imaging, Tissues, Time resolved spectroscopy, Spectroscopy

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Proceedings Article | 27 February 2019 Presentation + Paper

Multifocal structured illumination optoacoustic microscopy

Zhenyue Chen, Xosé Luis Deán-Ben, Ali Özbek, Johannes Rebling, Daniel Razansky

Proceedings Volume 10878, 1087816 (2019) https://doi.org/10.1117/12.2508834

KEYWORDS: 3D photoacoustic microscopy, Photoacoustic imaging, Optoacoustics, Microscopy, Acoustics, Detector arrays, Tomography, Ultrasonics, Imaging systems, Spatial resolution

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Proceedings Article | 5 November 2018 Paper

Multifocal structured illumination fluorescence microscopy with large field-of-view and high spatio-temporal resolution

Zhenyue Chen, Ben Mc Larney, Johannes Rebling, Xosé Luis Deán-Ben, Sven Gottschalk, Daniel Razansky

Proceedings Volume 10816, 1081606 (2018) https://doi.org/10.1117/12.2500907

KEYWORDS: Luminescence, Microscopy, Imaging systems, Spatial resolution, Light scattering, Cameras, In vivo imaging, High speed cameras, Microscopes, Diffraction

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Proceedings Article | 19 February 2018 Paper

Hybrid system for in vivo real-time planar fluorescence and volumetric optoacoustic imaging

Zhenyue Chen, Xosé Luís Deán-Ben, Sven Gottschalk, Daniel Razansky

Proceedings Volume 10494, 104946C (2018) https://doi.org/10.1117/12.2287341

KEYWORDS: Imaging systems, Optoacoustics, In vivo imaging, Spatial resolution, Tissue optics, 3D image processing, Tomography, Photoacoustic imaging, Photoacoustic tomography

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Proceedings Article | 16 August 2013 Paper

Influence of range-gated intensifiers on underwater imaging system SNR

Xia Wang, Ling Hu, Qiang Zhi, Zhen-yue Chen, Wei-qi Jin

Proceedings Volume 8912, 89120E (2013) https://doi.org/10.1117/12.2032840

KEYWORDS: Signal to noise ratio, Imaging systems, Modulation transfer functions, Underwater imaging, Scattering, Image intensifiers, Submerged target modeling, Light scattering, Laser scattering, Charge-coupled devices

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Range-gated technology has been a hot research field in recent years due to its high effective back scattering eliminating. As a result, it can enhance the contrast between a target and its background and extent the working distance of the imaging system. The underwater imaging system is required to have the ability to image in low light level conditions, as well as the ability to eliminate the back scattering effect, which means that the receiver has to be high-speed external trigger function, high resolution, high sensitivity, low noise, higher gain dynamic range. When it comes to an intensifier, the noise characteristics directly restrict the observation effect and range of the imaging system. The background noise may decrease the image contrast and sharpness, even covering the signal making it impossible to recognize the target. So it is quite important to investigate the noise characteristics of intensifiers. SNR is an important parameter reflecting the noise features of a system. Through the use of underwater laser range-gated imaging prediction model, and according to the linear SNR system theory, the gated imaging noise performance of the present market adopted super second generation and generation Ⅲ intensifiers were theoretically analyzed. Based on the active laser underwater range-gated imaging model, the effect to the system by gated intensifiers and the relationship between the system SNR and MTF were studied. Through theoretical and simulation analysis to the image intensifier background noise and SNR, the different influence on system SNR by super second generation and generation Ⅲ ICCD was obtained. Range-gated system SNR formula was put forward, and compared the different effect influence on the system by using two kind of ICCDs was compared. According to the matlab simulation, a detailed analysis was carried out theoretically. All the work in this paper lays a theoretical foundation to further eliminating back scattering effect, improving image SNR, designing and manufacturing higher performance underwater range-gated imaging systems.

Proceedings Article | 15 October 2012 Paper

Study of atmospheric effects on infrared polarization imaging system based on polarized Monte Carlo method

Zhenyue Chen, Xia Wang, Mingyang Zhang, Runqiu Xia, Weiqi Jin

Proceedings Volume 8512, 85120H (2012) https://doi.org/10.1117/12.929224

KEYWORDS: Scattering, Polarization, Atmospheric particles, Light scattering, Monte Carlo methods, Photons, Mie scattering, Atmospheric propagation, Atmospheric modeling, Infrared imaging

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