Quantification of ex-vivo tissue activity by polarization dynamics imaging using Jones matrix optical coherence tomography

Pradipta Mukherjee; Arata Miyazawa; Larina Shen; Shinichi Fukuda; Toshiharu Yamashita; Yuki Oka; Ibrahim Abd El-Sadek; Shuichi Makita; Satoshi Matsusaka; Tetsuro Oshika; Hideaki Kano; Yoshiaki Yasuno

doi:10.1117/12.2573237

15 June 2020 Quantification of ex-vivo tissue activity by polarization dynamics imaging using Jones matrix optical coherence tomography

Pradipta Mukherjee, Arata Miyazawa, Larina Shen, Shinichi Fukuda, Toshiharu Yamashita, Yuki Oka, Ibrahim Abd El-Sadek, Shuichi Makita, Satoshi Matsusaka, Tetsuro Oshika, Hideaki Kano, Yoshiaki Yasuno

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Proceedings Volume 11521, Biomedical Imaging and Sensing Conference 2020; 115210R (2020) https://doi.org/10.1117/12.2573237
Event: SPIE Technologies and Applications of Structured Light, 2020, Yokohama, Japan

Abstract

A new method for quantitative assessment of tissue dynamics and activity is presented. The method is based on polarizationsensitive optical coherence tomography. Temporal variance of birefringence and temporal polarization uniformity are used to assess the tissue dynamics. These methods are applied to hourly time-course evaluation of tissue activity of ex-vivo dissected mouse heart.

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Pradipta Mukherjee, Arata Miyazawa, Larina Shen, Shinichi Fukuda, Toshiharu Yamashita, Yuki Oka, Ibrahim Abd El-Sadek, Shuichi Makita, Satoshi Matsusaka, Tetsuro Oshika, Hideaki Kano, and Yoshiaki Yasuno "Quantification of ex-vivo tissue activity by polarization dynamics imaging using Jones matrix optical coherence tomography", Proc. SPIE 11521, Biomedical Imaging and Sensing Conference 2020, 115210R (15 June 2020); https://doi.org/10.1117/12.2573237

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