Application of IR thermometry to understanding brain function

Todd Parrish; Michael Iorga

doi:10.1117/12.2297486

26 January 2018 Application of IR thermometry to understanding brain function

Todd Parrish, Michael Iorga

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Proceedings Volume 10540, Quantum Sensing and Nano Electronics and Photonics XV; 1054002 (2018) https://doi.org/10.1117/12.2297486
Event: SPIE OPTO, 2018, San Francisco, California, United States

Abstract

Gliomas are a deadly class of brain tumor for which surgery is currently standard treatment. However, important functional areas must be avoided during tumor removal. Currently intraoperative stimulation-based mapping addresses this, however it has low spatial resolution (~ 1cm) and requires many stimulations. We explore an alternate approach to functional mapping via infrared thermography. Activated brain tissue recruits additional blood supply (neurovascular coupling), which raises local temperature. Intraoperative thermal imaging (ITI) can map several areas simultaneously with relatively high resolution (~0.1 mm). We present our experiences using ITI on two glioma patients, and compare our findings to the stimulation-based gold standard. Initial data suggests good correspondence between these methods, and opens possibilities for a complementary approach. Ultimately, the goal of ITI is to improve patient outcomes by precisely defining the extent of surgical resection and prevent postoperative neurologic deficits.

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Todd Parrish and Michael Iorga "Application of IR thermometry to understanding brain function", Proc. SPIE 10540, Quantum Sensing and Nano Electronics and Photonics XV, 1054002 (26 January 2018); https://doi.org/10.1117/12.2297486

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KEYWORDS

Brain

Tumors

Brain mapping

Surgery

Thermography

Neuroimaging

Magnetic resonance imaging

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