Multispectral tissue analysis with fiber probes in 0,3-16µm range for tumor margin guidance (Conference Presentation)

Viacheslav G. Artyushenko

doi:10.1117/12.2544399

25 March 2020 Multispectral tissue analysis with fiber probes in 0,3-16µm range for tumor margin guidance (Conference Presentation)

Viacheslav G. Artyushenko

Author Affiliations +

Proceedings Volume 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry; 1123605 (2020) https://doi.org/10.1117/12.2544399
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Review of key spectroscopy methods for label free tissue analysis - compared for tumour margin guidance capability. Comparison of key methods: Raman scattering, Mid IR-absorption, Diffuse NIR-reflection and fluorescence, – enables to select the most sensitive, specific and accurate methods for kidney cancer analysis in-vitro: fluorescence and combi Fluo/ Mid IR-absorption. 2 other combi-methods were tested ex-vivo for: a) Oral cancer – HW-Raman + Fluorescence; b) Colorectal Cancer – Fluorescence + Near-Infrared Spectroscopy. Chemometric treatment of spectral data obtained with combi-fiber probes enables to improve discrimination capability vs the single methods and shows the capability to use multi-spectral fiber spectroscopy in clinical oncology.

Conference Presentation

Citation Download Citation

Viacheslav G. Artyushenko "Multispectral tissue analysis with fiber probes in 0,3-16µm range for tumor margin guidance (Conference Presentation)", Proc. SPIE 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, 1123605 (25 March 2020); https://doi.org/10.1117/12.2544399

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