Mr. Wenjie Yu Profile

Wenjie Yu

at China JiLiang Univ

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 20 November 2014 Paper

Experimental demonstration of a Fresnel-reflection based optical fiber biosensor coated with polyelectrolyte multilayers

Wenjie Yu, Tingting Lang

Proceedings Volume 9268, 92681I (2014) https://doi.org/10.1117/12.2070988

KEYWORDS: Optical fibers, Biosensors, Refractive index, Ions, Reflection, Microwave radiation, Sensors, Sodium, Chemical elements, Optical components

Read Abstract +

We report that the end facet of an optical fiber can be coated with polyelectrolyte multilayers (PEM) of polycation (diallyldimethyl ammonium chloride) and polyanion (styrenesulfonate sodium salt) (PDDA+PSS)_n (n is the number of bilayers), which functions effectively as a Fresnel-reflection based biosensor. The experimental setup includes a broadband light source, a 3dB coupler, and an optical spectrum analyzer. Biotin and streptavidin are deposited onto the multilayers-coated end facet sequentially. The light intensity change due to variation of external refractive index is monitored. When the concentrations of streptavidin changes from 0.1mg/ml to 1mg/ml, a linear relationship between the concentration of streptavidin and the reflected optical power at the wavelength of 1530nm is observed. The sensitivity increases from -1.6262×10-³ dB/ppm to -4.7852 ×10^-3 dB/ppm, when the number of PEM increases from 1 to 2. Then we confirm the optimized numbers of bilayers of PEM are 5 through experiment. Selectivity and repeatability of our proposed optical fiber biosensor are verified. When bovine serum albumin (BSA) is added instead of streptavidin, the obtained spectra overlaps with that of biotin’s. The final end facet coated with PEM and biotin-streptavidin can be cleaned using microwave vibration or aqua regia. The microwave vibration method is utilized due to security concern. The optical spectra changes back to the initial one of the optical fiber in air. In conclusion, a Fresnel-reflection based optical fiber biosensor with good sensitivity, selectivity and repeatability is proposed. This biosensor has the advantages of simple structure, low cost and reliability.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years