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1 August 2021 Patterned organic LEDs for interfacing neurons
Caroline Murawski, Yali Deng, Andrew Morton, Changmin Keum, Stefan R. Pulver, Malte C. Gather
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Proceedings Volume 11808, Organic and Hybrid Light Emitting Materials and Devices XXV; 118080D (2021) https://doi.org/10.1117/12.2595125
Event: SPIE Organic Photonics + Electronics, 2021, San Diego, California, United States
Abstract
Organic light-emitting diodes (OLEDs) offer unique properties such as large-area emission, compatibility with flexible substrates, tuning of emitted spectrum, and structuring into high-density arrays. This makes OLEDs attractive for biomedical applications like on-chip sensing or wearable health monitoring and, more recently, also to control the activity of neurons through a method called optogenetics. So far, most light sources used in optogenetics provide limited spatial resolution. In this contribution, we present micropatterned OLEDs that are capable of precisely controlling neuronal activity in Drosophila melanogaster (fruit fly) larvae. The OLEDs provide highly confined light stimuli to individual abdominal segments, which allows precise activation and inhibition of sensory input in larvae. Our work demonstrates the advantages of OLED technology for neuroscience and provides prospects for future integration of OLEDs in implants.
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Caroline Murawski, Yali Deng, Andrew Morton, Changmin Keum, Stefan R. Pulver, and Malte C. Gather "Patterned organic LEDs for interfacing neurons", Proc. SPIE 11808, Organic and Hybrid Light Emitting Materials and Devices XXV, 118080D (1 August 2021); https://doi.org/10.1117/12.2595125
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KEYWORDS
Organic light emitting diodes
Neurons
Light emitting diodes
Optogenetics
Biomedical optics
Light sources
Neuroscience
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