Non-interferometric deep optical resolution photoacoustic remote sensing microscopy (Conference Presentation)

Parsin H. HajiReza; Kevan L. Bell; Wei Shi; Roger J. Zemp

doi:10.1117/12.2252972

24 April 2017 Non-interferometric deep optical resolution photoacoustic remote sensing microscopy (Conference Presentation)

Parsin H. HajiReza, Kevan L. Bell, Wei Shi, Roger J. Zemp

Author Affiliations +

Proceedings Volume 10064, Photons Plus Ultrasound: Imaging and Sensing 2017; 1006420 (2017) https://doi.org/10.1117/12.2252972
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

A novel all-optical non-contact photoacoustic microscopy system is introduced. The confocal configuration is used to ensure detection of initial pressure shock wave-induced intensity reflections at the subsurface origin where pressures are largest. Phantom studies confirm signal dependence on optical absorption, index-contrast, and excitation fluence. Taking advantage of a focused1310 nm interrogation beam, the penetration depth of the system is improved to ~ 2mm for an optical resolution system. High signal-to-noise ratios (>60dB) with ~ 2.5 cm working distance from the objective lens to the sample is achieved. Real-time in-vivo imaging of microvasculature and melanoma tumors are demonstrated.

Conference Presentation

Citation Download Citation

Parsin H. HajiReza, Kevan L. Bell, Wei Shi, and Roger J. Zemp "Non-interferometric deep optical resolution photoacoustic remote sensing microscopy (Conference Presentation)", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 1006420 (24 April 2017); https://doi.org/10.1117/12.2252972

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