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Optical quality in microscopy has reached a point where it is only limited by aberrations arising from sample inhomogeneities or refractive index mismatch in the focusing path. In this scenario adaptive optics is playing an increasingly important role. Most common microscopy AO setups rely on sensor-less algorithms and are designed to optimize only for one field. We present a method capable of measuring aberrations in every point on the field-of-view. This combined with the use of two deformable lenses permits to correct for field dependent aberrations in a closed loop MCAO system with virtually no changes in the microscopy setup.
Tommaso Furieri andStefano Bonora
"Multi conjugated adaptive optics with closed loop and no wavefront sensor in microscopy using deformable lenses", Proc. SPIE 11652, Adaptive Optics and Wavefront Control for Biological Systems VII, 116520E (5 March 2021); https://doi.org/10.1117/12.2578139
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Tommaso Furieri, Stefano Bonora, "Multi conjugated adaptive optics with closed loop and no wavefront sensor in microscopy using deformable lenses," Proc. SPIE 11652, Adaptive Optics and Wavefront Control for Biological Systems VII, 116520E (5 March 2021); https://doi.org/10.1117/12.2578139