Laboratory-based phase and absorption tomography for micro-imaging of annual layers in human tooth cementum, paraffin-embedded nerve and zebrafish embryo

Alexandra Migga; Georg Schulz; Griffin Rodgers; Melissa Osterwalder; Christine Tanner; Holger Blank; Iwan Jerjen; Phil Salmon; William Twengström; Mario Scheel; Timm Weitkamp; Christian M. Schlepütz; Jan S. Bolten; Jörg Huwyler; Gerhard Hotz; Srinivas Madduri; Bert Müller

doi:10.1117/12.2597926

7 October 2021 Laboratory-based phase and absorption tomography for micro-imaging of annual layers in human tooth cementum, paraffin-embedded nerve and zebrafish embryo

Alexandra Migga, Georg Schulz, Griffin Rodgers, Melissa Osterwalder, Christine Tanner, Holger Blank, Iwan Jerjen, Phil Salmon, William Twengström, Mario Scheel, Timm Weitkamp, Christian M. Schlepütz, Jan S. Bolten, Jörg Huwyler, Gerhard Hotz, Srinivas Madduri, Bert Müller

Author Affiliations +

Proceedings Volume 11840, Developments in X-Ray Tomography XIII; 118400T (2021) https://doi.org/10.1117/12.2597926
Event: SPIE Optical Engineering + Applications, 2021, San Diego, California, United States

Abstract

Inline phase tomography using synchrotron radiation with sub-micrometer voxel sizes is nowadays the gold standard for investigation of soft and hard tissues with micron resolution. Recent developments on detectors and X-ray sources allow the transfer of the technique into laboratory environment. For the comparison of three manufacturers, we performed microtomography with advanced laboratory microtomography devices with micron resolution on a porcine nerve, a zebrafish embryo and a historic human tooth. These data sets were also compared with data acquired at the ANATOMIX beamline at Synchrotron Soleil and the TOMCAT beamline at SLS. For the lab-based experiments following scanners were chosen: Skyscan 2214 (Bruker-microCT, Kontich, Belgium), Xradia 620 Versa (Zeiss, Oberkochen, Germany) and a prototype with a MetalJet X-ray source from Exillum from the company Exciscope (Stockholm, Sweden). All devices contained detectors including X-ray optics.

Conference Presentation

Citation Download Citation

Alexandra Migga, Georg Schulz, Griffin Rodgers, Melissa Osterwalder, Christine Tanner, Holger Blank, Iwan Jerjen, Phil Salmon, William Twengström, Mario Scheel, Timm Weitkamp, Christian M. Schlepütz, Jan S. Bolten, Jörg Huwyler, Gerhard Hotz, Srinivas Madduri, and Bert Müller "Laboratory-based phase and absorption tomography for micro-imaging of annual layers in human tooth cementum, paraffin-embedded nerve and zebrafish embryo", Proc. SPIE 11840, Developments in X-Ray Tomography XIII, 118400T (7 October 2021); https://doi.org/10.1117/12.2597926

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available