Laser cooling of solids: towards biomedical applications

Quentin Mermillod; Johan Cazals; Alain Glière; Mathieu Dupoy; Nicolas Aubert; Stephan Chabardès

doi:10.1117/12.2507828

1 March 2019 Laser cooling of solids: towards biomedical applications

Quentin Mermillod, Johan Cazals, Alain Glière, Mathieu Dupoy, Nicolas Aubert, Stephan Chabardès

Proceedings Volume 10936, Photonic Heat Engines: Science and Applications; 109360M (2019) https://doi.org/10.1117/12.2507828
Event: SPIE OPTO, 2019, San Francisco, California, United States

Abstract

Focal cooling is a promising alternative therapy for intractable focal epilepsies, avoiding the irreversible neuronal damages induced by resection surgery. However, due to thermal conduction losses, local cooling of a deep brain region remains a challenging objective for thermoelectric or fluidic technologies. Here, we investigated the viability of an optical micro-cooler based on anti-Stokes refrigeration of ytterbium doped YLF crystals, taking into account the medical constraints for implantable device. We realized significant cooling under atmospheric pressure and developed a solution drastically reducing the harmful fluorescence heating of brain-like liquids below 2 K, thus demonstrating the relevance of this technology for biomedical applications.

Citation Download Citation

Quentin Mermillod, Johan Cazals, Alain Glière, Mathieu Dupoy, Nicolas Aubert, and Stephan Chabardès "Laser cooling of solids: towards biomedical applications", Proc. SPIE 10936, Photonic Heat Engines: Science and Applications, 109360M (1 March 2019); https://doi.org/10.1117/12.2507828

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KEYWORDS

Crystals

Luminescence

Absorption

Ytterbium

Biomedical optics

Brain

Solids

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