Laser polarizing system for hyperpolarized xenon (H-Xe) MR imaging of the lungs

Razvan Simionescu

doi:10.1117/12.2283889

29 August 2017 Laser polarizing system for hyperpolarized xenon (H-Xe) MR imaging of the lungs

Razvan Simionescu

Proceedings Volume 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging; 103132L (2017) https://doi.org/10.1117/12.2283889
Event: Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 2002, Ottawa, Ontario, Canada

Abstract

Clinical Magnetic Resonance (MR) imaging relies on the protons of hydrogen atoms (in water molecules) in tissue to provide the signal. Certain organs, for example the lung have been difficult to image because of low signal due to low density and heterogeneity of the tissue that induces susceptibility effects. 129Xe gas (xenon) can help MR imaging of the lungs since the nuclear-spin polarization of the xenon atoms can be increased by laser optical pumping and spin exchange. This process produces hyperpolarized xenon (H-Xe), in which the signal is enhanced by up to a factor of about 104(1).

Citation Download Citation

Razvan Simionescu "Laser polarizing system for hyperpolarized xenon (H-Xe) MR imaging of the lungs", Proc. SPIE 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 103132L (29 August 2017); https://doi.org/10.1117/12.2283889

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