Coherent Raman imaging with enhanced sensitivity by a frequency-modulated portable light source

Maximilian Brinkmann; Tim Hellwig; Thomas Würthwein; Carsten Fallnich

doi:10.1117/12.2578094

5 March 2021 Coherent Raman imaging with enhanced sensitivity by a frequency-modulated portable light source

Maximilian Brinkmann, Tim Hellwig, Thomas Würthwein, Carsten Fallnich

Proceedings Volume 11655, Label-free Biomedical Imaging and Sensing (LBIS) 2021; 1165515 (2021) https://doi.org/10.1117/12.2578094
Event: SPIE BiOS, 2021, Online Only

Abstract

We present multicolor coherent Raman imaging (CRI) with two orders of magnitude enhanced sensitivity accomplished by a frequency modulation (FM) at 20 MHz of a portable fiber optical parametric oscillator (FOPO). The FM is combined with a rapid and wide tunability for accessing Raman bands between 700 and 3500 1/cm within only 5 ms. This development constitutes an important step for advancing CRI microscopy in terms of portability and sensitivity for applications in medical diagnostics or environmental sensing.

Conference Presentation

Citation Download Citation

Maximilian Brinkmann, Tim Hellwig, Thomas Würthwein, and Carsten Fallnich "Coherent Raman imaging with enhanced sensitivity by a frequency-modulated portable light source", Proc. SPIE 11655, Label-free Biomedical Imaging and Sensing (LBIS) 2021, 1165515 (5 March 2021); https://doi.org/10.1117/12.2578094

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