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4 March 2019 Intelligent image-activated cell sorting: principles and applications (Conference Presentation)
Keisuke Goda, Nao Nitta, Takeaki Sugimura, Yoichiroh Hosokawa, Sotaro Uemura, Yasuyuki Ozeki
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Proceedings Volume 10882, Multiphoton Microscopy in the Biomedical Sciences XIX; 108821U (2019) https://doi.org/10.1117/12.2515470
Event: SPIE BiOS, 2019, San Francisco, California, United States
Abstract
I present a newly developed machine intelligence technology called “Intelligent Image-Activated Cell Sorting” [Cell 175, 1 (2018)] that achieves real-time fluorescence-image-based intelligent cell sorting at a high throughput of ~100 events per second. This technology builds on a unique integration of high-throughput cell microscopy, focusing, and sorting techniques on a unique software-hardware platform and hence performs fully automated operation for data acquisition, data processing, decision making, and actuation. Also, I introduce the technology’s broad utility to addressing a fundamental biological question that cannot be answered by conventional technologies – how molecular architectures of cells are connected with their physiological functions.
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Keisuke Goda, Nao Nitta, Takeaki Sugimura, Yoichiroh Hosokawa, Sotaro Uemura, and Yasuyuki Ozeki "Intelligent image-activated cell sorting: principles and applications (Conference Presentation)", Proc. SPIE 10882, Multiphoton Microscopy in the Biomedical Sciences XIX, 108821U (4 March 2019); https://doi.org/10.1117/12.2515470
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KEYWORDS
Data acquisition
Data processing
Microscopy
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