Presentation
15 March 2023 Evaluation of light penetration depth for Imaging Mueller polarimeter operating in a visible wavelength range in reflection geometry: ex-vivo studies of healthy brain white matter (Conference Presentation)
Omar Rodríguez-Núñez, Leonard A. Felger, Romain Gross, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Philippe Schucht, Irena Zubak, Tatiana Novikova
Author Affiliations +
Abstract
The identification of the border between tumor and healthy brain tissue remains a main challenge in glioma surgery. To address this problem we suggest using the Mueller Polarimetric Imaging (MPI) operating in the visible spectral range. In our prior studies, we demonstrated the potential of MPI to assess the anisotropy of healthy brain tissue in fixed and fresh specimens. In this study, we use the MPI system in backscattering geometry in order to evaluate and determine the depth of light penetration through the evaluation of 2D surface polarimetric maps of the formalin-fixed human cerebral corpus callosum sections of different thicknesses.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Omar Rodríguez-Núñez, Leonard A. Felger, Romain Gross, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Philippe Schucht, Irena Zubak, and Tatiana Novikova "Evaluation of light penetration depth for Imaging Mueller polarimeter operating in a visible wavelength range in reflection geometry: ex-vivo studies of healthy brain white matter (Conference Presentation)", Proc. SPIE PC12382, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023, PC1238209 (15 March 2023); https://doi.org/10.1117/12.2650008
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KEYWORDS
Brain

Polarimetry

Neuroimaging

Tumors

Brain mapping

Tissue optics

Anisotropy

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