Spectral and selective laser autofluorescent microscopy of blood films

Yuriy Tomka; Mike Gorsky; Iryna Soltys; Mariya Talakh; Yaroslav Drin; Oxana Yatsko; Olexander Dubolazov; Vasyl Prisyaznyuk; Boris Bodnar; Mykola Shaplavskiy

doi:10.1117/12.2529321

9 September 2019 Spectral and selective laser autofluorescent microscopy of blood films

Yuriy Tomka, Mike Gorsky, Iryna Soltys, Mariya Talakh, Yaroslav Drin, Oxana Yatsko, Olexander Dubolazov, Vasyl Prisyaznyuk, Boris Bodnar, Mykola Shaplavskiy

Author Affiliations +

Proceedings Volume 11105, Novel Optical Systems, Methods, and Applications XXII; 1110515 (2019) https://doi.org/10.1117/12.2529321
Event: SPIE Optical Engineering + Applications, 2019, San Diego, California, United States

Abstract

Experimental studies within the statistical approach of the coordinate structure of the distributions of the intensity of own fluorescence of polycrystalline blood plasma films of patients of the following groups: control group of donors - group 1; patients with non-alcoholic fatty liver disease - group 2; patients with chronic hepatitis - group 3: The average values and ranges of variation of statistical moments of the 1st - 4th orders determined within the representative samples, which characterize the coordinate distributions of the intensity values of autofluorescent microscopic images of samples of polycrystalline blood plasma films within groups 1, 2, 3. The analysis of the operating characteristics of the power of the method of laser polarization mapping of two-dimensional distributions of the intensity values of its own fluorescence of microscopic images based on the determination of the sensitivity values, specificity and accuracy of the diagnostic test.

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Yuriy Tomka, Mike Gorsky, Iryna Soltys, Mariya Talakh, Yaroslav Drin, Oxana Yatsko, Olexander Dubolazov, Vasyl Prisyaznyuk, Boris Bodnar, and Mykola Shaplavskiy "Spectral and selective laser autofluorescent microscopy of blood films", Proc. SPIE 11105, Novel Optical Systems, Methods, and Applications XXII, 1110515 (9 September 2019); https://doi.org/10.1117/12.2529321

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