In vivo human skin dermal–epidermal junction zone delineation by volumetric multiphoton microscopy imaging

Giselle Tian; Zhenguo Wu; Harvey Lui; Jianhua Zhao; Sunil Kalia; Haishan Zeng

doi:10.1117/12.2657147

17 March 2023 In vivo human skin dermal–epidermal junction zone delineation by volumetric multiphoton microscopy imaging

Giselle Tian, Zhenguo Wu, Harvey Lui, Jianhua Zhao, Sunil Kalia, Haishan Zeng

Author Affiliations +

Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520P (2023) https://doi.org/10.1117/12.2657147
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Here we propose a novel method to automatically delineate and quantify DEJ zone morphometrics in human skin on a three dimensional (3D) basis in vivo. Quantitative characterization of the DEJ in terms of 3D interdigitation (I), arithmetic mean roughness (Sa), and root mean square roughness (Sq) were calculated. These DEJ features as a function of age were analyzed. The results show age-dependent morphological differences.

Conference Presentation

Citation Download Citation

Giselle Tian, Zhenguo Wu, Harvey Lui, Jianhua Zhao, Sunil Kalia, and Haishan Zeng "In vivo human skin dermal–epidermal junction zone delineation by volumetric multiphoton microscopy imaging", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520P (17 March 2023); https://doi.org/10.1117/12.2657147

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