Subpixel motion correction for phase-sensitive optical coherence tomography

Huakun Li; Bingyao Tan; Vimal P. Pandiyan; Veluchamy A. Barathi; Ramkumar Sabesan; Leopold Schmetterer; Tong Ling

doi:10.1117/12.2650991

9 March 2023 Subpixel motion correction for phase-sensitive optical coherence tomography

Huakun Li, Bingyao Tan, Vimal P. Pandiyan, Veluchamy A. Barathi, Ramkumar Sabesan, Leopold Schmetterer, Tong Ling

Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC123670U (2023) https://doi.org/10.1117/12.2650991
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Phase-sensitive optical coherence tomography (OCT) enables label-free imaging of structural dynamics with nanoscopic sensitivity. However, the inevitable bulk tissue motions degrade the signal stability and introduce extra phase error. To suppress the motion-induced phase error, we propose a phase-restoring subpixel motion correction method for post-hoc motion correction in Fourier domain OCT, which enables translational shifts of complex-valued OCT images by arbitrary distance. Phantom and in-vivo rodent optoretinogram imaging experiments were conducted to demonstrate the advantages of the proposed method over conventional pixel-level method and the Fourier transform based method.

Conference Presentation

Citation Download Citation

Huakun Li, Bingyao Tan, Vimal P. Pandiyan, Veluchamy A. Barathi, Ramkumar Sabesan, Leopold Schmetterer, and Tong Ling "Subpixel motion correction for phase-sensitive optical coherence tomography", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC123670U (9 March 2023); https://doi.org/10.1117/12.2650991

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