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16 May 2017 Combined laser-ray tracing and OCT system for biometry of the crystalline lens (Conference Presentation)
Marco Ruggeri, Bianca M. Maceo Heilman, Yue Yao, Yu-Cherng Chang, Alex Gonzalez, Cornelis Rowaan, Ashik Mohamed, Siobhan Williams, Heather A. Durkee, Juan Silgado, Andres Bernal, Esdras Arrieta-Quintero M.D., Arthur Ho, Jean-Marie A. Parel, Fabrice Manns
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Proceedings Volume 10045, Ophthalmic Technologies XXVII; 100451F (2017) https://doi.org/10.1117/12.2256235
Event: SPIE BiOS, 2017, San Francisco, California, United States
Abstract
Age-related changes in the crystalline lens shape and refractive index gradient produce changes in dioptric power and high-order aberrations that influence the optics of the whole eye and contribute to a decrease in overall visual quality. Despite their key role, the changes in lens shape and refractive index gradient with age and accommodation and their effects on high-order aberrations are still not well understood. The goal of this project was to develop a combined laser ray tracing (LRT) and optical coherence tomography (OCT) system to measure high-order aberrations, shape and refractive index gradient in non-human primate and human lenses. A miniature motorized lens stretching system was built to enable imaging and aberrometry of the lens during simulated accommodation. A positioning system was also built to enable on- and off-axis OCT imaging and aberrometry for characterization of the peripheral defocus of the lens. We demonstrated the capability of the LRT-OCT system to produce OCT images and aberration measurements of crystalline lens with age and accommodation in vitro. In future work, the information acquired with the LRT-OCT system will be used to develop an accurate age-dependent lens model to predict the role of the lens in the development of refractive error and aberrations of the whole eye.
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Marco Ruggeri, Bianca M. Maceo Heilman, Yue Yao, Yu-Cherng Chang, Alex Gonzalez, Cornelis Rowaan, Ashik Mohamed, Siobhan Williams, Heather A. Durkee, Juan Silgado, Andres Bernal, Esdras Arrieta-Quintero M.D., Arthur Ho, Jean-Marie A. Parel, and Fabrice Manns "Combined laser-ray tracing and OCT system for biometry of the crystalline lens (Conference Presentation)", Proc. SPIE 10045, Ophthalmic Technologies XXVII, 100451F (16 May 2017); https://doi.org/10.1117/12.2256235
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KEYWORDS
Optical coherence tomography
Crystals
Eye
Imaging systems
Refractive index
Laser crystals
Biophysics
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