integrated intra-cardiac catheter for polarization sensitive optical coherence tomography-guided radiofrequency ablation (Conference Presentation)

Xiaowei Zhao; Colin Blumenthal; Kilinc U. Orhan; Deniz Dosluoglu; Michael W. Jenkins; Christopher Snyder; Mauricio Arruda; Andrew M. Rollins

doi:10.1117/12.2290560

14 March 2018 integrated intra-cardiac catheter for polarization sensitive optical coherence tomography-guided radiofrequency ablation (Conference Presentation)

Xiaowei Zhao, Colin Blumenthal, Kilinc U. Orhan, Deniz Dosluoglu, Michael W. Jenkins, Christopher Snyder, Mauricio Arruda, Andrew M. Rollins

Author Affiliations +

Proceedings Volume 10471, Diagnostic and Therapeutic Applications of Light in Cardiology 2018; 104710P (2018) https://doi.org/10.1117/12.2290560
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Cardiac arrhythmias are a major source of mortality in the United States. Ablation is the only curative therapy for cardiac arrhythmias, and catheter-based radiofrequency ablation (RFA) through percutaneous access has emerged as the standard care for many arrhythmias. However, current procedures only monitor temperature, impedance and pressure measurements during ablation, which results in incomplete lesion formation (e.g., high recurrence rate for atrial fibrillation patients) and complications. In our previous work, we have shown integration of a commercially available RFA catheter with polarization sensitive optical coherence tomography (PSOCT). This was accomplished by housing the PSOCT probe inside of the RFA catheter with a window at the catheter tip that allows for forward viewing PSOCT imaging. Data from ex vivo experiments have shown that the integrated RFA catheter can be used to confirm catheter tissue apposition and monitor tissue change during ablation by measuring retardance. It was also demonstrated that the PSOCT window does not interfere with normal lesion formation. However, only the catheter tip was integrated, enabling only in vitro experiments. Therefore, we have developed a fully integrated PSOCT RFA catheter based on a commercially available catheter to enable experiments in living swine via percutaneous access. By properly choosing a middle layer sheath to house the PSOCT probe, we reduced the non-uniform rotation distortion (NURD), reduced PSOCT probe tip longitudinal movement due to winding back, improved image quality and stability. Further validation of functionality by simulating RFA procedures in living swine through percutaneous access is ongoing.

Conference Presentation

Citation Download Citation

Xiaowei Zhao, Colin Blumenthal, Kilinc U. Orhan, Deniz Dosluoglu, Michael W. Jenkins, Christopher Snyder, Mauricio Arruda, and Andrew M. Rollins "integrated intra-cardiac catheter for polarization sensitive optical coherence tomography-guided radiofrequency ablation (Conference Presentation)", Proc. SPIE 10471, Diagnostic and Therapeutic Applications of Light in Cardiology 2018, 104710P (14 March 2018); https://doi.org/10.1117/12.2290560

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Radiofrequency ablation

Polarization

Optical coherence tomography

Tissues

Atrial fibrillation

Coherence (optics)

Image quality standards

Show All Keywords

Keywords/Phrases

Search In:

Publication Years