Holistic quantification of cutaneous microcirculation with spatial frequency domain imaging (SFDI) and coherent hemodynamics spectroscopy (CHS) based on a dynamic microcirculation PIPE model (Conference Presentation)

Min Xu; Yang Zheng; Xinlin Chen; Weihao Lin; Bixin Zeng

doi:10.1117/12.2547547

9 March 2020 Holistic quantification of cutaneous microcirculation with spatial frequency domain imaging (SFDI) and coherent hemodynamics spectroscopy (CHS) based on a dynamic microcirculation PIPE model (Conference Presentation)

Min Xu, Yang Zheng, Xinlin Chen, Weihao Lin, Bixin Zeng

Author Affiliations +

Proceedings Volume 11239, Dynamics and Fluctuations in Biomedical Photonics XVII; 112390K (2020) https://doi.org/10.1117/12.2547547
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We report holistic quantification of cutaneous microcirculation with spatial frequency domain imaging (SFDI) and coherent hemodynamics spectroscopy (CHS) based on a dynamic microcirculation PIPE model. A simple device was developed to induce periodic variations in cutaneous blood volume and flow velocity. Both baseline and dynamic features of cutaneous microcirculation for healthy subjects were completely quantified. The CHS findings were further related to SSMD-SFDI imaging of the same healthy subjects under reactive hyperemia protocol. The results demonstrate spatial frequency domain imaging and coherent hemodynamics spectroscopy based on the dynamic microcirculation PIPE model provides a valuable tool for functional studies with hemodynamic-based techniques.

Conference Presentation

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Min Xu, Yang Zheng, Xinlin Chen, Weihao Lin, and Bixin Zeng "Holistic quantification of cutaneous microcirculation with spatial frequency domain imaging (SFDI) and coherent hemodynamics spectroscopy (CHS) based on a dynamic microcirculation PIPE model (Conference Presentation)", Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 112390K (9 March 2020); https://doi.org/10.1117/12.2547547

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KEYWORDS

Coherence imaging

Hemodynamics

Blood

Spectroscopy

Imaging spectroscopy

Capillaries

Oxygen

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