CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 10614 > Article
Paper
16 April 2018 Spectroscopic behavior of pyrrolanthrone and its derivative in aprotic and protic solvents
A. G. Merezhko, M. A. Gerasimova, L. M. Gornostaev, D. A. Tropina, E. A. Slyusareva
Author Affiliations +
Proceedings Volume 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII; 1061423 (2018) https://doi.org/10.1117/12.2303545
Event: XIII International Conference on Atomic and Molecular Pulsed Lasers, 2017, Tomsk, Russia
Abstract
Recently synthesized pyrrolanthrone, naphtho[1,2,3-cd]indole-6(2H)-one (PyAn), and its water-soluble derivative, 3(naphtho[1,2,3-cd]indole-6(2H)-one-2-yl) sodium propylsulfonate, are very promising for anticancer therapy due to both the fluorescent and cytotoxic properties. The present study is focused on the spectroscopic analysis of solvent effects in PyAn and its derivative. An increase of the solvent polarity results in the bathochromic shift in emission and absorption spectra that indicates the involvement of ππ*-type transition. The double linear correlation of Stokes shift with bulk solvent polarity functions (in terms of Lippert’s, Bakhshiev’s and Chamma-Viallet’s models) and microscopic solvent polarity parameter ( ) 30 N ET for aprotic and protic solvents is observed. Both general and specific solvent effects are revealed for the solute-solvent systems. Fluorescence quantum yield, fluorescence lifetime and excited-state dipole moment were defined for PyAn and its derivative in different solvents for the first time. The obtained information is of a great importance for the characterization of intermolecular interactions of drugs with biomolecules for the development of new drug delivery systems.
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
A. G. Merezhko, M. A. Gerasimova, L. M. Gornostaev, D. A. Tropina, and E. A. Slyusareva "Spectroscopic behavior of pyrrolanthrone and its derivative in aprotic and protic solvents", Proc. SPIE 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII, 1061423 (16 April 2018); https://doi.org/10.1117/12.2303545
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 8 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Luminescence
Absorption
Quantum efficiency
Fluorescence spectroscopy
Time resolved spectroscopy
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top