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Characterisation of the elasticity of biological cells is growing as a way to study cell biology. Cell mechanics are related to cell behaviour and potential applications offer great opportunities. Current methods to study cell mechanics are often limited as they may require contact or greater resolution. From the state of the art, the use of high frequency ultrasound (phonons) is one of the most promising since it offers label-free, high resolution and can be integrated on optical microscopes.
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Fernando Perez-Cota, Rafael Fuentes-Dominguez, Salvatore La Cavera III, William Hardiman, Mengting Yao, Richard J. Smith, Matt Clark, "Picosecond ultrasonics for cell imaging and characterisation," Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119600G (3 March 2022); https://doi.org/10.1117/12.2609638