Optical properties of adult zebrafish brain detected by optical coherence tomography and photoacoustic imaging in vivo

Yintao Lan; Weijian Gao; Mengyu Zhou; Jing Huang; Shuqi Gan; Yao Xu; Ting Lu; Yiqing Zhang; Jian Zhang

doi:10.1117/12.2603247

31 August 2021 Optical properties of adult zebrafish brain detected by optical coherence tomography and photoacoustic imaging in vivo

Yintao Lan, Weijian Gao, Mengyu Zhou, Jing Huang, Shuqi Gan, Yao Xu, Ting Lu, Yiqing Zhang, Jian Zhang

Author Affiliations +

Proceedings Volume 11907, Sixteenth National Conference on Laser Technology and Optoelectronics; 1190733 (2021) https://doi.org/10.1117/12.2603247
Event: Sixteenth National Conference on Laser Technology and Optoelectronics, 2021, Shanghai, China

Abstract

The whole brain imaging of animal models is a major challenge in the current optical field, especially in freely moving animals. In this paper, in vivo high-resolution and long-term characterization of zebrafish brain were achieved with optical coherence tomography (OCT) and photoacoustic microscopy (PAM). The combination of OCT and PAM demonstrated gratifying results in vivo characterization of adult zebrafish brain’s complex structure.

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Yintao Lan, Weijian Gao, Mengyu Zhou, Jing Huang, Shuqi Gan, Yao Xu, Ting Lu, Yiqing Zhang, and Jian Zhang "Optical properties of adult zebrafish brain detected by optical coherence tomography and photoacoustic imaging in vivo", Proc. SPIE 11907, Sixteenth National Conference on Laser Technology and Optoelectronics, 1190733 (31 August 2021); https://doi.org/10.1117/12.2603247

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